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Tiotropium benefits patients with chronic obstructive pulmonary disease

In order to widen the narrowed airways in patients with chronic obstructive pulmonary disease (COPD), tiotropium bromide (tiotropium in brief) is one of the drugs available that can be prescribed for inhalation. The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined whether tiotropium offers a perceptible advantage to patients compared to a dummy medication (placebo) and to other COPD drugs.

12 Dec 2012

Low prices for life-saving products may increase perception of risk among consumers

Consumers assume their risk of getting a serious illness is higher when medications are cheaper because they believe that prices for life-saving products are based on need and not profit, according to a new study in the Journal of Consumer Research.

12 Dec 2012

Blocking myeloid-derived suppressor cells after lymphopenia improves adoptive T-cell therapy

Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells and Tregs (suppressors of anti-tumor activity) after total body irradiation had eliminated them. Blocking myeloid-derived suppressor cells and regulatory T-cell reconstitution improved adoptive T-cell therapy, an immunotherapy designed to suppress tumor activity.

12 Dec 2012

Drugs for Neglected Diseases receives UNITAID grant for paediatric HIV programme

The Drugs for Neglected Diseases initiative welcomes the announcement by UNITAID to grant up to USD 17.3 million to the organization for its paediatric HIV programme.

12 Dec 2012

U.N. officials call on Security Council, international community to tackle complex crisis in Sahel

"Top United Nations officials on Monday called on the Security Council and the wider international community to support efforts to develop an integrated strategy to tackle the complex and multifaceted crisis facing the Sahel region of West Africa," the U.N. News Centre reports.

12 Dec 2012

Patient philanthropy may result in ethical dilemmas for physicians

Physicians associated with "patient philanthropy" - financial donations from grateful patients to a medical institution - are concerned with how these contributions might affect their own behavior and attitudes, and how they might impact the doctor-patient relationship. A new study by Scott Wright, MD and Joseph A. Carrese, MD, MPH of Johns Hopkins University, and colleagues, explores this topic.

12 Dec 2012

Gestational age and size at birth affect risk of early diagnosis of esophagitis

Infants that are born preterm or with impaired growth have an increased risk of developing gastroesophageal reflux disease (GERD), possibly leaving them vulnerable to the development of esophageal adenocarcinoma later in life.

12 Dec 2012

Researchers shed new light on how salmonella bacteria cause infections

Researchers have found that the bacteria are able to change key cells that line the intestine, enabling the bugs to thrive.

12 Dec 2012

Final data from Aeterna Zentaris’ perifosine plus sorafenib Phase 2 study on lymphomas

Aeterna Zentaris Inc. today announced that final Phase 2 data demonstrated that the combination of perifosine, its oral AKT inhibitor, and sorafenib, was well tolerated by heavily pretreated patients with relapsed/refractory lymphomas.

12 Dec 2012

Capsules: A day of stark state differences on health exchanges; Eye experts: States should make vision care an exchange benefit

Now on Kaiser Health News' blog, Colorado Public Radio's Eric Whitney and News Service of Florida's Jim Saunders, working in collaboration with KHN and NPR, offered updates regarding their respective state's action on health exchanges: "Friday is the deadline for states to decide if they want to build and operate their own exchanges or have the federal government do it.

12 Dec 2012

Older adults with visually impairing eye disease limit their activities due to fear of falling

A new study published in Investigative Ophthalmology & Visual Science found that between 40 to 50 percent of older adults with visually impairing eye disease limit their activities due to a fear of falling. Vision scientists warn that this protective strategy puts seniors at risk for social isolation and disability.

12 Dec 2012

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

FibroGen, Inc., and Astellas Pharma Inc., announced today the initiation of the first clinical study in the Phase 3 clinical development program of FG-4592/ASP1517, an orally administered small molecule, for treatment of anemia associated with chronic kidney disease ("CKD") in patients not on dialysis and on dialysis, to support approval in the U.S. and Europe.

