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New AI approach can teach itself to design new drug molecules from scratch

An artificial-intelligence approach created at the University of North Carolina at Chapel Hill Eshelman School of Pharmacy can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates.

1 Aug 2018

Researchers engineer three cell lines to produce nonproprietary versions of NISTmAb

When the National Institute of Standards and Technology issued the world's first standardized monoclonal antibody in July 2016, the exhaustively analyzed protein known as NISTmAb was intended as a valuable tool for biopharmaceutical companies.

1 Aug 2018

Acetyl-L-carnitine chemical in blood connected to depression

A group of researchers from Stanford in collaboration with other universities have found that in humans a low level of acetyl-L-carnitine or L-acetyle carnitine in blood could be a predictor of the duration and severity of depression.

1 Aug 2018

Mortality rate increases during tropical nights in Barcelona

A statistical analysis of the effects of very hot nights on the death rate in Barcelona's environment reveals that, during these nocturnal periods, more deaths occur due to natural, respiratory and cardiovascular causes.

31 Jul 2018

Alzheimer’s-in-a-dish model made better with microfluidic system

Researchers from Massachusetts have used a microfluidic device to incorporate neuroinflammation into the Alzheimer's-in-a-dish model for drug discovery.

31 Jul 2018

New research into how cells communicate could pave way for improved cancer treatments

Pioneering new research into the way in which cells communicate with each other could hold the key to unlocking new, improved treatment for life-threatening diseases, including cancer.

31 Jul 2018

New study may lead to improved treatment for type 2 diabetes

Improved treatment for type 2 diabetes might result from a new study by University of Queensland researchers.

31 Jul 2018

Researchers describe strategy used by Oropouche virus to replicate in human cells

The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo in Brazil and international collaborators in an article published in the journal PLOS Pathogens.

31 Jul 2018

New method to evaluate drug benefits may reduce health care costs

With the cost of drugs a critical issue in health care, health insurance companies and government payers need to understand how new and existing drugs compare in terms of benefits and risks.

31 Jul 2018

Research may help advance search for more effective drugs to treat Alzheimer's disease

Two new studies published by investigators from Brigham and Women's Hospital illustrate that not all forms of amyloid-beta protein - the protein thought to initiate Alzheimer's disease - play an equally menacing role in the progress of the disease.

31 Jul 2018

FDA approves first therapy for patients with rare tumors of the adrenal gland

The U.S. Food and Drug Administration today approved Azedra (iobenguane I 131) injection for intravenous use for the treatment of adults and adolescents age 12 and older with rare tumors of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumor site and require systemic anticancer therapy.

31 Jul 2018

“Vaginal rejuvenation” procedures and devices unsafe says FDA

According to a warning from the United States Food and Drugs Administration (FDA), devices that are being sold for “vaginal rejuvenation” in women who are suffering from urinary incontinence or menopausal and sexual symptoms, can cause serious harm.

31 Jul 2018

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

Clinical trials at University of Colorado Cancer Center and elsewhere now result in the drug ivosidenib earning approval from the U.S. Food and Drug Administration for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with a susceptible isocitrate dehydrogenase-1 mutation.

30 Jul 2018

UCI receives $9 million grant to find long-term impact of cannabis exposure on adolescent brain

The National Institute on Drug Abuse, part of the National Institutes of Health, has awarded the University of California, Irvine School of Medicine, a 4-year, $9 million grant aimed at determining the long-term impact of cannabis exposure on the adolescent brain.

30 Jul 2018

New improved mouse model could revolutionize bone metastasis research

Researchers at Tokyo Institute of Technology propose an improved mouse model that could revolutionize bone metastasis research. Their method, which involves injecting cancer cells via the so-called caudal artery in the mouse tail, overcomes many limitations of traditional mouse models.

30 Jul 2018

Researchers investigate new treatment that is effective against recurrent breast cancers

What do one in five breast cancers have in common? Large amounts of a protein called HER2 (or human epidermal growth factor receptor 2).

30 Jul 2018

BRAF inhibitors may be effective at treating rare ovarian cancer, study shows

New research has shown that ovarian cancer patients with a tumor mutation in the BRAF gene respond exceptionally well to treatment with targeted drugs, known as BRAF inhibitors.

30 Jul 2018

Researchers discover various mechanisms of resistance to cancer therapy

An international research team under the co-direction of the University of Bern and the Netherlands Cancer Institute has discovered various mechanisms of resistance to cancer therapy. The findings help researchers to understand the self-repair of cancer cells after a therapy and thus help to fight resistant tumours more efficiently.

30 Jul 2018

$Researchers use magnetic surgical cement for spinal fractures and targeted drug delivery$

Researchers use magnetic surgical cement for spinal fractures and targeted drug delivery

Patients with spinal fractures caused by tumors or osteoporosis usually undergo a procedure called kyphoplasty, where the fracture is filled with surgical cement.

28 Jul 2018

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair.

28 Jul 2018

Drugs News and Research

New AI approach can teach itself to design new drug molecules from scratch

Researchers engineer three cell lines to produce nonproprietary versions of NISTmAb

Acetyl-L-carnitine chemical in blood connected to depression

Mortality rate increases during tropical nights in Barcelona

Alzheimer’s-in-a-dish model made better with microfluidic system

New research into how cells communicate could pave way for improved cancer treatments

New study may lead to improved treatment for type 2 diabetes

Researchers describe strategy used by Oropouche virus to replicate in human cells

New method to evaluate drug benefits may reduce health care costs

Research may help advance search for more effective drugs to treat Alzheimer's disease

FDA approves first therapy for patients with rare tumors of the adrenal gland

“Vaginal rejuvenation” procedures and devices unsafe says FDA

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

UCI receives $9 million grant to find long-term impact of cannabis exposure on adolescent brain

New improved mouse model could revolutionize bone metastasis research

Researchers investigate new treatment that is effective against recurrent breast cancers

BRAF inhibitors may be effective at treating rare ovarian cancer, study shows

Researchers discover various mechanisms of resistance to cancer therapy

Researchers use magnetic surgical cement for spinal fractures and targeted drug delivery

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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