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New computational pipeline identifies key biomarkers for Alzheimer's disease

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD).

6 Dec 2024

New study links specific E. coli strains to higher cancer incidence rates

Higher rates of certain cancers in countries, such as the UK, may be linked to two particular strains of bacteria.

6 Dec 2024

AI predicts mortality with whole-body MRI for personalized health insights

Researchers developed a deep learning framework for whole-body MRI-based body composition analysis, predicting mortality more accurately than traditional methods. This innovative approach could revolutionize personalized risk assessments and clinical workflows.

5 Dec 2024

Phase one trial explores novel immunotherapy for breast cancer

A groundbreaking phase one clinical trial exploring a novel cell-based immunotherapy for breast cancer has been accepted for publication in JAMA Oncology.

5 Dec 2024

Psilocybin helps reduce depression in clinicians amid COVID-19 crisis

Psilocybin-assisted psychotherapy resulted in significant reductions in depression among clinicians who provided front-line COVID-19 care in 2020 and 2021.

5 Dec 2024

Cancer prevention and screening avert more deaths than treatment advances

Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study led by researchers at the National Institutes of Health (NIH).

5 Dec 2024

EZH2 inhibitors enhance effectiveness of cancer immunotherapies

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

5 Dec 2024

New risk score accurately predicts cardiovascular events in women

A new risk score accurately predicts and categorizes the risk of major adverse cardiovascular events, such as heart attack, in women. The findings were published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA).

5 Dec 2024

Bioengineers develop implantable sensors to monitor inflammation in real time

Proteins are the building blocks of life, and changes in protein levels can indicate improving health or impending illness, including signs of inflammation.

5 Dec 2024

KFF Health News' 'What the Health?': A colorful cast could lead key health agencies

President-elect Donald Trump has continued naming out-of-the-box choices to lead key federal health agencies.

5 Dec 2024

Activating a protein signaling pathway slows prostate cancer growth

A special protein can play a key role in the fight against certain types of prostate cancer. This is shown in a study by an international research group led from Umeå University, Sweden.

5 Dec 2024

Early ovarian removal and APOE4 increase Alzheimer's risk in women

New research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

5 Dec 2024

Deforestation undermines malaria prevention efforts

When a forest is lost to development, some effects are obvious. Stumps and mud puddles across the landscape, a plowed field or houses a year after that.

5 Dec 2024

Scientists link proteins to Alzheimer’s through cutting-edge genetic method

Researchers have developed MR-SPI, a novel method integrated with AlphaFold3, to identify causal protein biomarkers and predict their 3D structural changes in Alzheimer’s disease. This breakthrough offers insights into disease mechanisms and potential therapeutic targets.

5 Dec 2024

Frontotemporal dementia disrupts empathy for pain, study reveals

Study reveals diminished brain activity related to empathy for pain in individuals with behavioral variant frontotemporal dementia (bvFTD), using task-based fMRI. Findings show a stark reduction in neural responses tied to affective empathy, highlighting early bvFTD impacts on social cognition.

5 Dec 2024

Can AI fix the peer review bottleneck? Top journals weigh in

Study examines AI's role in peer review among top 100 medical journals, revealing that while most journals provide AI guidelines, a majority prohibit its use due to confidentiality and ethical concerns. The findings highlight varied policies and emphasize the need for clear, unified guidance for AI integration in peer review.

5 Dec 2024

Study sheds light on Kif23's role in embryonic brain development and microcephaly

A team of researchers from Tohoku University, the National Center of Neurology and Psychiatry, and National Yang Ming Chiao Tung University has uncovered a novel molecular mechanism through which Kif23 (a motor protein belonging to the kinesin family) plays a vital role in embryonic brain development.

5 Dec 2024

Long-COVID lingers in children

A 24-month study reveals that 7.2% of children consistently experience long-COVID symptoms, with tiredness, sleep issues, and headaches most commonly reported, highlighting the need for targeted interventions.

5 Dec 2024

Dupilumab improves symptoms of atopic dermatitis in children with co-existing conditions

Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies.

5 Dec 2024

New framework enhances genetic prediction of drug response and side effects

A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side effects.

5 Dec 2024