Proliferation News and Research

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Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Study: SphK2 enzyme regulates immune cell responses during viral infection

Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections.

11 Nov 2020

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver.

11 Nov 2020

Researchers discover unique anti-cancer function for previously well-characterized protein

The development and progression of cancer is a complicated process that occurs when cells in the body grow out of control. Many different mechanisms and pathways that directly affect cell proliferation have been uncovered.

10 Nov 2020

Study: Photoresponsive derivatives of Taxol allow light-based control of microtubule cytoskeleton

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have developed photoresponsive derivatives of the anticancer drug Taxol, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell division and may elucidate how Taxol acts.

9 Nov 2020

A new method to improve the preclinical evaluation of CAR T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies, in which the immune system's T cells are extracted from a patient, engineered to target a specific tumor-associated molecule and then grown and reinfused for cancer treatment.

6 Nov 2020

Machine-learning algorithm helps sort out huge amounts of data for protein research

Sorting huge amounts of data is a bottleneck in protein research, a field that is crucial to make use of the gene-editing technology CRISPR and fully understand diseases like cancer, Alzheimer's and Parkinson's

3 Nov 2020

Study proves how nitrate reduces blood pressure and improves oral health

The research team has patented one prebiotic compound and several probiotics with the identified molecules and bacteria.

3 Nov 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin Group 30 Oct 2020

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

Now, a team of researchers at the University of Florida report that the SARS-CoV-2 viroporin triggers the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome, which is responsible for the inflammatory pathology in severely ill COVID-19 patients.

30 Oct 2020

SMART researchers develop novel microcarrier for large-scale cell production

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have developed a novel microcarrier for large-scale cell production and expansion that offers higher yield and cost-effectiveness compared to traditional methods, and reduces steps required in the cell retrieval process.

29 Oct 2020

Moscow scientists discover and explain the activity mechanism of new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule -- diphenylisoxazole.

29 Oct 2020

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan.

29 Oct 2020

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Genetic factors that reduce the placenta's capacity to protect the fetus from the zika virus are described by Brazilian researchers in an article published in PLOS Neglected Tropical Diseases.

28 Oct 2020

Cellular senescence variations may control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Study finds new transposon-derived genes related to autism

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona, and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide.

27 Oct 2020

Happiness neurotransmitter serotonin plays role in evolutionary expansion of the neocortex

During human evolution, the size of the brain increased, especially in a particular part called the neocortex.

23 Oct 2020

Researchers find a new therapeutic approach to combat leukemia

Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, have found a new way to make these cells vulnerable by specifically dislodging these cells from their niches.

23 Oct 2020

DNA vaccine-induced antibodies neutralize SARS-CoV-2

The coronavirus disease (COVID-19) is far from over as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage across the globe. With the vast spread of the virus, many countries who reported flattening the curve over the past months have reported clusters of new cases and second waves of the outbreak.

22 Oct 2020

Proliferation News and Research

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Study: SphK2 enzyme regulates immune cell responses during viral infection

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Researchers discover unique anti-cancer function for previously well-characterized protein

Study: Photoresponsive derivatives of Taxol allow light-based control of microtubule cytoskeleton

A new method to improve the preclinical evaluation of CAR T cell therapies

Machine-learning algorithm helps sort out huge amounts of data for protein research

Study proves how nitrate reduces blood pressure and improves oral health

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

SMART researchers develop novel microcarrier for large-scale cell production

Moscow scientists discover and explain the activity mechanism of new anti-cancer molecule

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Researchers describe factors that reduce placenta's capacity to protect fetus from zika virus

Cellular senescence variations may control health and onset of age-related diseases

Study finds new transposon-derived genes related to autism

Happiness neurotransmitter serotonin plays role in evolutionary expansion of the neocortex

Researchers find a new therapeutic approach to combat leukemia

DNA vaccine-induced antibodies neutralize SARS-CoV-2

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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