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Nanoscale syringe-like bacterial structures could be used to deliver novel drugs

By scraping tubeworms off the bottom of boats in the San Diego harbor to study them, San Diego State University researchers discovered that a beneficial bacterium that aids them in establishing colonies could also be a boon for human health, because the same process might already take place in the human gut.

17 Sep 2019

Pros and cons of gene editing technology

CRISPR technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in the journal "Trends in Cell Biology" from 12 September 2019.

17 Sep 2019

Scientists pinpoint cause of fatal genetic disorder in children

Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3.

17 Sep 2019

Using everyday materials as tissue scaffolds

As the global demand for tissue and organ transplants significantly outstrips supply, tissue engineering might provide a potential solution. But one of the significant challenges in tissue engineering is growing tissue in 3D, and the scaffolds used to position cells to develop tissue-specific functions are often challenging or prohibitively expensive to develop.

17 Sep 2019

Mutant live attenuated Ebola virus elicits protective immunity in monkeys

Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show September 17 in the journal Cell Reports.

17 Sep 2019

World Alzheimer’s Day 2019: A timely reminder of urgent need for new drugs to tackle disease

As World Alzheimer’s Day 2019 approaches (21 September), with the aim this year of raising global awareness and understanding of the stigma, stereotypes and myths that surround a dementia diagnosis;

17 Sep 2019

Researchers identify potential target for diabetes-associated Alzheimer's disease

Researchers have identified a protein that may contribute to the progression of Alzheimer’s disease pathology in type-2 diabetes, reports a new study of male mice and human brain tissue. The research could have implications for future drug development.

From Society for Neuroscience 17 Sep 2019

Bone marrow-derived cells also travel to the womb to help pregnancy

Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to research published September 12 in the open-access journal PLOS Biology.

From PLOS ONE 17 Sep 2019

Strongest genetic risk factor for Alzheimer’s disease impairs function of human microglia

A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer’s disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. These findings pave the way for new, effective treatment approaches for AD. The results were published in Stem Cell Reports.

17 Sep 2019

ACA and chiropractors encourage people to take steps for better musculoskeletal health

The American Chiropractic Association and chiropractors nationwide are encouraging the public to take steps to better musculoskeletal health during National Chiropractic Health Month this October.

17 Sep 2019

Chemist explores link between Alzheimer's and copper protein molecules in brain cells

A University of Houston chemist is exploring the link between copper protein molecules in brain cells and neurodegenerative diseases like Alzheimer's.

17 Sep 2019

Mutated ciliary genes tied to heart valve birth defect

The heart pumps blood throughout the body to provide the needed oxygen and nutrients. In the heart, blood flows to get oxygen from the lungs to deliver to the cells. Some of the most important structures in the heart are the valves, because they prevent the backflow of blood, avoiding the mixture of oxygenated blood with the ones that still need to be oxygenated.

17 Sep 2019

New method developed to address failures in promising anti-cancer drug

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies.

17 Sep 2019

Stopping cold viruses dead by blocking replication

The common cold virus (and its more deadly cousins, the viruses that cause polio and acute flaccid myelitis) may just have met its nemesis. In a recent study published in the journal Nature Microbiology on September 16, 2019, scientists reported a potentially successful new approach to stop cold viruses from replicating inside human cells – by blocking the formation of a protein that is vital to this process.

17 Sep 2019

No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

Gut bacterial changes influence lupus treatment results in pregnancy

The course of pregnancy, like that of true love, doesn’t always run smooth when you have lupus, correctly called systemic lupus erythematosus (SLE). This autoimmune disease is an occasionally violent, occasionally subdued, chronic inflammation that constantly smolders within multiple tissues in the body.

16 Sep 2019