in vivo News and Research

RSS

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

A new study analyzed the imprinted antibody responses towards the SARS-CoV-2 Omicron subvariants.

12 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an indicator for cancer and various other diseases.

10 May 2022

Potential antiviral targets in SARS-CoV-2

Researchers assessed potential targets in severe acute respiratory syndrome coronavirus 2.

6 May 2022

SARS-CoV-2 variants are not evolving to escape from T cell-mediated immunity

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants did not evolve further to escape from T cell-mediated immunity.

6 May 2022

Relevance of stem-loop 2 motif in SARS-CoV-2 and astroviruses

A recent paper posted to the bioRxiv* preprint server demonstrated that the stem-loop 2 motif (s2m) was substantial for astroviruses but unnecessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 May 2022

Injectable hydrogels for single-dose COVID-19 vaccination

Several coronavirus disease 2019 (COVID-19) vaccines require multiple doses for long-lasting immunity. However, a new study published in the journal Biomacromolecules has developed a promising single-dose vaccine platform using an injectable hydrogel containing an epitope-labeled plant virus, Cowpea mosaic virus (CPMV).

4 May 2022

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

In a recent study published in the journal Cell, researchers investigated distinguishing virological characteristics of Omicron sub-variant BA.2.

3 May 2022

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

A recent study under review at Nature Portfolio and posted to the Research Square* preprint server depicted how cellular nucleic acid-binding protein (CNBP) inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.

3 May 2022

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

A new study demonstrated the efficacy of the Galanthus nivalis agglutinin (GNA)-incorporated affinity resin against various SARS-CoV-2 variants.

3 May 2022

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

A new study analyzed multivalent messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine constructs against certain β-coronaviruses (β-CoVs).

3 May 2022

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

Carbon dots (CDs) are a kind of zero-dimensional carbonaceous nanomaterial. Due to their ultra-small size (usually less than 10 nm), simple synthesis, low toxicity, well-documented biocompatibility, and outstanding luminescent properties, CDs have attracted wild applications, particularly in bioimaging and biomedical fields.

3 May 2022

The generation of SARS-CoV-2 virus-like particles in insect cells

Researchers have reported the development of a promising COVID-19 vaccine candidate which is based on SARS-CoV-2 VLPs, derived from the co-expression of the spike, membrane, and envelope structural proteins in the baculovirus expression system.

2 May 2022

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

A recent research paper posted to the bioRxiv* preprint server demonstrated that a cocktail of two synergetic antibodies extensively neutralized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including Omicron BA.1 and BA.2.

1 May 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Study reveals new approach for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds.

29 Apr 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

in vivo News and Research

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

The promise of RNA medicine is targeted and personalized

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Potential antiviral targets in SARS-CoV-2

SARS-CoV-2 variants are not evolving to escape from T cell-mediated immunity

Relevance of stem-loop 2 motif in SARS-CoV-2 and astroviruses

Injectable hydrogels for single-dose COVID-19 vaccination

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

The generation of SARS-CoV-2 virus-like particles in insect cells

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

Probenecid shows activity against respiratory syncytial virus

Study reveals new approach for engineering stable articular cartilage

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Artificial circular RNAs found to bypass cellular antiviral responses

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News