Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Anti-clotting action of clopidogrel (Plavix) reduced by common heartburn drugs

The anti-clotting action of the medication clopidogrel (Plavix) can be compromised by common drugs for the treatment of heartburn and ulcers resulting in a roughly 50% increase in the combined risk of hospitalization for heart attack, stroke and other serious cardiovascular illnesses, according to a new study presented today at the Society for Cardiovascular Angiography and Interventions (SCAI) 32nd Annual Scientific Sessions.

6 May 2009

Medicare will not pay for genetic tests to determine best Warfarin dosage, according to proposed decision

CMS will not provide Medicare coverage for a genetic test that physicians can use to determine the proper dosage of the blood thinner drug warfarin, the New York Times reports.

5 May 2009

Elevated level of certain protein in urine linked to increased risk for blood clots

Preliminary research suggests that higher than normal levels of the protein albumin in urine is associated with an increased risk for blood clots in the deep veins of the legs or lungs (venous thromboembolism; VTE), according to a study in the May 6 issue of JAMA, the Journal of the American Medical Association.

5 May 2009

Research shows why certain atherosclerotic lesions can turn deadly

A common misconception about arterial plaque is that it inevitably leads to a heart attack or a stroke. New research at Columbia University Medical Center, however, sheds light on why so few plaques in any given individual actually cause a problem. Furthermore, the research has identified a key protein that may promote the conversion from benign to dangerous plaques.

5 May 2009

Drugs designed to tackle endoplasmic reticulum stress might be useful in treating heart disease

Researchers say they have evidence to explain what separates your average blood vessel plaque from those that are at high risk for triggering the development of dangerous - even fatal - blood clots.

5 May 2009

Protein effects of hormone replacement therapy uncovered

An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results.

30 Apr 2009

Researchers identify atrial fibrillation as a stroke predictor in black patients

Predictors of atrial fibrillation (AF or afib) might offer physicians a better way to prevent stroke in blacks, according to a new study done by researchers at Wake Forest University School of Medicine.

29 Apr 2009

Senior men more likely than women to die after pneumonia

Differing biological response to infection between men and women may explain higher death rates among older men who are hospitalized with community-acquired pneumonia (CAP).

29 Apr 2009

Voice response system useful for monitoring anticoagulant patients

Interactive voice response systems may help improve monitoring of patients taking anticoagulants such as warfarin while reducing the workload of clinical staff, found a study by Ottawa researchers in CMAJ.

27 Apr 2009

Lilly granted preliminary injunction to prevent launch of generic Raloxifene

Eli Lilly and Company has announced that the U.S. District Court for the Southern District of Indiana today issued a preliminary injunction to prevent the launch of a generic version of Lilly's medicine Evista (raloxifene HCl tablets) by Teva Pharmaceuticals until the Court renders its final ruling.

22 Apr 2009

Acetylsalicylic acid plus clopidogrel reduces heart attack risk in patients with acute ischaemia

In order to better prevent blood clots, clopidogrel can be prescribed to patients with acute ischaemia of the heart muscle, in addition to acetylsalicylic acid (ASA).

22 Apr 2009

Research may lead to new ways to fight clot formation

When plaques coating blood vessel walls rupture and expose collagen, platelets spring into action to form a blood clot at the damaged site.

16 Apr 2009

New easy to understand guide on treatments for osteoarthritis of the knee

A new pair of plain-language guides from the Agency for Healthcare Research and Quality (AHRQ) examines the effectiveness, safety, and adverse effects of various treatments for osteoarthritis of the knee, including glucosamine and chondroitin, fluid injections, arthroscopic surgery, pain medications and other approaches.

13 Apr 2009

Anti-clotting medications may be associated with brain microbleeds in older adults

Individuals who take aspirin or other medications that prevent blood clotting by inhibiting the accumulation of platelets appear more likely to have tiny, asymptomatic areas of bleeding in the brain, according to a report posted online today that will appear in the June print issue of Archives of Neurology.

13 Apr 2009

Omega-3 fatty acids may help cancer patients undergoing major operations

New research from Trinity College Dublin published in this month's Annals of Surgery points to a potentially significant advance in the treatment of patients undergoing major cancer surgery.

12 Apr 2009

Merck & Co and Cardiome sign agreement for Vernakalant

Merck & Co., Inc. and Cardiome Pharma Corp. has announced a collaboration and license agreement for the development and commercialization of vernakalant, an investigational candidate for the treatment of atrial fibrillation.

9 Apr 2009

Telemonitoring changes the working practice of cardiac nurses

The 9th Annual Spring Meeting of the European Society of Cardiology Council on Cardiovascular Nursing and Allied Professions (CCNAP), organised in cooperation with the Irish Nurses Cardiovascular Association (INCA), is being held at the Royal Dublin Society, Dublin, Ireland, on 24-25 April.

8 Apr 2009

Large safety gaps identified between top and bottom performing hospitals

The 2009 HealthGrades Patient Safety Excellence Award™ recipients were identified in a report issued today by the leading independent healthcare ratings organization.

8 Apr 2009

FDA warns 14 pharmaceutical companies about short internet ads lacking risk information

FDA has warned 14 major pharmaceutical firms about brief Internet advertisements that could have misled patients because they did not include information about health risks related to the drugs, according to letters posted to the agency's Web site Friday, the Wall Street Journal reports.

6 Apr 2009

Moderate kidney disease associated with cardiovascular events

Chronic kidney disease patients face a greater risk of cardiovascular events such as stent thrombosis after being treated for heart attacks, even if their kidney disease is moderate, according to researchers from Wake Forest University Baptist Medical Center.

6 Apr 2009

Blood Clot News and Research

Further Reading

Anti-clotting action of clopidogrel (Plavix) reduced by common heartburn drugs

Medicare will not pay for genetic tests to determine best Warfarin dosage, according to proposed decision

Elevated level of certain protein in urine linked to increased risk for blood clots

Research shows why certain atherosclerotic lesions can turn deadly

Drugs designed to tackle endoplasmic reticulum stress might be useful in treating heart disease

Protein effects of hormone replacement therapy uncovered

Researchers identify atrial fibrillation as a stroke predictor in black patients

Senior men more likely than women to die after pneumonia

Voice response system useful for monitoring anticoagulant patients

Lilly granted preliminary injunction to prevent launch of generic Raloxifene

Acetylsalicylic acid plus clopidogrel reduces heart attack risk in patients with acute ischaemia

Research may lead to new ways to fight clot formation

New easy to understand guide on treatments for osteoarthritis of the knee

Anti-clotting medications may be associated with brain microbleeds in older adults

Omega-3 fatty acids may help cancer patients undergoing major operations

Merck & Co and Cardiome sign agreement for Vernakalant

Telemonitoring changes the working practice of cardiac nurses

Large safety gaps identified between top and bottom performing hospitals

FDA warns 14 pharmaceutical companies about short internet ads lacking risk information

Moderate kidney disease associated with cardiovascular events

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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