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Inventor of hepatitis C cure wins prestigious award from University of Edinburgh

A medicinal chemist who found a cure for the viral disease hepatitis C has received a prestigious award from the University of Edinburgh.

3 May 2020

Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

When kidney transplants first came into practice in the 1950s, patients with chronic kidney disease could finally picture freedom from the unrelenting routine of blood-cleansing dialysis treatments. Just over a half-century later, demand has completely outstripped supply.

2 May 2020

FMT improves clinical outcomes in extremely ill patients with drug-resistant bacteria

Transferring fecal matter from the digestive systems of healthy donors to extremely ill patients who had previously been infected with drug-resistant bacteria resulted in shorter hospital stays, fewer bloodstream infections and infections that were easier to treat, according to research that was selected for presentation at Digestive Disease Week 2020.

30 Apr 2020

Study explores the growth rate effect of gut bacteria on break down of dietary fibers

It is known that approximately 80% of human immune system functions in the gastrointestinal tract. Gut bacteria and their metabolites play a fundamental role in the interaction between gut and other organs.

29 Apr 2020

Immune-regulating drug reverses dental problems in aging mice

A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study published today in eLife.

28 Apr 2020

Many cells in human uterus carry 'cancer-driving' mutations that arise early in life

Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists from the Wellcome Sanger Institute, the University of Cambridge and their collaborators.

23 Apr 2020

Meis1 protein plays key role in stopping cell division in the heart

UT Southwestern Medical Center scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart, they report today in Nature.

23 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Should age be a prioritizing factor in deciding who gets treated for COVID-19?

With pubic healthcare systems becoming increasingly strained due to the impact of COVID-19, healthcare professionals are having to question whether to factor age in as a priority when deciding who to treat.

22 Apr 2020

Immunity to coronavirus infection may help stem the pandemic

The raging coronavirus pandemic is causing immense fear and uncertainty across the world. One of the most distressing aspects of COVID-19 disease is the seemingly large number of unknowns. These include the burning question of immunity. Does a person who was sick with the COVID-19 and then recovered or was infected without symptoms, have immunity against re-infection?

21 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

Landmark 30-year study describes clinical course of patients with Crigler-Najjar syndrome

A new study summarizes more than 30 years of clinical experience and describes the clinical course of 28 individuals homozygous for damaging mutations in the UGT1A1 gene who were born between 1984 and 2015 with Crigler-Najjar syndrome.

17 Apr 2020

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests.

13 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

UChicago Medicine launches clinical trial to explore plasma transfusions for COVID-19 patients

The University of Chicago Medicine is launching a clinical trial to study whether blood plasma from people who have recovered from COVID-19 can be used to treat patients who are still in the hospital with severe disease symptoms.

13 Apr 2020

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

After a lightening round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells to block the life-threatening lung inflammation that accompanies severe cases of COVID-19.

11 Apr 2020

ERA-EDTA creates European database of dialysis, transplanted patients with COVID-19

The ERA-EDTA has created a European database that collects granular individual data of dialysis patients and transplanted patients with COVID-19.

9 Apr 2020

Using computer software to optimize treatment for diabetic kidney diseases

Diabetic kidney diseases are the main cause of kidney failure in industrialized countries. An international, EU-funded R&D project - which is being headed by the Medical University of Innsbruck, and involves collaboration with the Medical University of Vienna and international partners - is being implemented with the aim of using computer software to provide personalized predictions of the disease's progression and bring about improvements in individuals' responses to treatment.

9 Apr 2020

Researchers succeed in restoring mobility and sensation of touch in stroke-afflicted rats

Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains.

8 Apr 2020

USC scientists report wider benefits of well-known hangover drug

A well-known hangover drug not only helps soothe pounding headaches but also triggers profound changes that protect the liver, USC scientists report in new findings that could help prevent alcohol-related harm.

7 Apr 2020

Transplant News and Research

Inventor of hepatitis C cure wins prestigious award from University of Edinburgh

Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

FMT improves clinical outcomes in extremely ill patients with drug-resistant bacteria

Study explores the growth rate effect of gut bacteria on break down of dietary fibers

Immune-regulating drug reverses dental problems in aging mice

Many cells in human uterus carry 'cancer-driving' mutations that arise early in life

Meis1 protein plays key role in stopping cell division in the heart

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Should age be a prioritizing factor in deciding who gets treated for COVID-19?

Immunity to coronavirus infection may help stem the pandemic

New study may offer a breakthrough in treating telomere diseases

Landmark 30-year study describes clinical course of patients with Crigler-Najjar syndrome

Tumors commandeer cell death pathway to avoid immune system attack after radiation

CRISPR may help in kidney-transplants by detecting viruses

UChicago Medicine launches clinical trial to explore plasma transfusions for COVID-19 patients

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

ERA-EDTA creates European database of dialysis, transplanted patients with COVID-19

Using computer software to optimize treatment for diabetic kidney diseases

Researchers succeed in restoring mobility and sensation of touch in stroke-afflicted rats

USC scientists report wider benefits of well-known hangover drug

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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