12 Dec 2012

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) announced that two UT Southwestern Medical Center researchers are among the four chosen for the 2013 Edith and Peter O'Donnell Awards.

12 Dec 2012

Clinical trial to examine AstraZeneca experimental drug against pulmonary tuberculosis

A clinical trial will examine an investigational drug's early bacteria-killing activity in patients newly diagnosed with drug-sensitive pulmonary tuberculosis.

12 Dec 2012

Viewpoints: Sen. Portman's Rx for deficit talks; Gerson says Obama needs to give Boehner political cover to make a deal

Washington needs to pursue structural reforms in the country's important but unsustainable entitlement programs and in an inefficient, outdated tax code. By doing so, lawmakers can responsibly avoid the immediate cliff while addressing the long-term fiscal crisis and spurring job creation.

12 Dec 2012

Autism associated with reductions in cellular adhesion molecules in the blood

A new study published in Biological Psychiatry suggests that autism is associated with reductions in the level of cellular adhesion molecules in the blood, where they play a role in immune function.

12 Dec 2012

Zucker Hillside Hospital celebrates opening of new $120 million inpatient pavilion

Zucker Hillside Hospital today celebrated the opening of a new 130,000-square-foot, $120 million inpatient pavilion. Constructed with the generous support of North Shore-LIJ Health System trustees Donald and Barbara Zucker and other donors, the 130,000-square-foot building will consolidate outdated living quarters dispersed across the psychiatric facility's campus, significantly improving the coordination of services and treatment along the continuum of care.

12 Dec 2012

SIRT6 protein may play a critical role in blocking cancer and controlling cellular metabolism

A new study sheds more light on how an anti-aging gene suppresses cancer growth, joint University of Michigan Health System and Harvard Medical School research shows.

11 Dec 2012

Study shows how osteocalcin plays a significant role in bone strength

A new study from engineering researchers at Rensselaer Polytechnic Institute shows, for the first time, how the little-understood protein osteocalcin plays a significant role in the strength of our bones. The findings could lead to new strategies and therapeutics for fighting osteoporosis and lowering the risk of bone fracture.

11 Dec 2012

Moximed commences KineSpring System clinical trial in knee osteoarthritis

Moximed, Inc. announced today that the KineSpring System, an implantable medical spring that works by unloading the weight on the diseased knee joint, has been successfully implanted in the first patient enrolled in its US clinical study, SOAR.

11 Dec 2012

Medical News

Tiotropium benefits patients with chronic obstructive pulmonary disease

Low prices for life-saving products may increase perception of risk among consumers

Blocking myeloid-derived suppressor cells after lymphopenia improves adoptive T-cell therapy

Drugs for Neglected Diseases receives UNITAID grant for paediatric HIV programme

U.N. officials call on Security Council, international community to tackle complex crisis in Sahel

Patient philanthropy may result in ethical dilemmas for physicians

Gestational age and size at birth affect risk of early diagnosis of esophagitis

Researchers shed new light on how salmonella bacteria cause infections

Final data from Aeterna Zentaris’ perifosine plus sorafenib Phase 2 study on lymphomas

Capsules: A day of stark state differences on health exchanges; Eye experts: States should make vision care an exchange benefit

Older adults with visually impairing eye disease limit their activities due to fear of falling

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

Clinical trial to examine AstraZeneca experimental drug against pulmonary tuberculosis

Viewpoints: Sen. Portman's Rx for deficit talks; Gerson says Obama needs to give Boehner political cover to make a deal

Autism associated with reductions in cellular adhesion molecules in the blood

Zucker Hillside Hospital celebrates opening of new $120 million inpatient pavilion

SIRT6 protein may play a critical role in blocking cancer and controlling cellular metabolism

Study shows how osteocalcin plays a significant role in bone strength

Moximed commences KineSpring System clinical trial in knee osteoarthritis

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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