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Cycles of fasting-mimicking diet appear to reduce signs of Alzheimer’s in mice

Cycles of a diet that mimics fasting appear to reduce signs of Alzheimer's in mice genetically engineered to develop the illness, according to a new USC Leonard Davis School of Gerontology-led study.

27 Sep 2022

Research reveals the role of microglia-neuron connections during brain development

The Laboratory of Neuroimmunology of the Institute of Experimental Medicine, Budapest, Hungary, led by Ádám Dénes, describes the presence of a direct interaction site between microglial cells and the cell body of developing neurons, and reveals its role during brain development.

20 Sep 2022

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Researchers explored the effect of SARS-CoV-2 exposure on the brain.

20 Sep 2022

Scientists develop and test a new model of traumatic brain injury in zebrafish

A group of scientists, which included researchers from the Ural Federal University (UrFU), have developed and successfully tested a new model of traumatic brain injury (TBI) in zebrafish.

15 Sep 2022

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston.

8 Sep 2022

Understanding how microglia change their states to adapt to different areas of the brain

In this interview, News Medical speaks to Jeffrey Stogsdill, Ph.D., about his latest research exploring how microglia change their state to adapt to different areas of the brain.

2 Sep 2022

Study reveals clues what makes the human brain distinct from others

What makes the human brain distinct from that of all other animals -; including even our closest primate relatives? In an analysis of cell types in the prefrontal cortex of four primate species, Yale researchers identified species-specific -; particularly human-specific -; features, they report Aug. 25 in the journal Science.

26 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

Scientists unravel the development of main immune cell population residing in the brain

New research published today by the University of Southampton shows new insight in how our brain develops, that can pave the way for treating neurological disorders.

16 Aug 2022

Researchers engineer artificial replicas of G protein-coupled receptors

How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors are so-called G protein-coupled receptors, or in short GPCRs.

15 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (Aβ), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease Aβ plaque burden in AD patients, its effect on cognitive improvement is still controversial.

4 Aug 2022

Microglia News and Research

Cycles of fasting-mimicking diet appear to reduce signs of Alzheimer’s in mice

Research reveals the role of microglia-neuron connections during brain development

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Scientists develop and test a new model of traumatic brain injury in zebrafish

Age-related changes in microbiome composition affects brain macrophages

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

Understanding how microglia change their states to adapt to different areas of the brain

Study reveals clues what makes the human brain distinct from others

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

Scientists unravel the development of main immune cell population residing in the brain

Researchers engineer artificial replicas of G protein-coupled receptors

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

The aging human brain

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Nanoparticles' toxic effects on macrophages

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

How COVID-19 affects the brain microvasculature

Alzheimer's disease and anti-amyloid therapeutic approaches

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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