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Medications often prescribed for PAH could affect heart health of treated patients

A research team with the Faculty of Medicine & Dentistry at the University of Alberta reported findings that significantly improve understanding of how widely used drugs in Pulmonary Arterial Hypertension (PAH) affect the heart health of treated patients.

18 Jan 2013

Blog features two posts on new NTD publications

The Global Network for Neglected Tropical Diseases' (NTDs) "End the Neglect" blog features two posts discussing the first anniversary of the London Declaration and two recently released reports on progress against NTDs.

18 Jan 2013

$ADT increases risk of fracture incidence after treatment completion in men with prostate cancer$

ADT increases risk of fracture incidence after treatment completion in men with prostate cancer

In what is believed to be the first study to describe the impact on men with a 'high' risk of bone fracture who are receiving long-term androgen deprivation therapy (ADT) for prostate cancer, new research from The Cancer Institute of New Jersey shows this population to have a higher fracture incidence following treatment completion.

18 Jan 2013

'Science Speaks' examines new Senate committee members' support for global health

The Center for Global Health Policy's "Science Speaks" blog profiles Sens. Barbara Mikulski (D-Md.), Patty Murray (D-Wash.), and Richard Shelby (R-Ala.), discusses their different committee appointments, and examines their support for global health initiatives.

18 Jan 2013

mTorc1 promotes growth of inflammation-associated colon and gastric cancers

Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex have the potential to be developed into a new treatment for these diseases.

18 Jan 2013

New rule sets 2013 as the time for small business to count staff size for health law

Health law implementation headlines include reports about how new regulatory guidance might impact small businesses. Also, prominent physicians call for the government to release regulations for the part of the law forcing drug and medical device makers to disclose financial ties to doctors.

18 Jan 2013

Stress in adolescence can cause severe mental illness in young adulthood

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence — a critical time for brain development — and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it.

18 Jan 2013

92% of voters surveyed favor U.S. support of WHO, Better World Campaign poll shows

A new poll released on Wednesday by the Better World Campaign (BWC) "found that 61 percent of voters see the WHO favorably and 92 percent say the United States should continue contributing money to the agency," The Hill's "Healthwatch" blog reports.

18 Jan 2013

Flu virus can essentially tell time: Research

Scientists have discovered that that the flu virus can essentially tell time, thereby giving scientists the ability to reset the virus' clock and combat it in more effective ways. According to researchers at the Icahn School of Medicine at Mount Sinai, the flu knows how much time it has to multiply, infect other cells, and spread to another human being. If it leaves a cell too soon, the virus is too weak. If it leaves too late, the immune system has time to kill the virus.

18 Jan 2013

Researchers disagree over ethics of HIV treatment clinical trial in Africa, Nature reports

Nature reports how "a potential breakthrough in the quest to prevent HIV and AIDS has collided with sensitivities about testing expensive drugs in poor parts of the world."

18 Jan 2013

Burnout can cause negative health effects in middle-aged working women

Emotional exhaustion and physical and cognitive fatigue are signs of burnout, often caused by prolonged exposure to stress. Burnout can cause negative health effects including poor sleep, depression, anxiety, and cardiovascular and immune disorders.

18 Jan 2013

WFP plans to reach 2.5M people in Syria as government expands list of local aid groups allowed to work in country

"The United Nations World Food Programme (WFP) plans to reach 2.5 million people inside Syria with food aid -- a million more than it is currently assisting -- now that the government has expanded the list of local partners it can work with, the agency's chief said" Wednesday, the U.N. News Centre reports.

18 Jan 2013

Race bias decreases similarities in the brain's representations of faces

Racial stereotypes have been shown to have subtle and unintended consequences on how we treat members of different race groups. According to new research published in Psychological Science, a journal of the Association for Psychological Science, race bias also increases differences in the brain's representations of faces.

18 Jan 2013

Researchers: Operating room checklists, good work environments for nurses help reduce errors, readmissions

Having step-by-step checklists on hand may help doctors and nurses manage emergencies in the operating room, a new study suggests. In situations when a person's heart stops beating on the operating table or a patient begins bleeding uncontrollably, those lists can save time and brainpower, researchers said.

18 Jan 2013

Boehringer Ingelheim initiates enrollment in Phase III IFN-free HCV trial

Today, Boehringer Ingelheim announced that the first patients have been enrolled in the company's pivotal Phase III interferon (IFN)-free hepatitis C (HCV) clinical trial programme, HCVerso.

18 Jan 2013

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive - and thus vulnerable - to a novel cancer stem cell-targeting drug currently under development.

18 Jan 2013

Lack or excess of CaM kinase II affects heart muscle cell stiffness

A certain enzyme, the CaM kinase II, keeps the cardiac muscle flexible. By transferring phosphate groups to the giant protein titin, it relaxes the muscle cells. This is reported by researchers led by Prof. Dr. Wolfgang Linke of the Institute of Physiology at the Ruhr Universität in the journal Circulation Research. In failing hearts, which don't pump enough blood around the body, the scientists found an overly active CaM kinase II.

18 Jan 2013

Rochester scientists propose new reason why acute myeloid leukemia is so difficult to cure

University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have a much slower metabolism than most other tumors cells.

18 Jan 2013

Intermountain Risk Score tool can predict mortality among trauma patients

A simple, inexpensive blood test performed on trauma patients upon admission can help doctors easily identify patients at greatest risk of death, according to a new study by researchers at Intermountain Medical Center in Salt Lake City.

18 Jan 2013

Enrollment complete in GlycoMimetics’ GMI-1070 Phase 2 study for sickle cell disease

GlycoMimetics, Inc. (GMI), a clinical-stage biotechnology company researching a new class of glycobiology-based therapies for a broad range of diseases, today announced that it has completed enrolling patients in its Phase 2 study of GMI-1070, its lead investigational drug candidate.

18 Jan 2013

Medical News

Medications often prescribed for PAH could affect heart health of treated patients

Blog features two posts on new NTD publications

ADT increases risk of fracture incidence after treatment completion in men with prostate cancer

'Science Speaks' examines new Senate committee members' support for global health

mTorc1 promotes growth of inflammation-associated colon and gastric cancers

New rule sets 2013 as the time for small business to count staff size for health law

Stress in adolescence can cause severe mental illness in young adulthood

92% of voters surveyed favor U.S. support of WHO, Better World Campaign poll shows

Flu virus can essentially tell time: Research

Researchers disagree over ethics of HIV treatment clinical trial in Africa, Nature reports

Burnout can cause negative health effects in middle-aged working women

WFP plans to reach 2.5M people in Syria as government expands list of local aid groups allowed to work in country

Race bias decreases similarities in the brain's representations of faces

Researchers: Operating room checklists, good work environments for nurses help reduce errors, readmissions

Boehringer Ingelheim initiates enrollment in Phase III IFN-free HCV trial

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

Lack or excess of CaM kinase II affects heart muscle cell stiffness

Rochester scientists propose new reason why acute myeloid leukemia is so difficult to cure

Intermountain Risk Score tool can predict mortality among trauma patients

Enrollment complete in GlycoMimetics’ GMI-1070 Phase 2 study for sickle cell disease

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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