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New study maps cellular fingerprints driving childhood arthritis

A new groundbreaking study by researchers from University of Birmingham, UCL, Great Ormond Street Hospital and Birmingham Children's Hospital has revealed important clues into what is driving disease in children with arthritis.

2 Jul 2025

New protein target offers hope for chronic inflammation treatment

Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years.

2 Jul 2025

TET2 mutations in blood stem cells linked to lower Alzheimer's risk

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease.

2 Jul 2025

Breakthrough AI uncovers promising Rett syndrome treatment

Rett syndrome is a devastating rare genetic childhood disorder primarily affecting girls. Merely 1 out of 10,000 girls are born with it and much fewer boys.

2 Jul 2025

Scientists reveal how chemotherapy causes genetic damage in healthy blood

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.

2 Jul 2025

Cornell scientists use natural cell proteins to track molecular behavior

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors.

2 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Mature dendritic cell vesicles enhance influenza vaccine effectiveness

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body's immune response, according to a study by researchers in the Institute for Biomedical Sciences at Georgia State University.

2 Jul 2025

Leukemia-on-a-chip offers breakthrough in personalized cancer treatment

A team of researchers led by NYU Tandon School of Engineering's Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.

2 Jul 2025

New strategy enhances immunotherapy effectiveness against glioblastoma by utilizing gut microbes

Advanced treatments, known as immunotherapies that activate T cells—our body's immune cells—to eliminate cancer cells, have shown limited efficacy as standalone therapies for glioblastoma, the most lethal form of brain tumor.

2 Jul 2025

Fidelio Capital partners with Alphalyse to accelerate the global roll-out of LC-MS host cell protein analytics

Alphalyse, a fast-growing Danish specialist contract research organization (CRO) that has developed GMP‑validated liquid‑chromatography mass‑spectrometry (LC‑MS) assays for host‑cell‑protein (HCP) impurity testing in biologic drugs, today announces that Fidelio Capital has acquired a majority stake in the company.

From Alphalyse A/S 2 Jul 2025

Drug combination shows promise for treating aggressive T-cell lymphomas

Relapsed/refractory peripheral and cutaneous T-cell lymphomas (R/R PTCL and CTCL) are aggressive blood cancers that often resist standard therapy. Patients with these lymphomas may require stem cell transplants, but the disease needs to be brought under control before patients can undergo this treatment.

2 Jul 2025

Experimental medication sensitizes glioblastoma to treatment and blocks tumor spread

A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain cancer newly sensitive to both radiation and chemotherapy drugs, and blocks the cancer's ability to invade other tissue, a new study shows.

2 Jul 2025

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2 Jul 2025

Study enhances the understanding of urolithiasis pathogenesis

A recent study published in Genes & Diseases reveals new insights into the relationship between immune cell characteristics, blood metabolites, and the risk of urolithiasis.

2 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Timepoint at which B cells transform into leukemic cells impacts treatment outcomes

New findings show that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment outcomes for pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL).

2 Jul 2025

Uncovering the link between viruses and neurodegeneration through primate models

In a comprehensive Genomic Press Innovators & Ideas interview, Dr. Danielle Beckman reveals how her passion for microscopy has evolved into a mission to understand viral impacts on brain health, offering hope for patients suffering from post-viral neurological symptoms.

2 Jul 2025

Could your pregnancy diet shape your child’s immune future?

Researchers found that a pro-inflammatory maternal diet during pregnancy was linked to a 16% increased risk of type 1 diabetes in offspring. This large Danish cohort study suggests that maternal dietary patterns may shape long-term autoimmune risk in children.

2 Jul 2025

Researchers find gut bacteria rapidly soak up ‘forever chemicals’

Scientists have demonstrated that select human gut bacteria can bioaccumulate and sequester PFAS ‘forever chemicals’, increasing faecal excretion in humanized mice. The findings reveal a potential microbiome-based strategy to reduce PFAS body burden, though clinical benefit in humans remains unproven.

1 Jul 2025