Inflammation News and Research

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Cytrx’s study offers a better perception of arimoclomol's mechanism of action in induced animal stroke

CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, today announced that study results demonstrated that arimoclomol exhibited both statistically significant neuroprotective and neuroregenerative effects in brain cells of animals induced with stroke, offering important insights into this drug candidate’s mechanism of action.

25 Aug 2009

Study reveals that treating Alzheimer's disease with DHA and EPA slows down its progression

Scientists have identified the inflammatory process as the common soil in a diverse range of chronic degenerative diseases. The news, recently reported in the LA Times article, discusses how foods like cherries may help rheumatoid arthritis or avoidance of gluten may fight off psoriasis.

24 Aug 2009

Research reveals that diarrheal bacteria can cause colon cancers

Johns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers. The investigators say that strains of the common Bacteroides fragilis (ETBF) dupe immune system cells into permitting runaway colon tissue inflammation, a precursor for malignant growth.

24 Aug 2009

Diabetics can reduce the risk of cardiovascular disease by increasing vitamin D levels

Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know why.

24 Aug 2009

Ron Demuth of ChemDiv announces extension of collaboration with Lilly

ChemDiv, Inc. announced the expansion of its drug discovery collaboration with Eli Lilly through 2010. Under the terms of the agreement, the partners will identify and develop leads for an additional therapeutic target using ChemDiv's small molecule resources (the industry's largest commercial collection) and Discovery outSource™ drug discovery and development platforms.

21 Aug 2009

Exhaled nitric oxide needs to be measured in asthma patients

CareFirst BlueCross BlueShield, the largest health care insurer in the Mid-Atlantic region of the USA, has adopted a policy stating that measurement of exhaled nitric oxide (eNO) is considered medically necessary in the management of asthma patients.

21 Aug 2009

West Nile Virus threat continues in Pennsylvania

Department of Environmental Protection Secretary John Hanger today reminded Pennsylvania's citizens that although the number of West Nile Virus cases has dropped, the threat still exists.

21 Aug 2009

Research attributes accumulation of belly fat to change in hormone balance during menopause transition

In middle-aged women, visceral fat, more commonly called belly fat, is known to be a significant risk factor for cardiovascular disease, but what causes visceral fat to accumulate?

21 Aug 2009

Genetic engineering technique used to treat bowel disorders

For the first time, scientists have used a genetically engineered "friendly" bacterium to deliver a therapy.

21 Aug 2009

Duke University Medical Center highlights importance of the appendix in human body

The lowly appendix, long-regarded as a useless evolutionary artifact, won newfound respect two years ago when researchers at Duke University Medical Center proposed that it actually serves a critical function. The appendix, they said, is a safe haven where good bacteria could hang out until they were needed to repopulate the gut after a nasty case of diarrhea, for example.

21 Aug 2009

Consumer-friendly "finger stick" blood test to detect cardiovascular disease is broadly available now

A new blood test, measuring the level of omega-3 fatty acids in red blood cells, is now broadly available for the first time to the public everywhere as a consumer-friendly, at-home "finger stick" test. While scientists have long known of the benefits of fish and fish oil for overall heart health, over the past decade research has proven that the omega-3 fatty acids found in fish dramatically reduce one's risk for cardiovascular disease. Further, recent research indicates that omega-3 levels may be among the best predictors of future coronary heart disease - providing much stronger correlations to the risk of sudden cardiac death than traditional indicators, including HDL and LDL cholesterol.

20 Aug 2009

UT Southwestern Medical Center: Human gut bacteria ward off Toxoplasma gondii

Immunology researchers at UT Southwestern Medical Center have found that bacteria present in the human gut help initiate the body's defense mechanisms against Toxoplasma gondii, the parasite responsible for toxoplasmosis.

20 Aug 2009

Study finds long-term exposure to progesterone may lead to growth of tumors

Scientists at Michigan State University have found exposure to the hormone progesterone activates genes that trigger inflammation in the mammary gland.

