Bladder News and Research

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Findings could help explain prevalence of urinary tract infections in post-menopausal women

Researchers from Washington University School of Medicine, St. Louis, show that reservoirs of uropathogenic E. coli within the bladder exist in higher numbers post-menopause than pre-menopause in a mouse model, a finding that could help explain the greater prevalence of urinary tract infections in post-menopausal women.

25 Jan 2013

Sacral nerve stimulation helps manage children with chronic incontinence

Incontinence is typically a condition associated with adults; however, many children also struggle with incontinence - bladder, bowel or both. In order to help these children, doctors at Nationwide Children's Hospital have turned to a device, typically used in adult patients, to help manage children with chronic incontinence.

24 Jan 2013

Boosting estrogen levels may help reduce urinary infections in menopausal women

Estrogen levels drop dramatically in menopause, a time when the risk of urinary tract infections increases significantly.

24 Jan 2013

Bladder cancer risk associated with childbearing factors

The risk for bladder cancer in women may decline with increased parity and older age at first birth, researchers report.

21 Jan 2013

FDA approves Allergan’s BOTOX to treat overactive bladder

Allergan, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved BOTOX (onabotulinumtoxinA) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency in adults who have had an inadequate response to or are intolerant of an anticholinergic medication.

19 Jan 2013

SPARC protein acts much like ibuprofen to heal tissues inflamed by tumors

Cancer researchers are increasingly aware that in addition to genetic mutations in a cancer itself, characteristics of the surrounding tissue can promote or suppress tumor growth. One of these important tissue characteristics is inflammation - most cancers prosper in and attach to inflamed tissue and so many cancers have developed ways to create it.

19 Jan 2013

Allergan receives FDA approval for Botox to treat overactive bladder

The U.S. Food and Drug Administration today expanded the approved use of Botox (onabotulinumtoxinA) to treat adults with overactive bladder who cannot use or do not adequately respond to a class of medications known as anticholinergics.

18 Jan 2013

Scientists identify new mechanism for schistosomiasis-bladder cancer connection

About 200 million people across 75 of the poorest countries in the world are now infected by the blood parasite Schistosoma haematobium (S. haematobium). The infection causes severe urogenital disease, but also causes bladder cancer in a number of patients and why this occurs is not clear.

17 Jan 2013

Link between smoking intensity and bladder cancer prognosis

Smoking not only causes bladder cancer-it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

16 Jan 2013

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Increased NEK2 gene expression linked to increased drug resistance, faster cancer growth, and poorer patient outcome - The finding may improved diagnostic and prognostic tools for cancer care and could lead to improved cancer therapies

16 Jan 2013

Smoking intensity affects course of bladder cancer

Smoking not only causes bladder cancer—it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that a panel of bladder cancer markers can predict which particular cases are at the highest risk for a fatal outcome.

14 Jan 2013

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

11 Jan 2013

Bladder Cancer Advocacy Network announces availability of three research awards

The Bladder Cancer Advocacy Network (BCAN) has announced the availability of three research awards of $100,000 each, over a two-year period. Applications will be accepted from January 9 to March 6, 2013.

11 Jan 2013

LM11A-31 effective at improving limb movement after spinal cord injury in mice

An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows.

10 Jan 2013

Study reports on development and testing of Hematuria Risk Index to predict cancer risk

Microscopic amounts of blood in urine have been considered a risk factor for urinary tract malignant tumors. However, only a small proportion of patients referred for investigation are subsequently found to have cancer. A new Kaiser Permanente Southern California study published in the February Mayo Clinic Proceedings reports on the development and testing of a Hematuria Risk Index to predict cancer risk.

10 Jan 2013

Kingston University professor receives prestigious prize for work on drug metabolism

The Dean of the Faculty of Science, Engineering and Computing at London's Kingston University has received a prestigious prize recognising her lifetime's work on drug metabolism.

9 Jan 2013

Overall cancer death rates continue to decline in the U.S.: Report

The Annual Report to the Nation on the Status of Cancer, 1975-2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and rectum, female breast, and prostate.

9 Jan 2013

Coffee drinking may also increase incontinence risk for men

Men who suffer from urinary incontinence may benefit from reducing their caffeine intake, suggest findings from a US study.

7 Jan 2013

Viewpoints: McConnell says spending cuts are coming; Plea to Kan. governor to rethink insurance exchange

Predictably, the President is already claiming that his tax hike on the "rich" isn't enough. I have news for him: the moment that he and virtually every elected Democrat in Washington signed off on the terms of the current arrangement, it was the last word on taxes.

4 Jan 2013

PSCA gene’s rs2294008 variant on T nucleotide may increase risk of bladder cancer

Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health.

4 Jan 2013