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IUPUI researchers examine pain experience, pain management among Hispanic Americans

Hispanic Americans report fewer pain conditions compared with non-Hispanic white or black Americans, according to a critical review and analysis of more than 100 studies on pain experience and pain management among Hispanic Americans.

15 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

Aralez resubmits NDA package for YOSPRALA to FDA

Aralez Pharmaceuticals Inc., a global specialty pharmaceutical company, today announced that it has resubmitted to the U.S. Food and Drug Administration the New Drug Application ("NDA") for its investigational candidate, YOSPRALA (PA32540/PA8140) for the secondary prevention of cardiovascular disease in patients at risk for aspirin-induced gastric ulcers.

15 Mar 2016

Ibrutinib and idelalisib drugs for chronic lymphatic leukaemia can prolong survival time of high-risk patients

Studies conducted at the Comprehensive Cancer Center at MedUni Vienna and Vienna General Hospital show that the drugs ibrutinib and idelalisib used in the targeted treatment of chronic lymphatic leukaemia can significantly prolong the survival time of high-risk patients.

15 Mar 2016

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

Many Chamorro villagers on the island of Guam perished from a puzzling paralytic disease that combines aspects of ALS, Alzheimer's, and Parkinson's disease.

From Huron Technologies 14 Mar 2016

Neurofeedback decreases pain, increases quality of life in patients with neuropathic pain

A new study from The University of Texas MD Anderson Cancer Center evaluating the use of neurofeedback found a decrease in the experience of chronic pain and increase quality of life in patients with neuropathic pain.

14 Mar 2016

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous.

14 Mar 2016

Beta-blockers could have potential benefit for COPD patients

Beta-blockers could be used to reduce the risk of chronic obstructive pulmonary disease (COPD) exacerbations, according to new findings.

13 Mar 2016

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss.

11 Mar 2016

Periodontitis linked to greater rates of cognitive decline in Alzheimer's disease patients

A new study, jointly led by the University of Southampton and King's College London, has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer's Disease.

11 Mar 2016

Findings offer novel way for creating drugs to stop mitochondria from destroying cells during stress

Malfunctioning mitochondria — the power plants in cells — are behind the damage caused by strokes, heart attacks, and neurodegenerative diseases, but little has been known about how to stop these reactors from melting down, destroying cells and tissue. Mitochondria also take up calcium, which regulates energy production.

11 Mar 2016

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55. 80 percent of these patients will die due to metastasis within five years after the cancer has been first detected.

11 Mar 2016

STING agonists developed to induce cellular death in B cell malignancies

In almost every mammalian cell, you will find the endoplasmic reticulum, a network of continuous membranes responsible for controlling metabolism as well as the folding, assembly and secretion of proteins.

11 Mar 2016

Excess comorbidity flagged in MS patients

Patients with multiple sclerosis have more comorbidities than would be expected for their age, even at the time of diagnosis, say researchers.

10 Mar 2016

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.

10 Mar 2016

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

On World Kidney Day, leading experts from the European ADPKD Forum today issue a collaborative letter to over 350 European decision makers (European Parliament, European Commission, Council representatives) celebrating the year one progress of the Brussels Declaration on ADPKD, while calling for urgent backing from policy makers to reduce the widespread inequalities and variations in care that remain.

10 Mar 2016

World Kidney Day 2016 focuses on children

On Thursday March 10th we are celebrating the 11th edition of World Kidney Day (WKD), a joint initiative organized by the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF).

10 Mar 2016

VolitionRx's NuQ blood test accurately detects 86% of subjects with Idiopathic Pulmonary Fibrosis

VolitionRx Limited today announced preliminary data from a pilot study demonstrating that the Company’s NuQ® blood test detected 86% of subjects with a deadly lung disease, called Idiopathic Pulmonary Fibrosis (IPF).

10 Mar 2016

Pioneering progress on ADPKD: an interview with Tess Harris

ADPKD is a chronic, progressive and inherited kidney disease characterized by fluid-filled cysts that develop in the kidneys and other organs. It is the most common inherited kidney disease, and affects millions worldwide.

10 Mar 2016

IUPUI researcher awarded $1.1 million grant to develop tools to improve care for chronic pain patients

An Indiana University-Purdue University Indianapolis researcher has been awarded $1.1 million to develop information-based tools to help primary care providers improve care for patients with chronic pain, a condition that affects 100 million Americans at a cost of $630 billion annually in health care costs and lost worker productivity.

10 Mar 2016

Chronic News and Research

IUPUI researchers examine pain experience, pain management among Hispanic Americans

Study could lead to potential new therapeutic target with fewer side effects for hypertension

Aralez resubmits NDA package for YOSPRALA to FDA

Ibrutinib and idelalisib drugs for chronic lymphatic leukaemia can prolong survival time of high-risk patients

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

Neurofeedback decreases pain, increases quality of life in patients with neuropathic pain

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Beta-blockers could have potential benefit for COPD patients

Low bone mass higher in HIV-infected males than in females

Periodontitis linked to greater rates of cognitive decline in Alzheimer's disease patients

Findings offer novel way for creating drugs to stop mitochondria from destroying cells during stress

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

STING agonists developed to induce cellular death in B cell malignancies

Excess comorbidity flagged in MS patients

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

World Kidney Day 2016 focuses on children

VolitionRx's NuQ blood test accurately detects 86% of subjects with Idiopathic Pulmonary Fibrosis

Pioneering progress on ADPKD: an interview with Tess Harris

IUPUI researcher awarded $1.1 million grant to develop tools to improve care for chronic pain patients

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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