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Research reveals 36% higher heart defect risk in IVF babies

The risk of being born with a major heart defect is 36% higher in babies who were conceived after assisted reproductive technology, such as in vitro fertilization (IVF), according to results of a very large study published in the European Heart Journal today (Friday).

26 Sep 2024

Molecular pathways in human cells reveal potential for developmental pause

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother.

26 Sep 2024

PRP intraovarian injection improves the number and quality of blastocysts in mouse models

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 13, 2024, entitled, "Intraovarian PRP injection improves oocyte quality and early embryo development in mouse models of chemotherapy-induced diminished ovarian reserve."

24 Sep 2024

The role of CRISPR-Cas9 in combating mosquito-borne diseases

Announcing a new article publication for Zoonoses journal. As global warming increases, mosquito activity areas are expanding, alongside changes in the natural environment and the misuse of insecticides, thus further increasing mosquito resistance and exposing the world to an elevated risk of mosquito-borne diseases.

23 Sep 2024

High altitude linked to increased congenital heart disease in women

The global prevalence of congenital heart disease is higher among women who live in high altitudes, according to a new study being presented at ACC Latin America 2024 in Punta Cana, Dominican Republic.

18 Sep 2024

Newly discovered mechanism could revolutionize infertility care by promoting embryo implantation

A team from Kumamoto University has uncovered a new mechanism that could revolutionize infertility care by promoting embryo implantation.

18 Sep 2024

Discovery of 5-formylcytosine as an activating epigenetic switch

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development.

18 Sep 2024

NIH funds study on environmental impact on male fertility

A grant from the National Institutes of Health will support ongoing research at Wayne State University investigating the consequences environmental factors may have on fertility in males.

18 Sep 2024

IVF transfer day does not impact overall success rates, study reveals

In IVF treatment, embryos are traditionally transferred in the uterus three days after fertilization. Due to improvements in laboratory techniques, this is now also possible after five days.

17 Sep 2024

Unveiling the mechanism behind DNA organization in early embryos

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos.

16 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Early embryos are prone to chromosomal copying errors, new research shows

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication.

28 Aug 2024

Study identifies genetic cause of severe seizures in children

Shortly after Kelly Cervantes' daughter Adelaide was born, she started having terrible seizures. Doctors were unable to give her a solution, or even a cause.

28 Aug 2024

Improved IVF success with the Mediterranean diet, study shows

Review highlights that adherence to the Mediterranean diet may improve clinical pregnancy and live birth rates in couples undergoing assisted reproduction, though findings are inconsistent, and more research is needed.

27 Aug 2024

Inflammation during pregnancy impacts child neurodevelopment

When a person experiences an injury or infection, the body's immune system responds with inflammation to start the healing process. However, inflammation can occur in much less helpful circumstances – for example, when a person experiences psychological stress or consistently eats a poor diet high in sugars, fats, and processed foods.

9 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

Triploidy causes 42% of early miscarriages in horses

A study of horses – which share many important similarities with humans in their chromosomes and pregnancies – revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy were due to complications from an extra set of chromosomes, a condition called triploidy.

5 Aug 2024

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Their findings are published in the journal Cell Reports Medicine.

27 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego - a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Before Michigan legalized surrogacy, families found ways around the ban

The first time Tammy and Jordan Myers held their twins, the premature babies were so fragile that their tiny faces were mostly covered by oxygen masks and tubing.

16 Jul 2024