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Promising gene editing therapy shows hope in sickle cell disease cure

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

14 Jun 2024

Short-term alcohol abstinence worsens gut health in alcohol use disorder patients

A study published in PLoS ONE found that short-term abstinence from alcohol in AUD patients exacerbates gut dysbiosis and increases mental distress, contrary to expected improvements.

14 Jun 2024

Younger gut microbiota age reduces cardiovascular disease risk in older adults

Researchers identified gut microbiota signatures and developed a microbial age metric, demonstrating that a younger microbial age may reduce cardiovascular disease (CVD) risk in metabolically unhealthy older adults.

14 Jun 2024

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy (RVCL).

13 Jun 2024

Empowering communities: Penn Medicine's annual mammogram event and health fair

Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.

13 Jun 2024

AI-driven alerts improve patient care escalation and survival rates in hospitals

Deploying and evaluating a machine learning intervention to improve clinical care and patient outcomes is a key step in moving clinical deterioration models from byte to bedside, according to a June 13 editorial in Critical Care Medicine that comments on a Mount Sinai study published in the same issue.

13 Jun 2024

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Early detection and treatment of hereditary transthyretin-related amyloidosis via genetic counseling are crucial.

13 Jun 2024

Antenatal COVID-19 vaccination shown to be safe for pregnant women and their babies

A study in Obstetrics & Gynecology finds that antenatal COVID-19 vaccination does not increase the risk of adverse pregnancy outcomes, confirming vaccine safety for pregnant women.

12 Jun 2024

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

A multi-centre, observational, prospective study was designed to evaluate the clinical usefulness of the systemic score in predicting life-threatening evolution – defined as the development of macrophage activation syndrome (MAS) and/or mortality.

12 Jun 2024

Innovative liver patch shows promise in tissue regeneration

As described in research published in the Biotechnology Journal, investigators have developed a novel patch that can help liver tissue regenerate.

12 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

Study uncovers gut microbes' role in childhood obesity

Researchers used Mendelian randomization to identify causal links between gut microbes and childhood obesity, revealing key microbial players that influence pediatric adiposity.

10 Jun 2024

New study reveals gut microbiome's critical role in aging and heart disease

Researchers in China discovered that gut microbiome diversity, influenced by metabolic health and age, significantly impacts cardiovascular disease risk.

9 Jun 2024

Berotralstat: A promising oral treatment for hereditary angioedema with normal C1-inhibitor

BioCryst Pharmaceuticals, Inc. today announced new real-world evidence showing that patients with hereditary angioedema (HAE) who have normal C1-inhibitor (HAE-nC1-INH) level and function had a reduction in monthly attack rates after starting oral, once-daily berotralstat.

8 Jun 2024

Novel Concepts Medical's plant-based formula achieves 99% reduction in cancer cell viability

Novel Concepts Medical is proud to announce breakthrough results from its labs in Israel showing that its plant-based formula resulted in over 99% decrease in cell viability of breast cancer cells and lung cancer cells.

8 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid - an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 - proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

Liver News and Research

Promising gene editing therapy shows hope in sickle cell disease cure

Short-term alcohol abstinence worsens gut health in alcohol use disorder patients

Younger gut microbiota age reduces cardiovascular disease risk in older adults

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

Empowering communities: Penn Medicine's annual mammogram event and health fair

AI-driven alerts improve patient care escalation and survival rates in hospitals

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Antenatal COVID-19 vaccination shown to be safe for pregnant women and their babies

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

Innovative liver patch shows promise in tissue regeneration

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Study uncovers gut microbes' role in childhood obesity

New study reveals gut microbiome's critical role in aging and heart disease

Berotralstat: A promising oral treatment for hereditary angioedema with normal C1-inhibitor

Novel Concepts Medical's plant-based formula achieves 99% reduction in cancer cell viability

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

How increased mTOR activity shortens lifespan and promotes aging-related diseases

New antioxidant biomaterial may provide relief to people living with chronic pancreatitis

Innovative therapeutic strategies for combating type 2 diabetes

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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