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Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected by the condition.

9 Apr 2025

Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

9 Apr 2025

Neuropathological basis of visual dysfunction in rare Alzheimer's forms

Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer's disease, finds a new study by UCL researchers.

3 Apr 2025

Researchers uncover mechanism linking maternal inflammation to delayed neurodevelopment in infants

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking maternal inflammation to delayed neurodevelopment in infants.

1 Apr 2025

Blocking an inflammatory receptor in the retinas of aging mice improves retinal health

A new research paper was published in Aging (Aging-US) on January 31, 2025, in Volume 17, Issue 2, titled "Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice."

25 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Understanding the role of CD2AP in Alzheimer's disease

A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide.

19 Mar 2025

Study sheds light on why women experience chronic pain more than men

A new study led by University of Calgary professor Dr. Tuan Trang, PhD, may help to explain why there is an over-representation of women experiencing chronic pain compared to men.

18 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

For more than three decades, scientists have been racing to stop Alzheimer's disease by removing amyloid beta plaques - sticky clumps of toxic protein that accumulate in the brain.

6 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Scientists uncover how herpes virus fuels Alzheimer’s disease

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

2 Mar 2025

Nasal spray may offer new hope for traumatic brain injury patients

A new study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI).

27 Feb 2025

UCLA scientists discover new approach for treating glioblastoma

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.

26 Feb 2025

Research highlights gender and age differences in eye gene therapy responses

Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found.

10 Feb 2025

Researchers discover strategy to slow brain metastases growth in melanoma

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) in Elche, have identified a strategy to slow their progression, which could improve the response to current treatments.

7 Feb 2025