In today's laboratories, the expectations for high-throughput analysis and diverse processes extend beyond simply moving from one sample to the next.
The InMotion™ autosampler series is designed to tackle these problems by offering a flexible, modular platform that maximizes production while taking up minimal space.
Whether a laboratory demands the basic automation of the Flex series, the high-capacity multi-row sampling of the Pro and Max models, or the advanced functionality of the KF Oven and PX series, these instruments are designed to get things moving.
This article examines how the InMotion series improves laboratory efficiency through three key pillars:
- Maximum productivity in minimal space
- Flexible and tailored workflows
- Multiparameter integration

Image Credit: Mettler Toledo - Titration
Multiparameter analysis in flavor and fragrance density, refractive index, and color in one run
Precision in quality control is critical in the competitive world of flavors and fragrances, as raw materials such as essential oils are high-value investments. METTLER TOLEDO's automated multiparameter system provides a quick and dependable alternative to time-consuming older methods such as gas chromatography.
Elevate quality assurance
The primary goal of this application is to provide unrivaled quality assurance for complex flavor and aroma combinations.
By evaluating physical properties like density, refractive index, and color at the same time, manufacturers can spot discrepancies and ensure batch-to-batch consistency, offering precise results in as little as five minutes per sample.
The system helps transform the quality control process into a simplified, automated operation that saves time and ensures accuracy with even the most expensive raw materials.
InMotion™: The heart of automation
The InMotion PX Autosampler is designed to maximize operating efficiency.
- Versatile sample handling: Using overpressure, the system handles samples with varying viscosities, including very volatile and extremely viscous.
- Superior cleanliness: The system's automatic washing technique eliminates carryover between samples, resulting in standard deviations of density and refractive index as low as 0.00001.

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Automated wine color determination for consistency in every glass
Maintaining high sample throughput while conforming to industry standards is becoming increasingly critical in food and beverage production. Automated systems can correctly assess wine color for quality control while guaranteeing that the results are properly documented and traceable.
Compliance through automation
To meet OIV standards, the winemaker evaluates tonality, brightness, and chromatism. METTLER TOLEDO's application specialists created a system using a UV5 Excellence spectrophotometer, an InMotion™ Autosampler, and an immersion probe from Hellma Analytics to simplify measurements.
LabX™ laboratory software controls the entire system and procedure. After the analyst loads the samples onto the InMotion rack, measurements are taken automatically. The software performs the analysis correctly and consistently on all samples, assuring conformance to the OIV standard.
Built-in computations now allow values for chromatic features to be retrieved from the samples' spectral profiles in seconds.

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Karl Fischer titration of LiB electrode materials using the InMotion KF oven autosampler
As lithium-ion batteries (LIBs) continue to fuel the global transition to electrification and decarbonization, guaranteeing their safety and performance is more important than ever. From portable devices to heavy-duty industrial transportation, the reliability of various energy sources is dependent on a single critical factor: perfect water content management.
The challenge
Residual water in the cathode and anode materials poses a quiet hazard to battery integrity. Even minor amounts of moisture can react with electrolyte salts to form hydrofluoric acid (HF), a highly corrosive chemical that destroys the cell, shortens life cycles, and jeopardizes safety.
To meet the rigorous standards of current battery research, water levels must be kept below 150 ppm.
Automated excellence with InMotion™
The InMotion KF Pro oven autosampler offers a streamlined, automated process for detecting water content in solid electrode materials.
InMotion technology removes moisture from sample flakes by heating them to 160 °C in sealed 10 mL vials, avoiding contamination of the titration cell. Optimize battery production and research with a system that prioritizes precision, automation, and long-term dependability.

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Simultaneous titration of duplicate acid/base content in non-aqueous solvents
In the fast-paced world of pharmaceutical and chemical manufacturing, time and accuracy are critical.
Increase sample throughput by titrating duplicate samples in parallel. Whether testing the purity of active chemicals like sodium ibuprofen or determining acid-base concentration in non-aqueous solvents, this procedure ensures results are delivered efficiently and precisely.
How InMotion™ transforms workflows
When configured with two towers, InMotion™ can handle two different workplaces simultaneously.
Using the innovative "Sync" function, the system flawlessly coordinates the two approaches, sending triggers between towers to ensure the analysis process is carried out in the correct order. In addition to titration, the InMotion™ system automates basic operations including cleaning and conditioning sensors in separate beakers.
The InMotion™ Autosampler works with high-performance equipment to provide industry-leading results.
- DGi116-solvent electrodes: Two specialized sensors developed for measurement in non-aqueous situations
- Analytical balance: Ensures precise weighing of samples for absolute accuracy
- LabX™ software: Enables automated workflow and centralized data management
- Advanced accessories: Dosing units and a PowerShower™ for efficient electrode washing

Image Credit: Mettler Toledo - Titration
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METTLER TOLEDO instruments are used in research, scientific, and quality control labs, amongst many others in the pharmaceutical, chemical, food, and cosmetics industries. They are a global market leader with the three instrument groups most frequently used in the laboratory, like balances, pipettes, and pH meters, and we are a pioneer in the field of Automated Chemistry.
METTLER TOLEDO industrial solutions cover the diverse steps in a host of manufacturing processes at many of the same customers served for the laboratory. Solutions range from receiving raw materials, in-line process control and end-of-line packaging control, to logistics and shipping. Increasingly, these solutions are fully integrated into the customer's IT environment, helping automate their workflows.
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