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FDA-approved breast cancer drug shows promise for appendix cancer

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

16 Oct 2024

Innovative nanoparticle therapy offers hope in fighting prostate cancer

Prostate cancer is the second leading cause of cancer death among American men.

16 Oct 2024

Immunotherapy sets new standard for Hodgkin lymphoma care

A treatment that rallies the immune system to destroy cancer raised the survival rate for advanced Hodgkin lymphoma patients to a remarkable 92 percent, suggesting a new standard therapy for the disease.

16 Oct 2024

Adenine base editors show potential to correct X-CGD-causing mutations

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder characterized by high susceptibility to infections.

16 Oct 2024

Shift Bioscience raises $16 M to advance cell simulation AI platform

Shift Bioscience is a biotech company using generative AI models to understand how activation of different genes can reverse the aging process. This research is a fundamental step forward in designing more effective drugs to treat age-related diseases.

From Shift Bioscience 16 Oct 2024

Short course chemotherapy boosts survival rates in cervical cancer patients

Cervical cancer patients were significantly more likely to be alive and cancer-free after five years when given a short course of chemotherapy prior to chemoradiation, finds a clinical trial led by researchers from UCL and UCLH.

15 Oct 2024

Efforts to increase diversity in cancer clinical trials fall short

In the U.S., millions of people experience cancer every year but don't have an equal opportunity to access experimental treatments in clinical trials, or to receive treatments that were shown to be effective in patients like them.

15 Oct 2024

Distinct immune profiles linked to adverse reactions from immunotherapy

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

15 Oct 2024

Emory University researchers shift focus to neuroinflammation in Alzheimer's treatment

For decades, Alzheimer's research has focused on examining amyloid plaques in the brain and prescribing antibody therapeutics that remove the plaques to slow cognitive decline in patients.

15 Oct 2024

Multidisciplinary approach improves quality of life in functional movement disorders

The research team of the Neurology Department Movement Disorders Unit at the Virgen del Rocío University Hospital and the Movement Disorders group of the Institute of Biomedicine of Seville - IBiS, in collaboration with researchers from the Mental Health Clinical Management Unit and the Translational Psychiatry group coordinated by Benedicto Crespo Facorro (HUVR-IBiS/CIBERSAM), has published a randomized clinical trial demonstrating for the first time that a multidisciplinary approach integrating specific physiotherapy and cognitive-behavioral therapy is effective in improving the symptoms and physical aspects of the quality of life of patients with functional movement disorders.

12 Oct 2024

New study reveals unique metabolic function of lung-resident NK immune cells

Trinity College Dublin researchers, based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown, but crucial 'natural killer' (NK) immune cell resident in the lungs.

12 Oct 2024

Mount Sinai launches new center for complex chronic illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced the grand opening of the Cohen Center for Recovery From Complex Chronic Illnesses (CoRE), providing clinical care for patients with conditions such as long Lyme disease/Lyme+, long COVID, and other infection-associated complex chronic illnesses such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Ehlers-Danlos syndrome (EDS).

10 Oct 2024

Bed availability influences critical care admissions after surgery

Bed availability is a "significant" factor in determining whether or not a patient is admitted to a critical care bed after surgery, questioning whether some are getting the care they need, a new study from researchers at UCL and UCLH has found for the first time.

10 Oct 2024

Skin pigmentation may affect drug efficacy and safety

Skin pigmentation may act as a "sponge" for some medications, potentially influencing the speed with which active drugs reach their intended targets, a pair of scientists report in a perspective article published in the journal Human Genomics.

10 Oct 2024

Dual immunotherapy plus chemotherapy shows promise for specific lung cancer patients

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

9 Oct 2024

Incorrect arm positioning inflates blood pressure readings, risking misdiagnosis

Incorrect arm positioning during blood pressure measurement can overestimate readings, potentially leading to misdiagnosis and overtreatment of hypertension. Proper arm support is essential for accuracy.

8 Oct 2024

Concerns rise over increased industry sponsorship in cancer clinical trials

A growing reliance on industry-sponsored cancer clinical trials in the United States is a reason for concern, say researchers from the UNC Lineberger Comprehensive Cancer Center.

8 Oct 2024

Heat stress impacts development of babies during critical early years

Exposure to high levels of heat may both impact the growth of fetuses during pregnancy and infants up to the age of two, a new analysis suggests.

8 Oct 2024

Electro-acupuncture shows promise in obesity management

A team of scientists led by Nanyang Technological University Singapore (NTU Singapore) and Hong Kong University (HKU) has found evidence that electro-acupuncture - a form of traditional Chinese medicine (TCM) treatment - could be used to manage obesity.

8 Oct 2024

Doxycycline increases antimicrobial resistance in the gut without disrupting microbiome diversity

Doxycycline post-exposure prophylaxis increases tetracycline resistance genes in the gut, without significantly affecting microbiome diversity in men who have sex with men and transgender women.

7 Oct 2024