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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New database provides easy access to information about genes and biological functions

The human genome sequence, initially completed in draft form nearly a decade ago, has revolutionized biological research. But most research findings are buried in the scientific literature, and linking basic biological processes to genomic information can be difficult without substantial effort or training. A new resource that provides easy access to information about genes and their biological functions was just released by Cold Spring Harbor Laboratory Press.

12 Jan 2011

Life Technologies announces new DNA sequencing portfolio for lab research

Life Technologies Corporation today announced a series of new product innovations across the company's DNA sequencing portfolio. To date, most sequencing technologies have primarily addressed the needs of researchers in the highest throughput laboratories, limiting widespread accessibility of these powerful next-generation sequencing technologies.

12 Jan 2011

CAMH scientists receive NARSAD's Young Investigator grant awards for brain and behavior research

Seven scientists at Canada's Centre for Addiction and Mental Health have been awarded Young Investigator grant awards by the U.S.-based NARSAD: The Brain and Behavior Research Fund.

12 Jan 2011

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

Merck today announced that the New Drug Application (NDA) for the Company's investigational extended-release formulation of JANUMET for type 2 diabetes has been accepted for standard review by the U.S. Food and Drug Administration (FDA). The Company is also moving forward as planned with regulatory filings in countries outside the United States.

12 Jan 2011

Cyclacel opens enrollment of sapacitabine Phase 3 trial for AML

Cyclacel Pharmaceuticals, Inc., today announced that it has opened enrollment of the SEAMLESS pivotal Phase 3 trial for the Company's sapacitabine oral capsules as a front-line treatment of elderly patients aged 70 years or older with newly diagnosed acute myeloid leukemia (AML) who are not candidates for intensive induction chemotherapy.

11 Jan 2011

Positive results from Allovectin-7 Phase 3 trial in patients with metastatic melanoma

Vical Incorporated today announced a new publication summarizing results from the company's completed trials of Allovectin-7 including systemic responses and an excellent safety profile in patients with metastatic melanoma.

11 Jan 2011

Survey reveals rise in Americans' concern over privacy of genetic information

A report just released by Cogent Research, in partnership with CAHG, reveals that Americans are more concerned than ever about the privacy of their genetic information. Furthermore, this concern is increasingly inhibiting the likelihood that they will consider having a molecular diagnostic test. These and other findings are explored in more detail in the 5th edition of the Cogent Genomics, Attitudes & Trends study (CGAT 2010).

11 Jan 2011

Inhibiting miR-193a decreases tumor growth in SCC

Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback loop between p63, microRNAs (miRs), and p73. In a model of SCC, they found that inhibiting one of these miRs decreased tumor growth and made the cells more sensitive to chemotherapy, highlighting a new potential therapeutic target.

11 Jan 2011

QIAGEN to acquire minority stake in Alacris Theranostics

QIAGEN has signed an agreement for the acquisition of a strategic stake in Alacris Theranostics GmbH, a German start-up company using novel technologies to develop individualized cancer treatment strategies based upon a patient's genomic profile, and for the acquisition of an exclusive option to access all biomarkers emerging from this discovery program.

From QIAGEN Manchester Limited 11 Jan 2011

Silicon microdevices may provide new way to screen metastatic breast cancer cells

Research by engineers and cancer biologists at Virginia Tech indicate that using specific silicon microdevices might provide a new way to screen breast cancer cells' ability to metastasize.

11 Jan 2011

Nationwide Children's Hospital receives $11.5 million NCI grant for Biospecimen banking

Nationwide Children's Hospital was awarded $11.5 million from the National Cancer Institute late last year to continue its role as one of two Biospecimen Core Resources for The Cancer Genome Atlas.

11 Jan 2011

Study: Protein that plays a key role in some antioxidant therapies can promote atherosclerosis

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries.

11 Jan 2011

Multiple sclerosis gene connection from women to offspring: Study

A new study has shown that women pass on the multiple sclerosis (MS) gene more commonly than men to their offspring. The team analyzed DNA of more than 7,000 people and found that women were also more likely to pass on the gene to female relatives. This may explain why women are up to three times more likely to get MS than men. The study was funded by the MS Society and led by George Ebers at Oxford University. It was published in the journal Neurology.

10 Jan 2011

All fat cells not the same

All fat cells are not the same - a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).

10 Jan 2011

Sangamo completes enrollment in SB-509-901 Phase 2b clinical trial in diabetic neuropathy

Sangamo BioSciences, Inc. announced today that the company completed enrollment of its Phase 2b double-blind, placebo-controlled clinical trial (SB-509-901) in subjects with diabetic neuropathy (DN). The company expects to have efficacy data from this study in the second half of 2011. The company also plans to present the first human clinical data from its Phase 1 trials of SB-728-T in HIV/AIDS in the first quarter of 2011.

10 Jan 2011

Illumina announces next generation of iSelect custom genotyping products

Illumina, Inc. today announced its next generation of iSelect custom genotyping products that allow researchers to design custom arrays containing from 3,000 up to 1,000,000 markers, with the flexibility to add supplemental content to their array designs.

From Illumina, Inc. 10 Jan 2011

Positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C virus

Inovio Pharmaceuticals, a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today the publication of a scientific paper highlighting positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C viruses in the journal Vaccine.

10 Jan 2011

Professor Puchta receives ERC's Advanced Researcher Grant

Tomatoes that resist pests and extreme weather while still tasting like tomatoes are among Professor Holger Puchtas long-term research goals. The molecular biologist develops techniques that will allow him to control inheritance in plants to selectively improve the properties of different species through nature's existing gene pool. For his fundamental research, Puchta now is awarded an Advanced Researcher Grant by the European Research Council.

10 Jan 2011

Innovative device reduces dental drill's noise, helps people to seek oral healthcare treatment

An innovative device which cancels out the noise of the dental drill could spell the end of people's anxiety about trips to the dentist, according to experts at King's College London, Brunel University and London South Bank University, who pioneered the invention.

10 Jan 2011

Specific silicon microdevices may provide new way to screen metastatic breast cancer cells

Research by engineers and cancer biologists at Virginia Tech indicate that using specific silicon microdevices might provide a new way to screen breast cancer cells' ability to metastasize.

9 Jan 2011

DNA News and Research

Further Reading

New database provides easy access to information about genes and biological functions

Life Technologies announces new DNA sequencing portfolio for lab research

CAMH scientists receive NARSAD's Young Investigator grant awards for brain and behavior research

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

Cyclacel opens enrollment of sapacitabine Phase 3 trial for AML

Positive results from Allovectin-7 Phase 3 trial in patients with metastatic melanoma

Survey reveals rise in Americans' concern over privacy of genetic information

Inhibiting miR-193a decreases tumor growth in SCC

QIAGEN to acquire minority stake in Alacris Theranostics

Silicon microdevices may provide new way to screen metastatic breast cancer cells

Nationwide Children's Hospital receives $11.5 million NCI grant for Biospecimen banking

Study: Protein that plays a key role in some antioxidant therapies can promote atherosclerosis

Multiple sclerosis gene connection from women to offspring: Study

All fat cells not the same

Sangamo completes enrollment in SB-509-901 Phase 2b clinical trial in diabetic neuropathy

Illumina announces next generation of iSelect custom genotyping products

Positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C virus

Professor Puchta receives ERC's Advanced Researcher Grant

Innovative device reduces dental drill's noise, helps people to seek oral healthcare treatment

Specific silicon microdevices may provide new way to screen metastatic breast cancer cells

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