Protein C News and Research

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Temporal fluctuations in protein concentrations can determine fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount of certain proteins play a direct and significant role on biological processes.

26 Sep 2019

'A new era of drug discovery’: Company develops drug using AI

For the first time, a company has discovered a drug target and corresponding candidate using artificial intelligence (AI).

26 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

Investigational drug may offer new treatment option for patients with lung and kidney cancer

Pegilodecakin, a first-in-class drug currently in clinical trials, has shown positive safety results and may offer a potential new treatment avenue for patients with non-small cell lung cancer (NSCLC) and kidney cancer.

26 Sep 2019

Experimental treatment shows early promise to help nearly half of DMD patients

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy.

25 Sep 2019

Mystery underlying cardiac toxicity caused by diabetes drugs solved

Like catching two fish with one worm, treating two problems with a single drug is efficient, but exceedingly difficult.

25 Sep 2019

New needle-free 'exosome' treatment to reduce wrinkles in UV-exposed mice

In the quest for a more youthful appearance, many people slather ointments on their skin or undergo injections of dermal fillers. But topical treatments often aren't very effective because they don't penetrate deep within the skin, whereas the results from injections typically last for only a few months and can be painful.

25 Sep 2019

Dormant HIV reservoirs could be killed with RNA switch

Researchers from the University of California San Diego School of Medicine have found cellular triggers within the immune cells that could be controlled in order to kill dormant HIV-1 reservoirs in individuals with HIV-1.

25 Sep 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Johns Hopkins researchers link a gene to melanoma growth and spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3.

From Johns Hopkins Medicine 25 Sep 2019

Americans still eat too many low-quality carbs and saturated fats, say experts

A report card has shown that adults are typically still eating too many low-quality carbohydrates and saturated fats.

25 Sep 2019

Study on gene mutations may lead to better diagnosis and treatment for cancer

When a cell divides into two daughter cells, it must replicate its DNA according to a very specific scenario. In the presence of some disruptive elements, however, cancer cells are unable to perform this operation optimally; replication then takes place more slowly and less efficiently.

25 Sep 2019

Urine test for detection of early-stage pancreatic cancer reaches final stage of validation

A urine test that can detect early stage pancreatic cancer has reached the final stage of validation before being developed for use with patients.

25 Sep 2019

TUM researchers reveal how chaperones detect immature immune signaling proteins

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules.

24 Sep 2019

7-year-old treated with FDA-approved gene therapy for Leber congenital amaurosis

When Zion Grant was 3 months old his mother Daisy Dodd noticed he wasn't tracking her with his eyes. Zion would fixate on a light in the room, but not on her face.

24 Sep 2019

'Report card' on American diet: Adults consuming more low-quality carbs and fat than recommended

Despite years of steady advice and guidance on healthy eating, a 'report card' on the American diet shows adults are still consuming too many low-quality carbohydrates and more saturated fat than recommended, according to researchers at the Friedman School of Nutrition Science and Policy at Tufts University and the Harvard T.H. Chan School of Public Health.

24 Sep 2019