Hepatitis B Virus News and Research

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Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

A new study identified the gut microbial and immune variables linked to heterogeneous messenger ribonucleic acid (mRNA) COVID-19 vaccine responses between individuals.

11 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

Inexpensive, self-driven microfluidic chip rapidly detects Hepatitis C virus in about 45 minutes

Hepatitis C affects more than 354 million people worldwide. About 75 to 85 percent of people who have it get a long-term infection referred to as chronic Hepatitis C. Left untreated, it could lead to cirrhosis, liver cancer or liver failure.

3 Aug 2022

NIH updates its strategic plan for hepatitis B research

The National Institutes of Health has updated its Strategic Plan for NIH Research to Cure Hepatitis B, a roadmap for ending the hepatitis B epidemic, focused on developing a cure as well as improved strategies for vaccination, screening and follow-up care.

1 Aug 2022

World Hepatitis Day 2022: Why Accelerating the Fight Against Hepatitis Cannot Wait

In our latest interview, News-Medical speaks to Simon Parker, an infectious disease specialist, about hepatitis C diagnostics and testing, as well as why the global fight against hepatitis cannot wait.

28 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data

A new study compares and assesses eight de novo genome assembly software tools on actual viral next-generation sequencing data.

20 Jul 2022

Combinations of broadly neutralizing antibodies may be a more effective approach to treat HIV

Carefully designed cocktails of broadly neutralizing antibodies (bNAbs) could help treat HIV while minimizing the risk of the virus escaping treatment, suggests a study published today in eLife.

20 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Chemically modified rocaglates have a stronger effect against viral replication

Hepatitis E virus (HEV) is widespread, and so far there is no effective drug. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses.

27 Jun 2022

The potential role of Ginkgo biloba L. folium extract in the management of COVID-19

Researchers explored the effectiveness of Ginkgo biloba L. folium extract (EGb) in the management of COVID-19 severity.

13 Jun 2022

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

26 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Racism may partly contribute to high cancer burden impacting Asian Americans

The Journal of the National Cancer Institute published a commentary today on the significant cancer disparities facing Asian Americans.

19 Apr 2022

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Researchers reviewed non-viral nano-vectors used for delivering the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated genome editing system.

14 Apr 2022