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Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics.

14 Sep 2023

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Researchers identified diabetic individuals among populations with normal fasting glucose using ML.

12 Sep 2023

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

The hematological parameters and serum biomarkers of inflammation and immunity in patients with atopic dermatitis and psoriasis.

12 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Scientists discover thymic M cells

It came as a surprise to Professor David Lo and his graduate student Diana Del Castillo when they were recently consulted by researchers in Israel for their expertise on specialized cells called Microfold cells, or M cells, which are mostly known for their presence in the intestinal epithelium.

7 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Study explores the biology of post-COVID-19 cognitive deficits

Researchers explored the biology of cognitive deficits following acute COVID-19.

4 Sep 2023

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned.

30 Aug 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Gut dysbiosis among critically ill individuals

16 Aug 2023

CT imaging reveals that COVID-19 vaccination may protect against severe lung pathology

Researchers determine how COVID-19 vaccination influences lung-sequelae-related pathology and the manifestation of severe infection.

9 Aug 2023

The immune-modulatory effect of lenvatinib investigated in new study

Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.

9 Aug 2023

Outcome markers in COPD patients with COVID-19

Researchers identify potential markers for severe COVID-19 and death in COPD patients.

8 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

The immunomodulatory and antiviral function of vitamin D

Vitamin D's immunomodulatory and antiviral function.

4 Aug 2023

Study assesses the value of predictive biomarkers for early-stage COVID-19 infection

Researchers illustrated that certain biomarkers may be better predictors of COVID-19 than others.

2 Aug 2023

Lymphocyte News and Research

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Reviving reservoirs: new findings shake up HIV treatment understanding

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Scientists discover thymic M cells

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Study explores the biology of post-COVID-19 cognitive deficits

Gene variant protects against Alzheimer's and Parkinson's diseases

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

CT imaging reveals that COVID-19 vaccination may protect against severe lung pathology

The immune-modulatory effect of lenvatinib investigated in new study

Outcome markers in COPD patients with COVID-19

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

The immunomodulatory and antiviral function of vitamin D

Study assesses the value of predictive biomarkers for early-stage COVID-19 infection

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