Gliomas News and Research

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Study finds potential new therapeutic targets for childhood brain tumors

People with the genetic condition neurofibromatosis type 1 (NF1) are prone to developing tumors on nervous system tissue.

2 May 2020

AI may help eliminate use of biopsy for brain cancer patients

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

21 Apr 2020

Real-time imaging reveals how infiltrating glioma cells alter brain function, blood flow

The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor.

15 Apr 2020

Good news for patients with NFI-related low grade gliomas

A paper published in the academic journal Neuro-Oncology by NF experts has demonstrated an increased understanding of low grade gliomas (LGG) occurring in children and adults with NF1.

1 Apr 2020

Simple blood test could be used by GPs to aid in earlier brain tumor diagnosis

A new simple blood test for brain tumors that could be used by GPs in primary care is being developed thanks to funding of nearly £500,000 by Cancer Research UK.

24 Feb 2020

Combination therapy for pediatric low-grade gliomas shows promise in mice

In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas.

17 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

Protein linked with neurodegenerative diseases may help explore the aggressive behavior of gliomas

A protein typically associated with neurodegenerative diseases like Alzheimer's might help scientists explore how gliomas, a type of cancerous brain tumor, become so aggressive.

22 Jan 2020

Researchers identify new pathway as biological target for colon cancer

Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease.

13 Jan 2020

Surgical removal of tumor may boost survival of patients with brainstem high-grade gliomas

For adult patients with brainstem high-grade gliomas -- one of the rarest and deadliest forms of brain cancer -- surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemotherapy, according to results of a medical records study led by researchers at the Johns Hopkins Kimmel Cancer Center.

From Johns Hopkins Medicine 9 Jan 2020

Nature’s own gene therapy

A brand-new technique of gene therapy was reported on December 16, 2019, in the journal Nature Biomedical Engineering. The scientists made use of the potential of human cells to produce biological nanoparticles chockful of edited genes, so that they could insert beneficial genes into people suffering from various disease processes.

17 Dec 2019

New gene therapy has potential to reverse disease processes

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

17 Dec 2019

Researchers discover cellular origins of pediatric brain tumors

A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre, and Dr. Michael Taylor, of The Hospital for Sick Children, discovered that several types of highly aggressive and, ultimately, fatal pediatric brain tumors originate during brain development.

25 Nov 2019

Scientists investigate the dynamics of molecular changes in gliomas

Until relatively recently, cancer was viewed as a single disease with sub-types based on where in the body it arose.

22 Nov 2019

Researchers identify a promising drug pair to attack deadly childhood brain cancers

Researchers have devised a new plan of attack against a group of deadly childhood brain cancers collectively called diffuse midline gliomas, including diffuse intrinsic pontine glioma, thalamic glioma and spinal cord glioma.

20 Nov 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Fluorescent tags help diagnose and monitor brain gliomas more effectively

A new study published online in the journal eBioMedicine on October 15, 2019, describes the use of an orally ingested agent called 5-aminolevulinic acid (5-ALA) to confirm the diagnosis of the aggressive brain tumor called glioma.

16 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

UC experts explore if ketogenic diet could help make treatments for glioblastoma

Investigators at the University of Cincinnati are studying whether or not a modified Atkins-type ketogenic diet could help make treatments for a common, but dangerous, type of brain cancer called glioblastoma more effective.

30 Sep 2019