Transcriptomics News and Research

RSS

TraMA offers breakthrough in measuring biological age

A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled "Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA)."

28 Jul 2025

Advancing precision medicine in colorectal cancer with multi-omics approaches

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

28 Jul 2025

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

In a comprehensive Genomic Press interview published in Brain Medicine today, Dr. Hamilton Se-Hwee Oh reveals groundbreaking insights into the complex dialogue between our brains and bodies that fundamentally shapes aging, depression, and neurodegenerative disease.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

Developing AI-driven stem cell therapies to fight ovarian aging

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

18 Jul 2025

Intratumoral microbiota reshape our understanding of cancer biology

Intratumoral microbiota-the microbial populations residing within solid tumors-have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and therapeutic outcomes.

18 Jul 2025

New biomarker ELL2 identified for early diagnosis and prognosis in sepsis

Sepsis is a life-threatening condition caused by organ dysfunction resulting from the body's dysregulated response to infection.

18 Jul 2025

ANXA2 positive hepatocytes drive migration based repair in acute liver failure

Acute liver failure (ALF) represents a life-threatening condition marked by rapid deterioration of liver function, often necessitating urgent liver transplantation.

18 Jul 2025

Extracellular vesicle RNA reveals clues about obesity and metabolic disease

Our study examines how RNA in extracellular vesicles (EVs) can provide insights into metabolic phenotypes related to obesity. By using functional genomics approaches, we found a high representation of genes and regulatory elements previously associated with obesity and type 2 diabetes represented by the RNA cargo within these EVs.

15 Jul 2025

NIH awards major grant to advance mucormycosis research

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA (TLI) announced today that the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a new grant (P01AI186818) to Dr. Ashraf S. Ibrahim, PhD, a TLI Investigator, a Professor of Medicine at David Geffen School of Medicine at UCLA, and a leading authority on mucormycosis pathogenesis.

15 Jul 2025

Protein signatures may help predict malaria severity and guide treatment

Researchers at Karolinska Institutet have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.

14 Jul 2025

Dual targeting of lipid kinases offers hope against emerging viruses

Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid molecules in the body.

14 Jul 2025

Weight loss wipes out senescent fat cells but leaves immune scars, study finds

Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

10 Jul 2025

Oral lysozyme can restore healthy gut balance and reverse signs of vascular aging

A study reveals that lysozyme (LYZ) plays a pivotal role in age-related blood vessel inflammation by influencing gut bacteria.

8 Jul 2025

Aspartame triggers genetic changes tied to glioblastoma severity

Study shows aspartame affects gut microbiome and gene expression in glioblastoma, highlighting potential links to cancer progression and treatment strategies.

8 Jul 2025

Intelligent, Scalable, Precise: How n6 Is Transforming NGS Library Prep

In this interview, the team at n6 discusses their groundbreaking iconPCR thermocycler and its impact on laboratory automation, NGS data quality, and real-time control in life sciences.

From n6 7 Jul 2025

New insights into nature's most remarkable innovation- the ability to sustain a successful pregnancy

An international research team led by scientists from the University of Vienna has uncovered new insights into how specialized cell types and communication networks at the interface between mother and fetus evolved over millions of years.

4 Jul 2025

Blocking key immune cells could make prostate cancer treatable

Scientists have revealed how certain immune cells may be quietly helping prostate cancer grow - and how blocking them could help the body fight back.

3 Jul 2025

New cutting-edge software can help uncover hidden features of childhood heart tumors

New cutting-edge software developed in Melbourne can help uncover how the most common heart tumour in children forms and changes.

1 Jul 2025

Cannabis smoking changes your DNA, leaving epigenetic scars

Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic footprint on blood DNA. These methylation changes strongly overlap with those from tobacco and may serve as biomarkers of smoke exposure.

30 Jun 2025