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X-ray study sheds new light on promising drug target

Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins adorning cell surfaces, which are the targets of the majority of pharmaceutical drugs.

5 Apr 2017

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

In an article published recently in Plos One, researchers from INRS-Institut Armand-Frappier Research Centre reported a strategy that could lead to the discovery of new cationic antimicrobial peptides (CAMPs) with greatly enhanced antimicrobial properties.

5 Apr 2017

Research finding could set stage for potential development of new antimicrobial drugs

Research teams from the National Institutes of Health and abroad have identified the first inhibitor of an enzyme long thought to be a potential drug target for fighting disease-causing parasites and bacteria.

3 Apr 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV.

28 Mar 2017

Neurology researchers on the hunt for biomarker signal for early detection of Alzheimer's disease

Around 100,000 Austrians suffer from Alzheimer's disease and 16,000 from Parkinson's. Experts estimate that, in view of the ageing population, these numbers are set to triple over the next 30 years.

27 Mar 2017

Researchers develop nanoparticle to deliver potential new drug to breast cancer cells

The research, a collaborative project between Queen's University Belfast and Ulster University, began at the Queen's Centre for Cancer Research and Cell Biology in 2014, and was led by Professor Mohamed El-Tanani.

24 Mar 2017

Postnova PN3621 MALS sets new standard for sensitive and precise multi-angle light scattering detection

The PN3621 MALS from Postnova Analytics sets a new standard for sensitive, precise and flexible Multi-Angle Light Scattering detection for Size Exclusion Chromatography (SEC) and Field Flow Fractionation (FFF) systems.

From Pittcon 24 Mar 2017

Research suggests novel strategy to target genetic anomaly in prostate cancers

New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.

24 Mar 2017

Analysis of antibodies could be new tool for predicting prognosis and choosing therapy for RA patients

In rheumatoid arthritis, antibodies are formed that affect the inflammation in the joints. In an article published today in the journal Annals of the Rheumatic Diseases, researchers at Uppsala University show that antibodies against the cartilage protein collagen II are associated with a good prognosis.

23 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

MPFI researchers develop new tool to study CaMKII kinetics in learning and memory

As we learn, the structure of individual neurons in our brains change to strengthen important connections and weaken less important ones, a process known as structural plasticity.

16 Mar 2017

Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Instrument from Postnova represents broadest range of angles available in a commercial light scattering detector

Postnova Analytics PN3621 MALS detector sets a new standard for sensitive, precise and flexible Multi-Angle Light Scattering detection for Size Exclusion Chromatography (SEC) and Field Flow Fractionation (FFF) systems.

From Postnova Analytics 16 Mar 2017

Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

It has been estimated that the number of people with diabetes worldwide reached 422 million in 2014, boosting prevalence to 8.5% among adults over 18 years of age. This figure is expected to rise to 642 million people by 2040.

16 Mar 2017

Exact replication studies may accelerate development of better cancer treatments

In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010-2012.

15 Mar 2017

New class of membrane-busting compounds can combat MRSA skin infections in mice

Public health officials are increasingly concerned over methicillin-resistant Staphylococcus aureus (MRSA). The bacteria have developed resistance to a number of treatments, even antibiotics of last resort in some cases.

15 Mar 2017

Research shows pNaKtide can attenuate development of NAFLD and atherosclerosis

Building on their recent research focusing on a peptide, pNaKtide, designed to block the oxidant amplifying function of the cellular sodium-potassium pump, researchers at Marshall University Joan C. Edwards School of Medicine have successfully demonstrated that pNaKtide, can attenuate the development of experimental nonalcoholic fatty liver disease (NAFLD) and atherosclerosis.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Peptides News and Research

X-ray study sheds new light on promising drug target

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

Research finding could set stage for potential development of new antimicrobial drugs

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Neurology researchers on the hunt for biomarker signal for early detection of Alzheimer's disease

Researchers develop nanoparticle to deliver potential new drug to breast cancer cells

Postnova PN3621 MALS sets new standard for sensitive and precise multi-angle light scattering detection

Research suggests novel strategy to target genetic anomaly in prostate cancers

Analysis of antibodies could be new tool for predicting prognosis and choosing therapy for RA patients

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

MPFI researchers develop new tool to study CaMKII kinetics in learning and memory

Study shows how immune cells drive heart damage in mice

Instrument from Postnova represents broadest range of angles available in a commercial light scattering detector

Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

Exact replication studies may accelerate development of better cancer treatments

New class of membrane-busting compounds can combat MRSA skin infections in mice

Research shows pNaKtide can attenuate development of NAFLD and atherosclerosis

Researchers suggest potential new way to restore healthy intestinal function in older people

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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