Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

FDA approves RiaSTAP for bleeding in patients with congenital fibrinogen deficiency

The U.S. Food and Drug Administration has licensed RiaSTAP, an orphan drug for the treatment of bleeding in patients with a rare genetic defect known as congenital fibrinogen deficiency. Without treatment, these patients are at risk of potentially life-threatening bleeding.

18 Jan 2009

New diagnostic tool to measure blood flow could prevent needless stents

Doctors may be implanting too many artery-opening stents and could improve patient outcomes - and ultimately save lives - if they did more in-depth measurements of blood flow in the vessels to the heart.

15 Jan 2009

Morbidly obese patients face high risk for complications after colectomy

New research published in the January issue of the Journal of the American College of Surgeons shows that morbidly obese patients are at higher risk than normal weight patients for complications after colectomy ¨C surgical removal of all or part of the colon ¨C for the treatment of cancer.

15 Jan 2009

Oral contraceptives may be safe, but information gaps remain

Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives.

15 Jan 2009

Schering-Plough announces European submission of fertility medicine Corifollitropin Alfa

Schering-Plough Corp. has announced that the European Medicines Agency (EMEA) has validated (accepted for review) its Marketing Authorization Application (MAA) for corifollitropin alfa, the company's experimental, sustained follicle stimulant (SFS).

1 Jan 2009

FDA to review prasugrel for acute coronary syndromes

Daiichi Sankyo Company, Limited and Eli Lilly and Company has confirmed that the U.S. Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC) will review prasugrel during an advisory committee hearing on February 3, 2009.

1 Jan 2009

Seniors warned about mixing OTC and prescription drugs

According to researchers in the United States about 2.2 million seniors put themselves at high risk for drug interactions - they say many non-prescription medication, which are bought over-the-counter (OTC) can produce a harmful drug interactions.

29 Dec 2008

Stem cells and leukemia battle for marrow microenvironment

Learning how leukemia takes over privileged "niches" within the bone marrow is helping researchers develop treatment strategies that could protect healthy blood-forming stem cells and improve the outcomes of bone marrow transplantation for leukemia and other types of cancer.

18 Dec 2008

New method offers direct access to the brain through the nose to treat stroke

UT Health Science Center San Antonio researchers, working in a mouse model of stroke, are delivering neuroprotective drugs to the brain by spraying them onto the lining of a nerve in the nose.

18 Dec 2008

Surgeons perform first simultaneous double-lung, kidney transplant in Illinois, Wisconsin

Eric McCabe of Wausau, Wis., had no earth-shaking plans for the future as he began his recovery from the rare double-lung and kidney transplant surgery he had at Loyola University Medical Center in Maywood, Ill.

17 Dec 2008

Hospitals using quality improvement program increase compliance to stroke treatment guidelines

Hospitals participating in a voluntary quality improvement program for stroke treatment increased adherence to national recommendations, researchers reported in Circulation: Journal of the American Heart Association.

15 Dec 2008

Carbon monoxide used to protect mouse nerve cells from damage

Researchers at Johns Hopkins have shown that brain damage was reduced by as much as 62.2 percent in mice who inhale low amounts of carbon monoxide after an induced stroke.

15 Dec 2008

Portola Pharmaceuticals starts phase 2 trial of P2Y12 ADP receptor antagonist in non-urgent percutaneous coronary intervention

Portola Pharmaceuticals has announced that it has initiated patient enrollment in INNOVATE-PCI, a large Phase II clinical trial of PRT060128, the Company's novel P2Y12 ADP receptor antagonist, in patients undergoing non-urgent percutaneous coronary intervention (PCI).

10 Dec 2008

Drug combo improves or stabilizes disease for relapsed multiple myeloma patients

Mayo Clinic researchers have found that a new combination of medications designed to maximize immune functions improved or stabilized multiple myeloma for 76 percent of patients who had relapsed after previous treatment.

10 Dec 2008

Protein could prevent blocked arteries

For the first time, researchers have found that a modified form of a naturally occurring protein, N-cadherin, could prevent blocked arteries. Blocked arteries are a major cause of heart attacks and strokes.

10 Dec 2008

Recombinant human antithrombin drug decreases risk to pregnancy and surgery patients with hereditary antithrombin deficiency

Pregnancy and surgery patients with a serious blood disorder that causes excessive clotting have responded well to treatment with a man-made anti-clotting protein.

8 Dec 2008

New approaches to prevent blood clots

The largest study ever to examine the preventive use of blood-thinning medication to help prevent deadly blood clots in patients with cancer undergoing chemotherapy presented December 7 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

Daiichi Sankyo starts trial of investigational factor Xa inhibitor for atrial fibrillation

Daiichi Sankyo Company, Limited, has announced that it has initiated its pivotal Phase III trial for DU-176b, an investigational oral Factor Xa inhibitor, in patients with atrial fibrillation. DU-176b is being developed solely by Daiichi Sankyo.

7 Dec 2008

ACE inhibitor calcium channel blocker combo drug shown to reduces heart attacks

While doctors are urged to start with a diuretic-based strategy to control patients' high blood pressure, an international blood pressure study shows a different single-pill drug combination is more effective at preventing heart-related events such as heart attacks and strokes.

3 Dec 2008

Discovery of new enzyme in cancer growth

While studying the mechanics of blood clots, researchers at the University of Oklahoma Health Sciences Center discovered a new enzyme that not only affects the blood, but seems to play a primary role in how cancer tumors expand and spread throughout the body.

3 Dec 2008

Blood Clot News and Research

Further Reading

FDA approves RiaSTAP for bleeding in patients with congenital fibrinogen deficiency

New diagnostic tool to measure blood flow could prevent needless stents

Morbidly obese patients face high risk for complications after colectomy

Oral contraceptives may be safe, but information gaps remain

Schering-Plough announces European submission of fertility medicine Corifollitropin Alfa

FDA to review prasugrel for acute coronary syndromes

Seniors warned about mixing OTC and prescription drugs

Stem cells and leukemia battle for marrow microenvironment

New method offers direct access to the brain through the nose to treat stroke

Surgeons perform first simultaneous double-lung, kidney transplant in Illinois, Wisconsin

Hospitals using quality improvement program increase compliance to stroke treatment guidelines

Carbon monoxide used to protect mouse nerve cells from damage

Portola Pharmaceuticals starts phase 2 trial of P2Y12 ADP receptor antagonist in non-urgent percutaneous coronary intervention

Drug combo improves or stabilizes disease for relapsed multiple myeloma patients

Protein could prevent blocked arteries

Recombinant human antithrombin drug decreases risk to pregnancy and surgery patients with hereditary antithrombin deficiency

New approaches to prevent blood clots

Daiichi Sankyo starts trial of investigational factor Xa inhibitor for atrial fibrillation

ACE inhibitor calcium channel blocker combo drug shown to reduces heart attacks

Discovery of new enzyme in cancer growth

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