Tumorigenesis News and Research

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Tumorigenesis is the process involved in the production of a new tumor or tumors.

Researchers discover potential hurdle for personalized medicine

A recent study has shown that loss of the Erk oncogene can stimulate tumorigenesis in cells where Ras has been eliminated. The findings may have important consequences for the development of personalized medicines that target Ras.

17 Apr 2018

Live-cell imaging capabilities of the InVi SPIM microscope announced by Luxendo

Luxendo, a Bruker company, today announced the extension of the InVi SPIM microscope to include full incubation capabilities, as well as flexible illumination and detection optics.

From Bruker 28 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Epigenetic changes due to normal aging process linked to cancer risk

Some scientists have hypothesized that tumor-promoting changes in cells during cancer development--particularly an epigenetic change involving DNA methylation--arise from rogue cells escaping a natural cell deterioration process called senescence.

22 Feb 2018

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.

24 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Molecule plays double role in maintaining gut health and promoting diseases

A molecule that controls intestinal cell growth plays a dual role maintaining gut health and promoting diseases such as cancer, says a study in eLife.

30 Nov 2017

KAIST researchers identify principles of gene network for colon tumorigenesis

The principles of the gene network for colon tumorigenesis have been identified by a KAIST research team. The principles will be used to find the molecular target for effective anti-cancer drugs in the future. Further, this research gained attention for using a systems biology approach, which is an integrated research area of IT and BT.

20 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

A human gene called p53, which is commonly known as the "guardian of the genome," is widely known to combat the formation and progression of tumors. Yet, mutant forms of p53 have been linked to more cases of human cancer than any other gene.

19 Oct 2017

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

22 Sep 2017

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC.

14 Sep 2017

Impaired DNA replication may lead to trans-generational inheritance of epigenetic changes

Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations.

17 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Tumorigenesis News and Research

Researchers discover potential hurdle for personalized medicine

Live-cell imaging capabilities of the InVi SPIM microscope announced by Luxendo

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Epigenetic changes due to normal aging process linked to cancer risk

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Molecule plays double role in maintaining gut health and promoting diseases

KAIST researchers identify principles of gene network for colon tumorigenesis

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

Impaired DNA replication may lead to trans-generational inheritance of epigenetic changes

Counteracting premature aging

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Research reveals role of Rrm3 protein in repair of breaks that occur during DNA replication

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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