Cancer Immunotherapy News and Research

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Engineered viruses and gene therapy halt tumor growth and extend survival in mice

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor destruction in aggressive cancer models.

2 Jun 2025

Dual-target CAR T cell therapy shrinks tumors in aggressive brain cancer

A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer.

1 Jun 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

BCG immunotherapy reprograms bone marrow to boost cancer defense

29 May 2025

Innovative technology simplifies T cell harvesting for cancer immunotherapy

CAR T cell immunotherapy, which uses a patient's own modified immune cells to find and destroy cancer cells, can produce dramatic results when treating blood cancers like lymphoma and leukemia and shows promise against solid tumors.

29 May 2025

University of Houston receives $3 million to set up a Cancer Immunotherapy Biomarker Core

As part of a $93 million grant package, the Cancer Prevention and Research Institute of Texas, known for funding groundbreaking projects, has awarded the University of Houston $3 million to set up a Cancer Immunotherapy Biomarker Core.

27 May 2025

Age-related immune decline reduces CAR-T cell therapy efficacy

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.

20 May 2025

Immune checkpoint inhibitors linked to increased myocarditis risk in lung cancer patients

A new editorial was published in Volume 12 of Oncoscience on May 2, 2025, titled "Immune checkpoint inhibitors and myocarditis: Lessons from a nationwide cohort study."

16 May 2025

Researchers identify key cells behind peanut allergy prevention

A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts.

15 May 2025

Revolutionary incision-free technique halts growth of brain cavernomas

A new, incision-free technique developed at UVA Health to treat debilitating brain lesions called cerebral cavernous malformations, or cavernomas, has shown great promise in early testing, halting the growth of the lesions almost entirely.

15 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Next-generation "armored" CAR T cell therapy shows promising results in lymphoma patients

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially available CAR T cell therapies.

8 May 2025

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses.

28 Apr 2025

New topical gel reduces painful rash from colorectal cancer treatment

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer.

28 Apr 2025

Bruker to launch Beacon Discovery™ at AACR 2025, expanding access to live single-cell functional analysis

Bruker Corporation today announced the launch of the Beacon Discovery™ Optofluidic System at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2025.

From Bruker Cellular Analysis 25 Apr 2025

Novel cancer immunotherapy approach could complement existing CAR-T treatments

Researchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric Antigen Receptor T-cell) treatments.

24 Apr 2025

Cancer immunotherapy effective across all ages despite immune differences

Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, and the Johns Hopkins Convergence Institute.

21 Apr 2025

UVA scientist secures funding to use sound waves for breast cancer therapy

University of Virginia researcher Natasha D. Sheybani, PhD, has received $5.5 million from the federal Department of Defense to support her cutting-edge efforts to use focused sound waves to improve our immune system's ability to battle breast cancer.

15 Apr 2025

Inherited genetic variants play crucial role in cancer development and behavior

A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with-known as germline genetic variants-play a powerful, underappreciated role in how cancer develops and behaves.

15 Apr 2025

UVA researcher wins major grant to revolutionize breast cancer treatment

A promising approach to achieve safer, more effective, and more precise breast cancer treatment has earned a University of Virginia researcher a new $5.5 million grant.

11 Apr 2025

Cancer Immunotherapy News and Research

Engineered viruses and gene therapy halt tumor growth and extend survival in mice

Dual-target CAR T cell therapy shrinks tumors in aggressive brain cancer

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

BCG immunotherapy reprograms bone marrow to boost cancer defense

Innovative technology simplifies T cell harvesting for cancer immunotherapy

University of Houston receives $3 million to set up a Cancer Immunotherapy Biomarker Core

Age-related immune decline reduces CAR-T cell therapy efficacy

Immune checkpoint inhibitors linked to increased myocarditis risk in lung cancer patients

Researchers identify key cells behind peanut allergy prevention

Revolutionary incision-free technique halts growth of brain cavernomas

CAR-T cell therapy linked to brain fog in cancer patients

Next-generation "armored" CAR T cell therapy shows promising results in lymphoma patients

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

New topical gel reduces painful rash from colorectal cancer treatment

Bruker to launch Beacon Discovery™ at AACR 2025, expanding access to live single-cell functional analysis

Novel cancer immunotherapy approach could complement existing CAR-T treatments

Cancer immunotherapy effective across all ages despite immune differences

UVA scientist secures funding to use sound waves for breast cancer therapy

Inherited genetic variants play crucial role in cancer development and behavior

UVA researcher wins major grant to revolutionize breast cancer treatment

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