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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester.

23 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

In new evidence-based guidelines, the American Gastroenterological Association recommends non-invasive biomarkers as a first-line strategy for monitoring many patients with ulcerative colitis (UC).

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Study examines link between different epigenetic age measures and lung cancer risk

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, "Epigenetic age and lung cancer risk in the CLUE II prospective cohort study."

17 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

Patients with resectable non-small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes.

15 Feb 2023

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

Integrating AI with infrared imaging to improve colon cancer diagnosis

Artificial intelligence and infrared imaging automatically classify tumors and are faster than previous methods.

14 Feb 2023

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

Ipsen (Euronext: IPN; ADR: IPSEY) today announced three-year minimum, 44-month median, follow-up results from the Phase III CheckMate -9ER trial showing that Cabometyx® (cabozantinib) in combination with nivolumab provides survival and response rate benefits after three-years in the first-line treatment of advanced renal cell carcinoma (aRCC), compared to sunitinib.

From Ipsen 14 Feb 2023

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

A study reveals a previously unknown way in which cannabidiol (CBD), a substance found in cannabis, reduces seizures in many treatment-resistant forms of pediatric epilepsy.

13 Feb 2023

Study provides insight into the neural mechanisms of motor skill learning

A new study led by Cedars-Sinai investigators identified a marker in the brain that controls the ability to reach and grasp, a fundamental fine motor skill that is often impaired in motor or neural injuries such as a stroke.

13 Feb 2023

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Declines in prostate-specific antigen (PSA) level after treatment with the next-generation androgen receptor inhibitor drug enzalutamide predict improved survival rates in men with non-metastatic castration-resistant prostate cancer (nmCRPC), reports The Journal of Urology, an Official Journal of the American Urological Association.

10 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

Biomarker News and Research

Further Reading

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

First molecular biomarker for acquired generalized lipodystrophy discovered

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Study examines link between different epigenetic age measures and lung cancer risk

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

Integrating AI with infrared imaging to improve colon cancer diagnosis

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

Study provides insight into the neural mechanisms of motor skill learning

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Study examines long-term relationship between brain health, concussion history and sports

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

New method for detecting cancers could help provide clearer disease prognoses

Toddlers' level of attention to motherese may be a diagnostic marker of ASD

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