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Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Studies have shown that mortality rates in hospitalized patients with COVID-19 are high, ranging between 10% and 30%. REGEN-COV®, a combination of monoclonal antibodies casirivimab and imdevimab, is approved in the United States and other regions for emergency treatment of COVID-19 outpatients with mild to moderate SARS-CoV-2 infection and post-exposure prophylaxis.

10 Nov 2021

Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients

Two open-label randomized controlled trials (RCTs) on the use of inhaled corticosteroids such as budesonide in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients have helped garner attention towards inhaled corticosteroids as a safe and inexpensive treatment method in non-hospitalized SARS-CoV-2 patients.

9 Nov 2021

MRI brain imaging biomarkers bring new levels of precision for prescribing antidepressants

Research led by UT Southwestern has identified MRI brain imaging biomarkers that bring new levels of precision for prescribing the most effective antidepressants.

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

Trial examines differences in gastrointestinal effects of antiplatelet therapy after PCI

Utilizing a magnetically-controlled capsule endoscopy system, the double-blind, randomized OPT-PEACE trial found that nearly all patients receiving antiplatelet therapy developed evidence of abnormal gastrointestinal (GI) mucosal findings on capsule endoscopy.

8 Nov 2021

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

Trial participant Rachel Habiger meets in 2018 with Randall J. Bateman, MD, the director of the Dominantly Inherited Alzheimer Network Trials Unit at Washington University School of Medicine in St. Louis.

8 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Diabetes medication reduces the rate of kidney function decline in CKD patients

Clinical trial data reveal that dapagliflozin - a sodium-glucose cotransporter 2 inhibitor prescribed to treat diabetes - reduces the rate of kidney function decline in patients with chronic kidney disease (CKD). The findings will be presented at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Results of high-impact clinical trials could affect kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

A new study describes the results of the safety and efficacy phase trials of a new COVID-19 vaccine from Cuba.

4 Nov 2021

Novel drug improves management of ulcerative colitis

A new drug improved management of ulcerative colitis, according to a study published in the New England Journal of Medicine.

2 Nov 2021

Zinc supplement may help prevent symptoms of respiratory tract infections, analysis finds

A zinc supplement might help stave off the symptoms of respiratory tract infections, such as coughing, congestion, and sore throat, and cut illness duration, suggests a pooled analysis of the available evidence, published in the open access journal BMJ Open.

2 Nov 2021

What do we really know about vaccine effectiveness?

The politicization of covid vaccines — and, well, just about everything else having to do with the pandemic — has led to confusion, if not utter fatigue.

2 Nov 2021

Stanford neuromodulation therapy causes remission in almost 80% of patients with severe depression

A new type of magnetic brain stimulation brought rapid remission to almost 80% of participants with severe depression in a study conducted at the Stanford University School of Medicine.

30 Oct 2021

Magnus Medical receives FDA's Breakthrough Device Designation for rapid-acting technology to treat major depression

Magnus Medical, Inc., a medical device company, today announced that the U.S. Food & Drug Administration (FDA) has granted the company Breakthrough Device Designation for its individualized, rapid-acting, non-invasive neurostimulation technology designed to treat major depressive disorder (MDD) in people who have not improved sufficiently from antidepressant medication or other treatments.

29 Oct 2021

Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

A team of researchers conducted a randomized, placebo-controlled, adaptive platform trial to evaluate the efficacy of fluvoxamine to prevent COVID-19 progression and hospitalization.

29 Oct 2021

Importance of boosters after priming with J&J Ad26.COV2.S COVID-19 vaccine

A new study compares healthcare workers who underwent homologous Ad26.COV2.S booster vaccination to those who underwent heterologous boosting.

28 Oct 2021

Placebo News and Research

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients

MRI brain imaging biomarkers bring new levels of precision for prescribing antidepressants

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Trial examines differences in gastrointestinal effects of antiplatelet therapy after PCI

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Diabetes medication reduces the rate of kidney function decline in CKD patients

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Results of high-impact clinical trials could affect kidney-related medical care

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

Novel drug improves management of ulcerative colitis

Zinc supplement may help prevent symptoms of respiratory tract infections, analysis finds

What do we really know about vaccine effectiveness?

Stanford neuromodulation therapy causes remission in almost 80% of patients with severe depression

Magnus Medical receives FDA's Breakthrough Device Designation for rapid-acting technology to treat major depression

Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

Importance of boosters after priming with J&J Ad26.COV2.S COVID-19 vaccine

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