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Researchers identify an immune cell that helps keep time in the gut

As people go through their daily and nightly routines, their digestive tracts follow a routine, too: digesting food and absorbing nutrients during waking hours, and replenishing worn-out cells during sleep. Shift work and jet lag can knock sleep schedules and digestive rhythms out of whack.

4 Oct 2019

Video images offer real-time view into the kinetics of viral assembly

For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and engineer self-assembling particles.

4 Oct 2019

New link between two important products of nitric oxide discovered

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.

4 Oct 2019

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

The cover for issue 54 of Oncotarget features Figure 2, "Comparative proteomic profiling of the peptides/proteins identified from 293T, IL16lamp2b and mExo-Tat samples," by Lu, et al.

4 Oct 2019

Researchers develop 3D tissue models of brain tumors in a brain-mimicking microenvironment

A team of Tufts University-led researchers has developed three-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response.

4 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

New NIH grant to support innovative skin testing approach for diagnosing Parkinson's disease

Wenquan Zou, MD, PhD, an expert in degenerative neurological diseases, along with his collaborators Shu G. Chen, PhD also from the Case Western Reserve University School of Medicine, Jiyan Ma, MD, PhD, from Van Andel Institute in Grand Rapids, Michigan, and Thomas Beach, MD, PhD, from Banner Sun Health Research Institute, Sun City, Arizona, have received a five-year, $3.6 million grant from the National Institutes of Health for diagnosing Parkinson's disease (PD) via an innovative skin testing approach.

4 Oct 2019

Exploiting the weak spot in pathogenic bacteria to develop new antibiotics

Antibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of "ammunition" because of more and more frequently occurring resistances.

4 Oct 2019

The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

A new study has revealed how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that can be transmitted through the generations.

4 Oct 2019

Phage engineering gives antibacterial therapy a new lease of life

Researchers have been identifying and modifying known phages to fight against infectious bacteria.

4 Oct 2019

Rapid Novor moves into a new state-of-the-art facility for next phase of growth

Rapid Novor, Inc., the world's leader in antibody protein sequencing using mass spectrometry, is pleased to announce that it has moved into a new, 5000 sqft, purpose-built, state-of-the-art facility.

From Rapid Novor Inc 4 Oct 2019

New study pinpoints emergence and progression of Alzheimer's plaque in the brain

Long before symptoms like memory loss even emerge, the underlying pathology of Alzheimer's disease, such as an accumulation of amyloid protein plaques, is well underway in the brain.

4 Oct 2019

Rare genetic disorder more common than previously thought, report shows

Approximately one in forty-two thousand children are born with a disease called CDKL5 Deficiency Disorder, according to a new medical report recently published in the journal Brain and presented last month at the 13th European Pediatric Neurology Society Congress in Athens, Greece.

4 Oct 2019

Protein C News and Research

Researchers identify an immune cell that helps keep time in the gut

Video images offer real-time view into the kinetics of viral assembly

New link between two important products of nitric oxide discovered

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

Researchers develop 3D tissue models of brain tumors in a brain-mimicking microenvironment

GW researchers show connection between bacteria in the microbiome and colon cancer

New defensive mechanism against bacterial wound infections discovered

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

New NIH grant to support innovative skin testing approach for diagnosing Parkinson's disease

Exploiting the weak spot in pathogenic bacteria to develop new antibiotics

The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

Phage engineering gives antibacterial therapy a new lease of life

Rapid Novor moves into a new state-of-the-art facility for next phase of growth

New study pinpoints emergence and progression of Alzheimer's plaque in the brain

Rare genetic disorder more common than previously thought, report shows

Targeting two genetic faults in cancer cells could hold the key to treating leukemia

GlobalData: Alternative livestock feed to aid in the production of sustainable meat

Researchers are developing new therapy to counter the effects of traumatic brain injury

Study may help in personalizing treatment for lung cancer, develop new drugs

Study explores how macrophage specialization gets disrupted by liver disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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