Bile News and Research

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Researchers identify cells responsible for maintenance and regeneration of liver

While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery.

26 Feb 2021

A practical guide to critical parameters in acute care testing

The acute care testing handbook is a practical guide to critical parameters in acute care testing such as pO2, lactate and troponin.

From Radiometer Medical 24 Feb 2021

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice.

15 Feb 2021

New research aims to explore functions of bile acids in the gut stem cell niche

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant piece of the puzzle.

12 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Cholangiocarcinoma (CCA) is considered as a diverse group of epithelial cancers characterized by poor outcomes. Cholangiocarcinoma can be divided into three types according to the original position: Intrahepatic Cholangiocarcinoma (ICC), Perihilar Cholangiocarcinoma (PCC), and Distal Extrahepatic Tumors (DET).

3 Feb 2021

Evolutionary history reveals the function of fish and human bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients.

2 Feb 2021

Newly-identified nutrient helps the gut recall prior infections and kill invading bacteria

Scientists studying the body's natural defenses against bacterial infection have identified a nutrient--taurine--that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn).

16 Jan 2021

Eating avocado as part of daily diet can help improve gut health, shows study

Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or "gut."

16 Dec 2020

Bilayered delivery system offers new solution for treating IBS-C patients

Patients suffering from irritable bowel syndrome with constipation (IBS-C) have long needed an upgrade in treatment.

9 Dec 2020

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

8 Dec 2020

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Innate immunity key to limiting viral load in COVID-19 cases

As the coronavirus disease 2019 (COVID-19) pandemic continues to cause many difficulties for public health authorities, research is ongoing to understand how the virus can cause fatal effects on those infected and thereby suggest effective preventive and therapeutic measures against it.

8 Nov 2020

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Persistent-poverty counties face high risk of cancer mortality

Residents of counties that experience persistent poverty face a disproportionately high risk of cancer mortality, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

30 Sep 2020

New polygenic risk score to help predict the odds of drugs causing liver damage

The ancient Romans studied the livers of sacrificial animals to read omens and make prophesies. Now researchers at Tokyo Medical and Dental University and Takeda-CiRA program along with a world-wide team of collaborators, have devised a polygenic risk score (PRS) based on liver genomics that can predict the likelihood of medications causing liver damage.

19 Sep 2020