Metabolites News and Research

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Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Scientist wins award for research in the field of commensal microbiota

The winner of the Johanna Duermueller-Bol DBMR Research Award 2018 is Dr. Stephanie Ganal-Vonarburg. As a Senior Scientist, she conducts research in the Gastroenterology / Mucosal Immunology Research Laboratory at Bern University Hospital and at the Department for BioMedical Research at the University of Bern.

8 Nov 2018

Researchers develop technique to disrupt communication between microorganisms

The World Health Organization considers Pseudomonas aeruginosa a germ requiring urgent action to prevent and control its spread. The bacteria can cause a variety of diseases from chronic lung infections to sepsis.

8 Nov 2018

New method helps study connection between metabolism in gut bacteria and development of diabetes

Researchers at örebro University have, together with a well-known research team in Denmark, developed a method for studying how metabolism in gut bacteria influences our health. Their method will now be published in its entirety in the scientific journal Nature Protocols.

7 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

Organ-on-a-chip model helps explore underlying pathways shared by stroke and dementia

Stroke is the second main cause of death globally, and a major cause of disability. Around 15 million people worldwide suffer a stroke each year, and rates are climbing, with the number of strokes in Europe set to increase by 1.5 million per year by 2025 – due in large part to the aging population.

29 Oct 2018

Study provides a new way of thinking about cold stress in plants

When temperatures drop, plants can't bundle up. Stuck outside, exposed, plants instead undergo a series of biochemical changes that protect cells from damage.

29 Oct 2018

Study finds cluster of factors that may help predict C. diff infections

A cluster of factors may help predict which patients are likely to develop Clostridioides difficile, a potentially life-threatening disease commonly known as C. difficile or C. diff, a new study has found.

25 Oct 2018

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Myocardial infarction is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, cell death occurs.

15 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Scientists find new way to predict obesity-related disease risk

Scientists at Scripps Research and collaborating corporate and academic partners have found a new way to use distinct molecular "signatures" from people with obesity to predict risk of developing diabetes and cardiovascular disease, an advance that could broaden the way doctors and scientists think about diagnosing and treating disease.

12 Oct 2018

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

University of Houston biologist Michihisa Umetani, having discovered that a certain protein partnership acts to rapidly signal molecules inside blood vessels that danger is upon them, has been awarded $382,500 by the National Institutes of Health.

10 Oct 2018

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Leadiant Biosciences, Inc. today announced that the Food and Drug Administration has granted approval to Revcovi (elapegademase-lvlr) injection in the U.S. Revcovi is a new enzyme replacement therapy for the treatment of adenosine deaminase severe combined immune deficiency in pediatric and adult patients.

7 Oct 2018

Fruit fly protein shows protective effect on dopamine-producing neurons

Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness.

3 Oct 2018

Newly discovered compounds may explain whole grain health benefits

Scientists have discovered new compounds that may explain whole grain health benefits, reports a new study led by the University of Eastern Finland.

3 Oct 2018

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Vitamin E's positive effects often fail to manifest themselves as strongly as expected, but sometimes administering vitamin E actually has detrimental effects. An international team has now found a possible cause for this.

3 Oct 2018

Natural nanoscopic particles identified as possible diagnostic tool for Alzheimer's

Exosomes are natural nanoscopic particles released by most cell types, and are currently the focus of research because they represent a possible tool for the diagnosis of Alzheimer's. These particles are not so easy to isolate, and nanotechnology may help in this process.

3 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Metabolites News and Research

Researchers develop powerful method to solve structures of small molecules

Scientist wins award for research in the field of commensal microbiota

Researchers develop technique to disrupt communication between microorganisms

New method helps study connection between metabolism in gut bacteria and development of diabetes

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

Organ-on-a-chip model helps explore underlying pathways shared by stroke and dementia

Study provides a new way of thinking about cold stress in plants

Study finds cluster of factors that may help predict C. diff infections

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Metabolome tests could be new way to measure obesity and health

Scientists find new way to predict obesity-related disease risk

Researchers uncover how common pain reliever causes liver failure

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Fruit fly protein shows protective effect on dopamine-producing neurons

Newly discovered compounds may explain whole grain health benefits

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Natural nanoscopic particles identified as possible diagnostic tool for Alzheimer's

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

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