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Cutting-edge laboratory technique recapitulates brain development more accurately than ever

A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever, according to a new study from Case Western Reserve University School of Medicine.

26 Jul 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

Scientists uncover new strategy to kill tumors without harming healthy cells

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects.

26 Jul 2018

Ciprofloxacin may disrupt normal functions of connective tissue

The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment

26 Jul 2018

Researchers develop artificial enzymes that drive reactions on living cells

Nature has evolved thousands of enzymes to facilitate the many chemical reactions that take place inside organisms to sustain life.

26 Jul 2018

New combination approach may help crush resistance to treatment in lung cancer patients

New-generation lung cancer drugs have been effective in a large number of patients, but within about a year, the patients tend to develop resistance to the therapy.

26 Jul 2018

Researchers find compounds that may pave way for new drugs against diabetes, obesity

A new study reveals that several drugs for treating hematological cancers are less effective than expected in inhibiting a special enzyme.

26 Jul 2018

Study gives insights into how better clinical trials can address ‘critically low’ dementia research

New research gives insights into how the design of clinical trials can improve to address the "critically low" research pipeline and improve the chances of finding effective dementia therapies.

26 Jul 2018

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Long-lasting control of HIV infection without antiretroviral therapy is a feasible goal that deserves vigorous pursuit, Anthony S. Fauci, M.D., will assert during a lecture on Wednesday, July 25 at the 22nd International AIDS Conference in Amsterdam.

26 Jul 2018

Research provides new roadmap for repairing damaged brain cells in multiple sclerosis

Research published today in the journal Nature provides new understanding about how drugs can repair damaged brain cells that cause disability in patients with multiple sclerosis.

26 Jul 2018

Aggressive lowering of blood pressure reduces MCI risk, study shows

Significant reductions in the risk of mild cognitive impairment (MCI), and the combination of MCI and dementia, have been shown for the first time through aggressive lowering of systolic blood pressure in new research results from the federally-funded SPRINT MIND Study reported at the Alzheimer's Association International Conference 2018 in Chicago.

25 Jul 2018

Clinical trials for heart disease under-represent women and older people

Trying to determine how best to treat a patient, doctors often look to randomized clinical trials to guide their choice of what drug to prescribe.

25 Jul 2018

Déjà voodoo: Pharma’s promises to curb drug prices have been heard before

Prescription drug prices were soaring. Angry policymakers swore they'd take action. Pharma giant Merck responded by promising to address the problem voluntarily, vowing to keep price increases under the overall rate of inflation.

25 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

New opioid prescription control framework is a 'funhouse mirror image' of prior monopoly

A rise in addiction and overdose deaths involving opioids in the United States has spurred a series of initiatives focused on reducing opioid risks, including several related to prescription of opioids in care of pain.

25 Jul 2018

Physician discusses role of telehealth in disaster response

Telehealth, the use of TV and computer monitors to deliver healthcare remotely, is proving to be a valuable addition to many practices.

25 Jul 2018

Study: Blood test can predict response of advanced prostate cancer patients to treatments

An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.

25 Jul 2018

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication.

25 Jul 2018

Updated recommendations for HIV prevention and treatment in adults

The International Antiviral Society-USA Panel has released updated recommendations for the treatment and prevention of HIV infection in adults, published in the Journal of the American Medical Association. Michael Saag, M.D., director of the University of Alabama at Birmingham's Center for AIDS Research, served as the article's lead author.

24 Jul 2018

New research uncovers AEP enzyme's importance to immunity

The importance of the enzyme AEP as a key regulatory of the immune system has been discovered in new research from Newcastle University, UK.

24 Jul 2018

Drugs News and Research

Cutting-edge laboratory technique recapitulates brain development more accurately than ever

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Scientists uncover new strategy to kill tumors without harming healthy cells

Ciprofloxacin may disrupt normal functions of connective tissue

Researchers develop artificial enzymes that drive reactions on living cells

New combination approach may help crush resistance to treatment in lung cancer patients

Researchers find compounds that may pave way for new drugs against diabetes, obesity

Study gives insights into how better clinical trials can address ‘critically low’ dementia research

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Research provides new roadmap for repairing damaged brain cells in multiple sclerosis

Aggressive lowering of blood pressure reduces MCI risk, study shows

Clinical trials for heart disease under-represent women and older people

Déjà voodoo: Pharma’s promises to curb drug prices have been heard before

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

New opioid prescription control framework is a 'funhouse mirror image' of prior monopoly

Physician discusses role of telehealth in disaster response

Study: Blood test can predict response of advanced prostate cancer patients to treatments

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

Updated recommendations for HIV prevention and treatment in adults

New research uncovers AEP enzyme's importance to immunity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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