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Study opens door to new approaches for preventing the development of metabolic diseases

The protein Asc-1 regulates whether fat-burning beige or fat-storing white adipocytes are formed, which can have an impact on the development of metabolic diseases.

31 Mar 2021

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Drinking flavanol-rich cocoa could protect from mental stress-induced cardiovascular events

Increased consumption of flavanols - a group of molecules occurring naturally in fruit and vegetables - could protect people from mental stress-induced cardiovascular events such as stroke, heart disease and thrombosis, according to new research.

31 Mar 2021

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

In a study recently published in the leading journal "Blood", Florian Moik and Cihan Ay from the Division of Hematology and Hemastasology of the Department of Medicine I of MedUni Vienna/Vienna General Hospital, working in collaboration with the Division of Oncology, the Department of Dermatology and the dispensary of Vienna General Hospital, provided preliminary data on the incidence, risk factors and clinical outcomes of thrombotic complications in this new form of cancer treatment.

31 Mar 2021

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Beckman Coulter life sciences brightens flow cytometry with new SuperNova polymer dyes portfolio

The world of flow cytometry is getting brighter as Beckman Coulter Life Sciences debuts its new SuperNova polymer dyes, featuring increased brightness and an improved staining index, which can enhance results in critical laboratory tests.

From Beckman Coulter Life Sciences - Flow Cytometry 31 Mar 2021

Early treatment with anti-VEGF injections slows diabetic retinopathy

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which usually begins at the onset of late disease.

31 Mar 2021

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.

31 Mar 2021

NIAID researchers identify key player in the immune response to SARS-CoV-2

When variants of SARS-CoV-2 (the virus that causes COVID-19) emerged in late 2020, concern arose that they might elude protective immune responses generated by prior infection or vaccination, potentially making re-infection more likely or vaccination less effective.

31 Mar 2021

Study shows how viral distribution of SARS-CoV-2 in the human body relates to tissue damage

Researchers have mapped the distribution of SARS-CoV-2, the virus that causes COVID-19, in deceased patients with the disease, and shed new light on how viral load relates to tissue damage.

31 Mar 2021

New study may lead to GRK5-based therapies to prevent heart failure

The human heart works under high demand, constantly pumping oxygen-rich blood through the body. When faced with disease, however, fulfilling this demand can become increasingly difficult and harmful.

31 Mar 2021

Combination of two existing drugs can kill cancer cells

Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic "hunger" of a particularly aggressive type of neuroblastoma to kill cancer cells without inflicting too much collateral damage to healthy tissue.

31 Mar 2021

Development of a model of substrate coordination to Zn-bound ACE2

The ongoing coronavirus disease-19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has claimed more than 2.8 million lives worldwide. Authorities are facing difficulty in preventing the spread of disease due to the highly infectious nature of SARS-CoV-2. Therefore, reducing the virus's ability to infect an individual's respiratory epithelial cells could prove an effective measure to prevent disease transmission.

31 Mar 2021

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

Twins may look alike on the outside, but not so much on the inside. That's one takeaway from a new preprint study posted to the medRxiv server where Brazilian researchers observed different T-cell responses in two pairs of identical twins exposed to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One twin who was reinfected with SARS-CoV-2 four months after had low recognition of CD4+ and CD8+ T-cell epitopes.

31 Mar 2021

Mice study provides insight into the beneficial effects of selenium supplementation

Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a study published today in eLife.

30 Mar 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

Blood News and Research

Study opens door to new approaches for preventing the development of metabolic diseases

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Drinking flavanol-rich cocoa could protect from mental stress-induced cardiovascular events

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Beckman Coulter life sciences brightens flow cytometry with new SuperNova polymer dyes portfolio

Early treatment with anti-VEGF injections slows diabetic retinopathy

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

NIAID researchers identify key player in the immune response to SARS-CoV-2

Study shows how viral distribution of SARS-CoV-2 in the human body relates to tissue damage

New study may lead to GRK5-based therapies to prevent heart failure

Combination of two existing drugs can kill cancer cells

Development of a model of substrate coordination to Zn-bound ACE2

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

Mice study provides insight into the beneficial effects of selenium supplementation

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Using a salt substitute can help lower blood pressure in rural India

Drinking beetroot juice promotes oral bacteria linked to healthier blood vessels and brain function

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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