Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Clinical experience of biosimilar infliximab in 78 inflammatory bowel disease (IBD) patients presented at Digestive Diseases Week (DDW) 2015 in Washington D.C. showed that the treatment is comparable to the reference medicinal product (RMP) in terms of efficacy and safety.

20 May 2015

Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on cardio-renal, gastrointestinal, and metabolic diseases, today presented Phase 2b clinical trial results that demonstrated statistically significant and clinically meaningful improvement in IBS-C symptoms for tenapanor-treated patients compared to patients receiving placebo.

19 May 2015

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Current users of menopausal hormone therapy (MHT) are more than twice as likely than non-users to develop lower gastrointestinal bleeding and ischemic colitis, especially if they use the therapy for longer durations, according to a study at Digestive Disease Week 2015.

19 May 2015

MDLGI partners with top GI experts to expand most comprehensive gastroenterology test review service

MDLGI provides hospitals; gastroenterologists; surgeons; capsule endoscopy programs; GI clinics; as well as GERD, esophageal and reflux centers around the globe a unique ability allowing consultation with the world’s leading GI experts for detailed analyses of esophageal function testing...

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Patients want to take more active role in decision-making process, study finds

Patients faced with a choice of surgical options want to engage their physicians and take a more active role in decision-making, according to a study (abstract 567) released at Digestive Disease Week 2015.

19 May 2015

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

CDx Diagnostics announced today new clinical data from a multi-center study demonstrating the utility of the WATS3D biopsy for post-ablation surveillance of Barrett’s esophagus and esophageal dysplasia...

18 May 2015

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

18 May 2015

Long-term treatment of GERD: an interview with Chris Rowland, CEO, Medigus

To control reflux symptoms, many people take acid-controlling medications such as Proton Pump Inhibitors, or PPIs. The FDA, however, has issued warnings over the frequent or long-term continued use of PPIs...

18 May 2015

Live, multi-strain probiotic drink may benefit people with ulcerative colitis

People with ulcerative colitis may benefit from taking the live, multi-strain probiotic drink, Symprove, to reduce intestinal inflammation, according to the results of a new study presented today at Digestive Disease Week 2015.

18 May 2015

Investing in new hepatitis C therapies may have significant economic impact

While a new generation of safer, more effective oral medications to treat hepatitis C patients may cost tens of thousands of dollars for a 12-week regiment, investing in these new therapies could generate savings estimated at more than $3.2 billion annually in the U.S. and five European countries, according to a new study (abstract 228) released today at Digestive Disease Week® (DDW) 2015.

18 May 2015

Olympus becomes exclusive distributor of Terumo's GLIDEWIRE Urologic Guidewire in the U.S.

Olympus, a global technology leader in designing and delivering innovative solutions for medical and surgical procedures, among other core businesses, announced today that it has partnered with Terumo Corporation to be the exclusive distributor of the GLIDEWIRE Urologic Hydrophilic Coated Guidewire, a device cleared by the FDA for urological use.

17 May 2015

UEG survey identifies significant variation in current provision of endoscopy services across Europe

Successful implementation of pan-European colorectal cancer (CRC) screening programmes may be pushing endoscopy services to the limit, according to experts from United European Gastroenterology.

15 May 2015

Simple blood test could help predict effectiveness of interferon-based therapy in HCV-infected patients

A simple blood test can be used to predict which chronic hepatitis C patients will respond to interferon-based therapy, according to a report in the May issue of Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association.

13 May 2015

Investigational three-drug combination clears hepatitis C in 93% of patients with liver cirrhosis

A 12-week dose of an investigational three-drug hepatitis C combination cleared the virus in 93 percent of patients with liver cirrhosis who hadn't previously been treated, according to a study in the May 5, 2015, issue of The Journal of the American Medical Association.

7 May 2015

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

The ulcer-causing bacterium Helicobacter pylori can directly interact with stomach stem cells, causing the cells to divide more rapidly, according to a new study by researchers at the Stanford University School of Medicine.

7 May 2015

Exalenz Bioscience investigates clinical utility of BreathID test to diagnose NASH

Exalenz Bioscience, a leader in developing and marketing of non-invasive medical devices for diagnosing and monitoring a range of gastrointestinal and liver diseases, today announced the initiation of a clinical study evaluating the potential of its BreathID test to diagnose nonalcoholic steatohepatitis (NASH).

6 May 2015

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

In patients with chronic hepatitis B virus infection, treatment with tenofovir disoproxil fumarate does not significantly increase the risk of developing renal dysfunction compared with entecavir treatment, a US team reports.

29 Apr 2015

International study finds that two-week diet swap for African-Americans may lower colon cancer risk

African-Americans and Africans who swapped their typical diets for just two weeks similarly exchanged their respective risks of colon cancer as reflected by alterations of their gut bacteria, according to an international study led by researchers at the University of Pittsburgh School of Medicine published online today in Nature Communications.

29 Apr 2015

Special issue of Gastroenterology highlights how food impacts health and disease

Patients are always interested in understanding what they should eat and how it will impact their health. Physicians are just as interested in advancing their understanding of the major health effects of foods and food-related diseases.

28 Apr 2015

Gastroenterology News and Research

Further Reading

New data shows safety and efficacy of biosimilar infliximab treatment in IBD patients

Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

MDLGI partners with top GI experts to expand most comprehensive gastroenterology test review service

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Patients want to take more active role in decision-making process, study finds

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

Long-term treatment of GERD: an interview with Chris Rowland, CEO, Medigus

Live, multi-strain probiotic drink may benefit people with ulcerative colitis

Investing in new hepatitis C therapies may have significant economic impact

Olympus becomes exclusive distributor of Terumo's GLIDEWIRE Urologic Guidewire in the U.S.

UEG survey identifies significant variation in current provision of endoscopy services across Europe

Simple blood test could help predict effectiveness of interferon-based therapy in HCV-infected patients

Investigational three-drug combination clears hepatitis C in 93% of patients with liver cirrhosis

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

Exalenz Bioscience investigates clinical utility of BreathID test to diagnose NASH

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

International study finds that two-week diet swap for African-Americans may lower colon cancer risk

Special issue of Gastroenterology highlights how food impacts health and disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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