Receptor function is multifaceted and it is therefore highly advantageous to monitor multiple aspects in live cells and in real-time. This includes ligand binding, secondary messenger coupling, recruitment of scaffolding proteins such as arrestins, internalization and trafficking. This webinar will detail the latest advances in microplate reader-based technologies to monitor receptor pharmacology, particularly using bioluminescence resonance energy transfer (BRET).
Kinetic Characterization of Covalent Inhibitors on the PHERAstar
A TR-FRET Approach to Measure the Kinetics of Ligand-Receptor Binding and Its Application of Fragment Screening
The Kinetics of Drug Binding
Real-Time Cell Health Assays Deliver Better Data with Less Effort
Defining Physiological Normoxia in Cultured Cells for Translation to Animal Models and Man
Real Time Detection of G-Protein Coupled Receptors in Living Cells
How to Perform Real-Time, Walk-Away, Cell Health Assays
Optimizing Sensitivity and Specifity in the RT- QUiC Assay
Enhanced Protein-Protein Interactions in Living Cells Using the NanoBRET Assay & CLARIOstar
Novel Haemoglobin Modifying Activity Discovered Through Screening T-VDAcv
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