20 Aug 2009

Study unveils detrimental effects of high-dose ursodeoxycholic acid on patients with PSC

Primary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period. PSC is a common cause of adult cholestatic liver diseases and a primary source behind many of the liver transplantations in U.S. adults. At least 70% of PSC cases are associated with chronic inflammatory bowel disease (IBD), usually ulcerative colitis. Currently, there is no cure for PSC and prospective treatments remain ineffective.

20 Aug 2009

U.S. FDA approval of miconazole MBT represents a significant milestone for Strativa Pharmaceuticals

Strativa Pharmaceuticals, the proprietary products division of a wholly owned subsidiary of Par Pharmaceutical Companies, Inc. (NYSE: PRX), today announced that the U.S. Food and Drug Administration (FDA) has accepted the new drug application (NDA) for miconazole Lauriad((R)) mucoadhesive buccal tablets (MBT) to treat oropharyngeal candidiasis (OPC).

19 Aug 2009

Researchers find connection between eye disease and arginase

Elevated levels of the enzyme arginase contribute to vascular eye damage and Medical College of Georgia researchers say therapies to normalize its levels could halt progression of potentially blinding diseases such as diabetic retinopathy.

19 Aug 2009

BioAlliance Pharma's new drug application for oropharyngeal candidiasis treatment accepted by the FDA

BioAlliance Pharma SA (Paris:BIO), a company dedicated to the treatment and supportive care of cancer and AIDS patients, today announced that the U.S. Food and Drug Administration (FDA) has accepted the new drug application (NDA) for miconazole Lauriad® (Loramyc®) Mucoadhesive Buccal Tablets (MBT) to treat oropharyngeal candidiasis (OPC). Miconazole Lauriad® delivers the antifungal miconazole via a mucoadhesive buccal tablet that is designed to enable once-daily dosing of the active ingredient at the site of infection.

19 Aug 2009

Research study highlights the biological importance of Vitamin D in humans and other primates

A new study has concluded that one key part of the immune system, the ability of vitamin D to regulate anti-bactericidal proteins, is so important that is has been conserved through almost 60 million years of evolution and is shared only by primates, including humans - but no other known animal species.

19 Aug 2009

Aerocrine allowed to add a third patent to its infringment complaint against Apieron

Aerocrine AB today announced that the United States District Court has accepted Aerocrine’s motion for leave to add a third patent to its October 2008 patent infringement complaint against Apieron, Inc. Menlow Park, USA.

19 Aug 2009

Fatigue during radiotherapy for breast or prostate cancer may be caused by inflammation

Patients who experience fatigue during radiotherapy for breast or prostate cancer may be reacting to activation of the proinflammatory cytokine network, a known inflammatory pathway, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

19 Aug 2009

Inflammation News and Research

Cytrx’s study offers a better perception of arimoclomol's mechanism of action in induced animal stroke

Study reveals that treating Alzheimer's disease with DHA and EPA slows down its progression

Research reveals that diarrheal bacteria can cause colon cancers

Diabetics can reduce the risk of cardiovascular disease by increasing vitamin D levels

Ron Demuth of ChemDiv announces extension of collaboration with Lilly

Exhaled nitric oxide needs to be measured in asthma patients

West Nile Virus threat continues in Pennsylvania

Research attributes accumulation of belly fat to change in hormone balance during menopause transition

Genetic engineering technique used to treat bowel disorders

Duke University Medical Center highlights importance of the appendix in human body

Consumer-friendly "finger stick" blood test to detect cardiovascular disease is broadly available now

UT Southwestern Medical Center: Human gut bacteria ward off Toxoplasma gondii

Study finds long-term exposure to progesterone may lead to growth of tumors

Study unveils detrimental effects of high-dose ursodeoxycholic acid on patients with PSC

U.S. FDA approval of miconazole MBT represents a significant milestone for Strativa Pharmaceuticals

Researchers find connection between eye disease and arginase

BioAlliance Pharma's new drug application for oropharyngeal candidiasis treatment accepted by the FDA

Research study highlights the biological importance of Vitamin D in humans and other primates

Aerocrine allowed to add a third patent to its infringment complaint against Apieron

Fatigue during radiotherapy for breast or prostate cancer may be caused by inflammation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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