Natural Killer Cells News and Research

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Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

New findings published Dec. 9 in Nature Biomedical Engineering from scientists at Fred Hutchinson Cancer Research Center show for the first time that a piece of small, thin metal mesh loaded with cancer-fighting immune cells shrinks tumors in preclinical models of ovarian cancer.

9 Dec 2019

Young patients with IBD have increased risk of severe viral infections

Young patients with inflammatory bowel disease are five times more likely than the general population to develop viral infections that can lead to hospitalization or permanent organ damage, a new study published in the UEG Journal has found.

5 Dec 2019

Transitional T cells could help improve cancer immunotherapy

In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted, there is a transitory stage in which some cells are present with features that are characteristic of neither the stem-like T cells nor the mature but exhausted T cells.

4 Dec 2019

SDSU researchers show cancer-inhibiting potential of flavonoid metabolite

Eating fruits and vegetables is more important than ever.

2 Dec 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Researchers discover new process of antitumor response of NK cells in myeloma

NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although evidence about their antitumoral capacity, how this activity occurred remained unknown.

5 Nov 2019

Fetal gut has more well-developed immune capabilities than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh challenges that paradigm, and provides the first comprehensive look at the immune system of the developing gut.

10 Oct 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Mount Sinai awarded $1.7 million to study how bladder cancer affects 'natural killer' cells

The Icahn School of Medicine at Mount Sinai has been awarded nearly $1.7 million in grant funding from the U.S. Department of Defense to study how bladder cancer affects certain types of white blood cells called "natural killer" cells, or NK cells, which control and limit tumor growth.

12 Sep 2019

Researchers analyze people’s initial immune response to dengue fever

Researchers have come one step closer to understanding how our immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone.

29 Aug 2019

UC San Diego researchers identify new therapeutic approach to kill cancer cells

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic.

22 Aug 2019

New insight into the immune system may help doctors to better fight cancer

Your immune system's natural killer cells recognize and attack two major kinds of danger - cells infected by viruses and cells affected by cancer.

20 Aug 2019

Study shows how 'natural-killer' cells may help women avoid placental accreta

One of the most dangerous risks expectant mothers face as their delivery date approaches is a surprisingly common condition with a little-known name: placental accreta.

5 Aug 2019

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States.

29 Jul 2019

Scientists discover novel mechanism of action for NK cells in checkpoint inhibitor for cancer

PD-L1 checkpoint inhibitors are a powerful and growing form of immunotherapy used to treat melanoma, kidney cancer, head and neck cancers, Hodgkin's lymphoma and other cancers.

27 Jul 2019

Cancer stem cells elude the body's immune cells by deactivating danger detector

Acute myeloid leukemia stem cells elude the body's immune cells by deactivating a danger detector. The underlying mechanisms and the potential new therapeutic approaches that this gives rise to have been detailed in the journal Nature by researchers from the University of Basel and University Hospital Basel in collaboration with colleagues in Germany.

18 Jul 2019

Virus employs powerful strategy to inhibit natural killer cell function

The virus responsible for chickenpox and shingles employs a powerful strategy of immune evasion, inhibiting the ability of natural killer cells to destroy infected cells and produce molecules that help control viral infection, according to a study published June 13 in the open-access journal PLOS Pathogens by Allison Abendroth of the Discipline of Infectious Diseases and Immunology in the Charles Perkins Centre at the University of Sydney, and colleagues.

From PLOS ONE 14 Jun 2019

Researchers gain insight into possible origins of 'ancient' immunological memory

Natural killer cells are part of the innate immune system. Their role is to detect virus-infected cells and destroy them.

4 Jun 2019

CU Anschutz researchers identify new immunodeficiency disease

A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers at the University of Colorado Anschutz Medical Campus providing unique insights into cell biology.

6 May 2019