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Astellas, Ambit announce results from quizartinib Phase 2 study on acute myeloid leukemia

Astellas Pharma Inc. and Ambit Biosciences Corporation announced today that the results from a completed Phase 2 study with the investigational FLT3 inhibitor, quizartinib (AC220), as an oral monotherapy treatment regimen in patients with relapsed or refractory acute myeloid leukemia (AML) were presented at the 54th Annual Meeting of the American Society of Hematology (ASH).

11 Dec 2012

Studies examine current treatment standards for patients with clotting disorders

Studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH) examine current treatment standards for patients with clotting disorders in an effort to improve outcomes.

11 Dec 2012

Nature, nurture appear to be significant factors in early antisocial behaviors of adopted children

Both nature and nurture appear to be significant factors in early antisocial behaviors of adopted children, a Wayne State University researcher believes.

11 Dec 2012

Lotus Pharmaceutical submits generic Xenical ANDA with FDA

Lotus Pharmaceutical Company Inc. has confirmed its submission of Abbreviated New Drug Application for Orlistat capsules, a generic version of Xenical, to the US Food and Drug Administration (FDA).

11 Dec 2012

Cedars-Sinai first in Los Angeles County to achieve Comprehensive Stroke Center Certification

Cedars-Sinai is one of the first five medical centers in the nation and the first in Los Angeles County to achieve Comprehensive Stroke Center Certification from The Joint Commission and the American Heart Association/American Stroke Association.

11 Dec 2012

GeneTex to introduce new Histone H3 antibody

GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is set to launch a new antibody against phosphorylated Histone H3.

11 Dec 2012

Some stroke patients may benefit from cerebral angioplasty and stent placement

Some stroke patients may benefit from cerebral angioplasty and stent placement, according to a new study published online in the journal Radiology.

11 Dec 2012

New approach can reduce occupational health hazard risks in construction workers

"Some of the most pressing occupational health hazard risks in construction" are associated with masonry operations, asphalt roofing, and welding, wrote Deborah Young-Corbett in an article recently accepted by the Journal of Civil Engineering and Management.

11 Dec 2012

New coronavirus can infect cells from humans and bats alike

The SARS epidemic of 2002-2003 was short-lived, but a novel type of human coronavirus that is alarming public health authorities can infect cells from humans and bats alike, a fact that could make the animals a continuing source of infection, according to a study to be published in in mBio-, the online open-access journal of the American Society for Microbiology, on December 11.

11 Dec 2012

$UC Irvine researcher to evaluate astronauts' hip fracture risk from space travel$

UC Irvine researcher to evaluate astronauts' hip fracture risk from space travel

A UC Irvine researcher is part of a NASA effort to understand more about bone density loss during astronauts' lengthy stays aboard the International Space Station.

11 Dec 2012

Carbon nanotubes can help regulate chloride levels in nerve cells that contribute to neural injuries

A nanomaterial engineered by researchers at Duke can help regulate chloride levels in nerve cells that contribute to chronic pain, epilepsy, and traumatic brain injury.

11 Dec 2012

MR-Ultrasound fusion biopsy can diagnose prostate cancer

Ground-breaking research by a UCLA team of physicians and engineers demonstrates that prostate cancer can be diagnosed using image-guided targeted biopsy.

11 Dec 2012

Pomalidomide safe and effective in treating multiple myeloma

A new oral agent under review by the U.S. Food and Drug Administration (FDA) is safe and effective in treating relapsed and treatment-resistant multiple myeloma, according to a multicenter, Phase II study presented by Mount Sinai School of Medicine researchers at the American Society of Hematology (ASH) Annual Meeting. The meeting is taking place December 8-11, 2012 in Atlanta.

11 Dec 2012

Study finds high serum galectin-1 levels in Hodgkin lymphoma patients

Blood levels of an immunity-related protein, galectin-1, in patients with newly diagnosed Hodgkin lymphoma reflected the extent of their cancer and correlated with other predictors of outcome, scientists reported at the American Society of Hematology annual meeting.

11 Dec 2012

Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia

Updated results from a Phase Ib/II clinical trial indicates that a novel therapeutic agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other therapy.

11 Dec 2012

Traumatic brain injury incidence: an interview with Professor Valery Feigin

Traumatic brain injury can be defined as an injury to the brain due to mechanical forces. Mechanical forces usually include falls, car accidents, accidental forces from another person or animal. It also includes sports-related brain injuries.

11 Dec 2012

Text4baby initiative effective service for pregnant women

Following last week's mHealth Summit, the largest event of its kind where leaders focus on how wireless technology can improve health outcomes, text4baby announced results from the first randomized evaluation of its service. The largest mobile health initiative in the U.S., text4baby was found to be an effective service for pregnant women.

11 Dec 2012

Pfizer's PD0325901 experimental drug blocks untreatable NF1 tumors

Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).

11 Dec 2012

Janssen announces U.S. prescribing information update for EDURANT tablets

Janssen Therapeutics, Division of Janssen Products, LP, announced today that the U.S. Food and Drug Administration (FDA) has approved a prescribing information update for EDURANT (rilpivirine) tablets to include 96-week pooled data from the Phase 3 ECHO and THRIVE studies, which evaluated the efficacy and safety of EDURANT for the treatment of human immunodeficiency virus type 1 (HIV-1) in antiretroviral treatment-naive adults.

11 Dec 2012

Bolstering extracellulal matrix prevents skin aging

As we get older, the trillions of cells in our body do too. And like us, they become less resilient and able to weather the stress of everyday life. Our skin especially tells the tale of what's happening throughout our bodies.

11 Dec 2012

Medical News

Astellas, Ambit announce results from quizartinib Phase 2 study on acute myeloid leukemia

Studies examine current treatment standards for patients with clotting disorders

Nature, nurture appear to be significant factors in early antisocial behaviors of adopted children

Lotus Pharmaceutical submits generic Xenical ANDA with FDA

Cedars-Sinai first in Los Angeles County to achieve Comprehensive Stroke Center Certification

GeneTex to introduce new Histone H3 antibody

Some stroke patients may benefit from cerebral angioplasty and stent placement

New approach can reduce occupational health hazard risks in construction workers

New coronavirus can infect cells from humans and bats alike

UC Irvine researcher to evaluate astronauts' hip fracture risk from space travel

Carbon nanotubes can help regulate chloride levels in nerve cells that contribute to neural injuries

MR-Ultrasound fusion biopsy can diagnose prostate cancer

Pomalidomide safe and effective in treating multiple myeloma

Study finds high serum galectin-1 levels in Hodgkin lymphoma patients

Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia

Traumatic brain injury incidence: an interview with Professor Valery Feigin

Text4baby initiative effective service for pregnant women

Pfizer's PD0325901 experimental drug blocks untreatable NF1 tumors

Janssen announces U.S. prescribing information update for EDURANT tablets

Bolstering extracellulal matrix prevents skin aging

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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