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Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Researchers examined the detailed mechanisms of ‘cytokine storm’ that induces ARDS, often resulting in the death of severely ill COVID-19 patients.

21 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

Ensitrelvir, a novel SARS-CoV-2 antiviral

S-217622 reduces the viral load and help alleviate the severity of SARS-CoV-2 in infected hamsters.

17 Feb 2022

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Researchers recently assessed SARS-CoV-2-specific humoral and cellular immune responses induced by the second and third doses of the BNT162b2 COVID-19 messenger ribonucleic acid-based vaccine in the elderly.

17 Feb 2022

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Researchers recently evaluated the efficacy of the Oxford ChAdOx1 (AZD 1222/ AZD2816) vaccine against the Omicron, Delta, and Beta variants of SARS-CoV-2 in Syrian hamsters.

17 Feb 2022

Case ascertainment of myocarditis following COVID-19 booster vaccine

Researchers from the US performed a time case surveillance of myopericarditis following COVID-19 booster vaccination in a cohort of health plan members of Kaiser Permanente Northwest Health System, Portland, Oregano.

17 Feb 2022

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Researchers discuss the genomic and virological characterization of SARS-CoV-2 variants among unvaccinated and vaccinated U.S military personnel.

16 Feb 2022

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Researchers present a simple and efficient plasmonic-magnetic nanorobot for the detection of SARS-CoV-2 RNA.

16 Feb 2022

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Researchers compare the neutralizing antibody titers in individuals who received two or three mRNA vaccine doses and experienced breakthrough infections.

16 Feb 2022

COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Researchers evaluate the role of the placenta in causing stillbirth and neonatal death post-maternal COVID-19 and confirmed placental positivity for SARS-CoV-2.

16 Feb 2022

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

In a recent study posted to the bioRxiv* preprint server, the team of researchers explored the protein-protein interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 1 (Nsp1) and host 40S and 43S ribosomal subunits.

15 Feb 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers identify and investigate the presence and evolution of the SARS-CoV-2 N and S glycoprotein proteins.

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

South African population reveal durable protection by prior infection against pre-Omicron variants

A recent study explored the buildup of immunity developed post-SARS-CoV-2 infection in African people and the impact of SARS-CoV-2 Omicron VOC on the COVID-19 pandemic.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Ribonucleic Acid News and Research

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

N-glycosylation blockers reduce SARS-CoV-2 infection

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

Ensitrelvir, a novel SARS-CoV-2 antiviral

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Case ascertainment of myocarditis following COVID-19 booster vaccine

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Prediction of SARS-CoV-2 epitope candidates for future vaccines

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

South African population reveal durable protection by prior infection against pre-Omicron variants

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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