Immune System News and Research

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Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

14 Sep 2011

STED microscope reveals that F-actin pervades immunological synapse

Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.

14 Sep 2011

'Achilles' heels' within HCV virus

Hopes for an effective vaccine and treatment against the potentially fatal hepatitis C virus (HCV) have received a major boost following the discovery of two 'Achilles' heels' within the virus.

14 Sep 2011

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Accentia Biopharmaceuticals, Inc. and its majority-owned subsidiary, Biovest International, Inc., today jointly announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to Revimmune, the Company's proprietary system-of-care based on high-dose administration of Cytoxan, for the prevention of graft-versus-host disease (GVHD) following bone marrow transplant.

14 Sep 2011

Inovio achieves best-in-class immune responses in PENNVAX-B HIV vaccine Phase I study

Inovio Pharmaceuticals, Inc., a leader in the development of synthetic immunogens against cancers and infectious diseases, announced today that it has achieved best-in-class immune responses in a Phase I clinical study of PENNVAX-B, its product for the prevention of the HIV sub-type prevalent in the US and Europe.

14 Sep 2011

Rwanda to treat HIV-positive people in discordant relationships as soon as they test positive

After a landmark study published in May "showed major reductions in HIV transmission among discordant couples due to early treatment," Rwanda has decided to begin treating people in discordant relationships with antiretroviral therapy as soon as they test HIV-positive "as part of a plan to boost national HIV prevention and treatment efforts," PlusNews reports.

14 Sep 2011

IUDs may protect from cervical cancer

According to the results of an international study, coil contraceptive devices might protect women against developing cervical cancer even though they don't stop the infection that commonly leads to the disease.

14 Sep 2011

Computer models that predict response to treatment

Details of computer models that can predict the chances of a patient responding to their HIV drugs with 80% accuracy are published today in the journal AIDS. The models were developed by the HIV Resistance Response Database Initiative (RDI) using almost half a million pieces of data from approximately 6,000 clinical cases from hundreds of clinics around the world. The models are now available online as part of an experimental treatment support tool, HIV-TRePS.

14 Sep 2011

Intrauterine devices may lower risk of cervical cancer among users, study shows

Contraceptive intrauterine devices (IUDs), also called coils, "might actually protect women against developing cervical cancer even though they don't stop the infection that commonly leads to the disease," according to a study published Tuesday in the journal Lancet Oncology, Reuters reports.

14 Sep 2011

Intrauterine devices may protect against cervical cancer

Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date in which has participated the research group in Viruses and Cancer of IDIBELL, published at The Lancet Oncology.

14 Sep 2011

Positive data from NovaDigm's NDV-3 vaccine program to be presented at ICAAC conference

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced that the Company will present positive data for its NDV-3 vaccine program at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), taking place September 17-20, 2011 in Chicago, IL.

13 Sep 2011

ImmunoCellular announces updated long-term data from ICT-107 Phase I trial on GBM

ImmunoCellular Therapeutics, Ltd., a biotechnology company focused on the development of novel immune-based cancer therapies, today announced updated long-term data from a Phase I clinical trial of ICT-107, the Company's lead cancer vaccine candidate for the treatment of glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer.

13 Sep 2011

Breakthrough opens new avenues for hep C vaccine

Hopes for an effective vaccine and treatment against the potentially fatal hepatitis C virus (HCV) have received a major boost following the discovery of two ‘Achilles’ heels’ within the virus.

12 Sep 2011

Researchers identify glucokinase triggers beta cell regeneration in pancreas

Researchers at the Hebrew University of Jerusalem have identified the key signal that prompts production of insulin-producing beta cells in the pancreas -- a breakthrough discovery that may ultimately help researchers find ways to restore or increase beta cell function in people with type 1 diabetes.

12 Sep 2011

JHUSON nursing research news

In a six-month, randomized controlled study of asthmatic children living with smokers reported in the Archives of Pediatrics and Adolescent Medicine, August 2011, Johns Hopkins University School of Nursing (JHUSON) professor and School of Medicine faculty member Arlene Butz, MSN, CPNP, ScD, and others found that regular use of indoor air cleaners can greatly reduce household air pollution and lower rates of children's daytime asthma symptoms.

12 Sep 2011

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at the University of Maryland School of Medicine Center for Vaccine Development.

12 Sep 2011

Pharmacologists study first drug-resistant strain of pneumonia to enter Texas

A team of researchers from the University of Houston (UH) and St. Luke's Episcopal Hospital (SLEH) are working to develop improved screening methods to detect a potentially lethal, drug-resistant superbug that has made its way to Texas.

9 Sep 2011

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have made a landmark discovery in the battle against the rapid spread of aggressive cancers associated with PRL-3 oncoprotein.

9 Sep 2011

Novel solution for purifying stem cell mixtures

Stem cells show great potential to enable treatments for conditions such as spinal injuries or Lou Gehrig's disease, and also as research tools. One of the greatest problems slowing such work is that researchers have found major complications in purifying cell mixtures, for instance to remove stem cells that can cause tumors from cells developed for use in medical treatments.

9 Sep 2011

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

The Juvenile Diabetes Research Foundation (JDRF), the worldwide leader for research to cure, treat, and prevent type 1 diabetes, and InnoCentive, Inc., the pioneer in open innovation and crowdsourcing, today announced a $100,000 Challenge calling for innovative ways to approach the discovery and development of a glucose-responsive insulin drug as a means to treat insulin-dependent diabetes.

9 Sep 2011

Immune System News and Research

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

STED microscope reveals that F-actin pervades immunological synapse

'Achilles' heels' within HCV virus

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Inovio achieves best-in-class immune responses in PENNVAX-B HIV vaccine Phase I study

Rwanda to treat HIV-positive people in discordant relationships as soon as they test positive

IUDs may protect from cervical cancer

Computer models that predict response to treatment

Intrauterine devices may lower risk of cervical cancer among users, study shows

Intrauterine devices may protect against cervical cancer

Positive data from NovaDigm's NDV-3 vaccine program to be presented at ICAAC conference

ImmunoCellular announces updated long-term data from ICT-107 Phase I trial on GBM

Breakthrough opens new avenues for hep C vaccine

Researchers identify glucokinase triggers beta cell regeneration in pancreas

JHUSON nursing research news

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

Pharmacologists study first drug-resistant strain of pneumonia to enter Texas

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Novel solution for purifying stem cell mixtures

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

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