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Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Instrument from Postnova represents broadest range of angles available in a commercial light scattering detector

Postnova Analytics PN3621 MALS detector sets a new standard for sensitive, precise and flexible Multi-Angle Light Scattering detection for Size Exclusion Chromatography (SEC) and Field Flow Fractionation (FFF) systems.

From Postnova Analytics 16 Mar 2017

Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

It has been estimated that the number of people with diabetes worldwide reached 422 million in 2014, boosting prevalence to 8.5% among adults over 18 years of age. This figure is expected to rise to 642 million people by 2040.

16 Mar 2017

Exact replication studies may accelerate development of better cancer treatments

In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010-2012.

15 Mar 2017

New class of membrane-busting compounds can combat MRSA skin infections in mice

Public health officials are increasingly concerned over methicillin-resistant Staphylococcus aureus (MRSA). The bacteria have developed resistance to a number of treatments, even antibiotics of last resort in some cases.

15 Mar 2017

Research shows pNaKtide can attenuate development of NAFLD and atherosclerosis

Building on their recent research focusing on a peptide, pNaKtide, designed to block the oxidant amplifying function of the cellular sodium-potassium pump, researchers at Marshall University Joan C. Edwards School of Medicine have successfully demonstrated that pNaKtide, can attenuate the development of experimental nonalcoholic fatty liver disease (NAFLD) and atherosclerosis.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Although Zika and dengue are considered different virus "species," they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology.

13 Mar 2017

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund - the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed to be at the root of Alzheimer's disease.

13 Mar 2017

Study shows how socially contagious itching is hardwired in the brain

Some behaviors — yawning and scratching, for example — are socially contagious, meaning if one person does it, others are likely to follow suit. Now, researchers at Washington University School of Medicine in St. Louis have found that socially contagious itching is hardwired in the brain.

10 Mar 2017

Researchers develop optimized sensors to study biochemical underpinnings of learning and memory

Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity.

9 Mar 2017

Timing of carbohydrate intake plays role in blood glucose regulation for men with prediabetes

According to a nutrition study led by the German Institute of Human Nutrition, a partner of the German Center for Diabetes Research, the so-called internal clock also influences how people with impaired glucose metabolism react to carbohydrate-rich food.

9 Mar 2017

New computer models could help researchers to better predict side-effects of drugs

New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome

8 Mar 2017

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Using red blood cells modified to carry disease-specific antigens, scientists in the laboratories of Hidde Ploegh and Harvey Lodish have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.

7 Mar 2017

Mayo Clinic researchers identify new genetic risk factor for late-onset Alzheimer's in African-Americans

A Mayo Clinic research team has found a new gene mutation that may be a risk factor for late-onset Alzheimer's disease in African-Americans.

28 Feb 2017

Study suggests new strategy for treating Alzheimer's disease

Alzheimer's disease (AD) is one of the most common form of dementia. In search for new drugs for AD, the research team, led by Professor Mi Hee Lim of Natural Science at UNIST has developed a metal-based substance that works like a pair of genetic scissors to cut out amyloid-β (Aβ), the hallmark protein of AD.

28 Feb 2017

MIT researchers develop new machine to rapidly produce customized peptides

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.

27 Feb 2017

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Healthy human skin is alive with bacteria. In fact, there are more microorganisms living in and on the human body than there are human cells. Most can live on the human skin without harming the host, but in some people bacteria can negatively alter their health, maybe even become life-threatening.

23 Feb 2017

Scientists propose potential new treatment for Gaucher disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.

23 Feb 2017

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

In a land where survival is precarious, Komodo dragons thrive despite being exposed to scads of bacteria that would kill less hardy creatures.

22 Feb 2017

Peptides News and Research

Study shows how immune cells drive heart damage in mice

Instrument from Postnova represents broadest range of angles available in a commercial light scattering detector

Study provides new insights into biological mechanisms underpinning type 2 diabetes pathology

Exact replication studies may accelerate development of better cancer treatments

New class of membrane-busting compounds can combat MRSA skin infections in mice

Research shows pNaKtide can attenuate development of NAFLD and atherosclerosis

Researchers suggest potential new way to restore healthy intestinal function in older people

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Study shows how socially contagious itching is hardwired in the brain

Researchers develop optimized sensors to study biochemical underpinnings of learning and memory

Timing of carbohydrate intake plays role in blood glucose regulation for men with prediabetes

New computer models could help researchers to better predict side-effects of drugs

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Mayo Clinic researchers identify new genetic risk factor for late-onset Alzheimer's in African-Americans

Study suggests new strategy for treating Alzheimer's disease

MIT researchers develop new machine to rapidly produce customized peptides

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Scientists propose potential new treatment for Gaucher disease

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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