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Geospatial technologies help track real-time movements of sex offenders

Convicted sex offenders continue to move freely within communities, including in restricted areas, despite laws designed to limit their movements. A new study, by Alan Murray from Arizona State University and colleagues, uses new tracking techniques to better understand the actual movements of sex offenders. This information can help develop effective strategies to promote public safety.

30 Jan 2013

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

AvidBiologics Inc., a life sciences company developing antibody-drug conjugates (ADCs), announces the conclusion of an agreement with the National Research Council Canada (NRC) to develop three novel ADCs for the treatment of cancer.

30 Jan 2013

HIV-positive patients have higher incidence of non-melanoma skin cancers

HIV-positive patients have a higher incidence of non-melanoma skin cancers, according to a Kaiser Permanente study that appears in the current online issue of the Journal of the National Cancer Institute. Specifically, basal cell and squamous cell carcinomas occur more than twice as often among HIV-positive individuals compared to those who are HIV-negative.

30 Jan 2013

FBH1 gene helps turn up the effect of chemotherapy

Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research and Innovation Centre (BRIC) and Center for Healthy Aging, University of Copenhagen, now show that the gene FBH1 helps turn up the effect of chemotherapy.

30 Jan 2013

Low-income and minority parents/guardians receptive toward vaccinating boys against HPV

A new Boston University School of Medicine (BUSM) study has found that low-income and minority parents/guardians were receptive toward vaccinating boys against Human Papilloma Virus (HPV). However, racial/ethnic differences emerged in attitudes regarding school-entry mandates. The findings appear online in the journal Clinical Pediatrics.

30 Jan 2013

DFG again approves funding for Mainz University to promote cardiovascular research

The German Research Foundation (DFG) has again approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote cardiovascular research - for the second time within only a few weeks.

30 Jan 2013

FDA approves Genzyme’s KYNAMRO to treat homozygous familial hypercholesterolemia

Genzyme, a Sanofi company, and Isis Pharmaceuticals Inc., today announced that the U.S. Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for KYNAMROTM (mipomersen sodium) injection.

30 Jan 2013

SOD1 enzyme protects cells by regulating cell energy and metabolism

Just like a comic book super hero, you could say that the enzyme superoxide dismutase (SOD1) has a secret identity. Since its discovery in 1969, scientists believed SOD1's only role was to protect living cells against damage from free radicals. Now, researchers at the Johns Hopkins Bloomberg School of Public Health have discovered that SOD1 protects cells by regulating cell energy and metabolism. The results of their research were published January 17, 2013, in the journal Cell.

30 Jan 2013

Glenmark third quarter consolidated revenue increases 33.96% to Rs. 13812.59M

Glenmark Pharmaceuticals Limited (GPL), the research-led global integrated pharmaceutical company announced its results for the third quarter ended December 31, 2012.

30 Jan 2013

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its investigational protein therapeutic, ACE-536, to treat anemia in patients with myelodysplastic syndromes (MDS).

30 Jan 2013

Phenformin decreases size of lung tumors and increases survival in mice

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer.

30 Jan 2013

Enterprise Ireland welcomes Irish Minister to its pavilion at Arab Health 2013

Enterprise Ireland Dubai, the regional arm of the Irish government organisation responsible for the development and growth of Irish enterprises in world markets, welcomed Minister Costello TD, Irish Minister of State for Trade and Development to its pavilion at this year's Arab Health exhibition.

30 Jan 2013

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

Non-coding RNA essential for normal embryonic cardiogenesis

Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. Scientists from the Max Planck Institute for Molecular Genetics in Berlin, in collaboration with colleagues at MIT and the Broad Institute in Boston, have now been able to demonstrate that RNA molecules, which do not act as templates for protein synthesis, participate in these processes as well.

30 Jan 2013

Cambodian health officials strengthen avian flu awareness campaigns after 2 more deaths

"Two more children have died in Cambodia of bird flu, bringing the number of fatal cases this year to four and the number of cases overall to five," the Associated Press/Wall Street Journal reports, noting only three cases were reported in all of 2012. "WHO says bird flu, also known as avian influenza, or H5N1, has killed 360 other people worldwide since surfacing in 2003," with most cases "linked to contact with infected poultry," the news agency writes.

30 Jan 2013

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

OncoPep, Inc. today announced that the Company has initiated a Phase 1/2a clinical trial evaluating PVX-410, a multi-peptide therapeutic cancer vaccine, in patients with smoldering multiple myeloma, an asymptomatic precursor of multiple myeloma, which is an incurable cancer of the plasma cells.

30 Jan 2013

U-M to host 11th-annual Depression on College Campuses Conference on Feb. 26-27

Rather than seeking out healthy treatment options, many college students experiencing symptoms of depression or anxiety too often resort to unhealthy coping practices like drug use, drinking, or self-injury.

30 Jan 2013

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

ImmunoCellular Therapeutics, Ltd. announced that the US Food and Drug Administration (FDA) has allowed the investigational new drug (IND) application for ICT-140, paving the way for conducting a clinical trial.

30 Jan 2013

Human Brain Project to link basic research with disease treatment

King's College London is part of an international consortium of scientists who have today been awarded a grant of over one billion euros, over ten years, to simulate 'everything we know about the human brain' in supercomputers.

30 Jan 2013

UNFPA executive director speaks about necessity of family planning services at A.U. maternal health event

"Ensuring availability of family planning services and their acceptability to every woman, man and to young people, would improve the health of mothers and children in Africa, besides saving health care systems unnecessary expenditure, according to Dr. Babatunde Osotimehin, executive director of the U.N. Population Fund (UNFPA)," who spoke at a maternal health event on the sidelines of the African Union summit in Addis Ababa, Ethiopia, on Monday, PANA/AfriqueJet reports.

30 Jan 2013