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Oncogene-induced senescence could play a key role in future cancer therapy

Cell aging, or cellular senescence, has an important role in the natural physiological response to tumor development. Activated oncogenes are able to induce senescence, and recent findings have suggested that oncogene-induced senescence (OIS) could play a key role in future cancer therapy.

12 Dec 2012

AstraZeneca, Case Western Reserve initiate AZD5847 Phase 2a trial in TB

Case Western Reserve University School of Medicine and AstraZeneca, a global biopharmaceutical company, today announced the first patient enrolled in a Phase 2a trial to assess the effectiveness of AZD5847, a new test drug for patients with tuberculosis (TB), including patients with HIV co-infection.

12 Dec 2012

Low-cost concierge care, social media among changes in practice of medicine

News outlets examine trends such as doctors' use of social media to explore medical information and the growth of relatively low-cost concierge medicine, where patients may pay $50 a month for unlimited doctors' visits and calls.

12 Dec 2012

Physically active lifestyle associated with academic performance among school students

Middle school students who are more physically fit make better grades and outperform their classmates on standardized tests, according to a newly published study from a professor at the University of Tennessee, Knoxville.

12 Dec 2012

Medicaid contractors, government employees doing the same work, GAO says

The Medicaid program has government employees and contractors doing some of the exact same work, which is wasting government time and money, according to a new Government Accountability Office report released Monday.

12 Dec 2012

Edith and Peter O'Donnell Awards to recognize Texas researchers on Jan.17

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) is pleased to announce the recipients of the 2013 Edith and Peter O'Donnell Awards who will be honored during a banquet on Thursday, January 17, 2013, in conjunction with TAMEST's 10th Annual Conference at the Westin Galleria Hotel in Dallas.

12 Dec 2012

Examining Americans' health: Longer, but sicker, lives; Childhood obesity drops

A new report finds Americans may be living longer thanks to medical advances, but they may also be sicker. Meanwhile, childhood obesity may be dropping in several cities around the nation.

12 Dec 2012

Emotion helps us recognize words quicker and more accurately straight away

Does the emotion in our voice have a lasting effect? According to Annett Schirmer and colleagues from the National University of Singapore, emotion helps us recognize words quicker and more accurately straight away.

12 Dec 2012

Uganda's proposed anti-homosexuality legislation would inhibit health care access

The Center for Global Health Policy's "Science Speaks" blog examines the potential impacts of a proposed anti-homosexuality bill in Uganda, writing that the bill "would stand as an obstacle to both access to health care and to the ability of health care providers to even offer services," making prevention of "the bill's passage a matter of life and death, as well as of rights and dignity."

12 Dec 2012

Contact precautions reduce number of visits by healthcare workers and outside visitors

The prevention and control of healthcare-associated infections (HAIs) can help reduce patient morbidity and mortality, but a common prevention effort for patients with hard to treat infections known as contact precautions, can have positive and negative impacts on patient care.

12 Dec 2012

Innovation in immunization programs can mean better learning, sharing of information

In this Guardian "Global Development Professionals Network" blog post, Robert Steinglass, senior immunization adviser at John Snow, Inc., and immunization team leader for the USAID-funded Maternal and Child Health Integrated Program, writes about the importance of innovation to improving childhood immunization programs and health systems.

12 Dec 2012

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New research, presented this morning at the 54th Annual Meeting of the American Society of Hematology (ASH), has identified important associations between Plasmodium falciparum (Pf) malaria and endemic Burkitt Lymphoma (eBL) that may help researchers identify young children who are more susceptible to eBL.

12 Dec 2012

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Noting "multidrug-resistant organisms are showing up in top-flight hospitals" around the world, Carl Nathan, chair of the department of microbiology and immunology at Weill Cornell Medical College, writes in this New York Times opinion piece, "What makes the rapid loss of antibiotics to drug resistance particularly alarming is that we are failing to make new ones."

12 Dec 2012

Primary care physicians provide better care to patients with diabetes

Previous research has shown that patients without a consistent primary care physician (PCP) have worse outcomes than those who do, but little is known about why this is true. New research from Brigham and Women's Hospital (BWH) has brought to light the importance of the role of a primary care physician in a population of diabetes patients. Their findings are published in the December 10, 2012 issue of Diabetes Care.

12 Dec 2012

Report highlights 80 programs aimed at improving maternal, child health in developing world

"I'm inspired when I see the growing number and quality of health market innovations now emerging in the developing world," Gina Lagomarsino, a principal and managing director at Results for Development Institute (R4D), writes in the Bill & Melinda Gates Foundation's "Impatient Optimists" blog.

12 Dec 2012

Researchers decipher mechanism by which anophelin binds to thrombin

An international project lead by the Molecular and Cell Biology Institute of Porto University with the participation of researchers from IMIM (Hospital del Mar Medical Research Institute) has, for the first time ever, deciphered the mechanism by which a substance called anophelin binds to an enzyme (thrombin) involved in the process of blood coagulation.

12 Dec 2012

Acetazolamide plus autoCPAP may reduce insomnia and control sleep apnea at high altitudes

For individuals with obstructive sleep apnea traveling to higher altitudes (which may exacerbate symptoms), use of a combination therapy resulted in improvement in symptoms including reduced insomnia and better control of sleep apnea, according to a preliminary study published in the December 12 issue of JAMA.

12 Dec 2012

Kaiser Permanente grant to help Children's Oakland rebuild and modernize 100-year-old hospital

Children's Hospital & Research Center Oakland announced today a $5 million grant from Kaiser Permanente to benefit the 100-year-old, not-for-profit medical center's rebuild and modernization efforts. This contribution will make a profound impact in the community and the quality of care available to all children.

12 Dec 2012

Activated astrocytes could play a harmful role in Alzheimer's disease

A research team composed of University of Kentucky researchers has published a paper which provides the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease.

12 Dec 2012

Study identifies KNDy neurons as a likely control switch of hot flushes

Hot flushes affect millions of people, and not just women. Yet, it is still unclear what causes the episodes of temperature discomfort, often accompanied by profuse sweating.

12 Dec 2012

Medical News

Oncogene-induced senescence could play a key role in future cancer therapy

AstraZeneca, Case Western Reserve initiate AZD5847 Phase 2a trial in TB

Low-cost concierge care, social media among changes in practice of medicine

Physically active lifestyle associated with academic performance among school students

Medicaid contractors, government employees doing the same work, GAO says

Edith and Peter O'Donnell Awards to recognize Texas researchers on Jan.17

Examining Americans' health: Longer, but sicker, lives; Childhood obesity drops

Emotion helps us recognize words quicker and more accurately straight away

Uganda's proposed anti-homosexuality legislation would inhibit health care access

Contact precautions reduce number of visits by healthcare workers and outside visitors

Innovation in immunization programs can mean better learning, sharing of information

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Primary care physicians provide better care to patients with diabetes

Report highlights 80 programs aimed at improving maternal, child health in developing world

Researchers decipher mechanism by which anophelin binds to thrombin

Acetazolamide plus autoCPAP may reduce insomnia and control sleep apnea at high altitudes

Kaiser Permanente grant to help Children's Oakland rebuild and modernize 100-year-old hospital

Activated astrocytes could play a harmful role in Alzheimer's disease

Study identifies KNDy neurons as a likely control switch of hot flushes

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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