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Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

Researchers reporting on findings from the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial in the UK are recommending that any therapeutic use of REGEN-COV may be best restricted to individuals without detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Jun 2021

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Researchers in the United States have demonstrated the effectiveness of early treatment with REGEN-COV™ at preventing symptomatic disease among people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jun 2021

Novavax COVID vaccine co-administered with flu vaccine appears safe and effective

Researchers from the UK recently reported the results of a sub-study that evaluates the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine when co-administered with an approved seasonal influenza vaccine.

16 Jun 2021

Studies shed new light on disease processes in tuberculosis

Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery.

16 Jun 2021

SARS-CoV-2 oral vaccine booster shows promise in animal tests

In a recent study published on the pre-print bioRxiv* server, a group of Israeli researchers discusses their progress towards developing an oral multi-antigen SARS-CoV-2 vaccine.

15 Jun 2021

UCLA clinical trial shows efficacy of varenicline on heavy-drinking smokers

A recent UCLA clinical trial has shown encouraging results in helping daily smokers who are also heavy drinkers quit smoking and cut down their alcohol intake.

15 Jun 2021

Treatment-resistant depression relieved by laughing gas

Researchers at the Washington University School of Medicine in St. Louis and the University of Chicago have found that a single, one-hour treatment involving the inhalation of a mixture of oxygen and the anesthetic drug nitrous oxide, also known as laughing gas, can improve symptoms of depression in people resistant to treatment.

15 Jun 2021

REGEN-COV antibody cocktail shown to significantly lower SARS-CoV-2 viral load

In human trials, the interim analysis of 275 participants showed REGEN-COV quickly reduced viral loads. Moreover, this reduction was much faster in people who did not have a high viral load when they started treatment.

15 Jun 2021

Cell therapy improves outcomes for heart failure patients, clinical trial shows

A clinical trial conducted at the University of Louisville has shown for the first time that heart failure treatments using cells derived from the patient's own bone marrow and heart resulted in improved quality of life and reduced major adverse cardiac events for patients after one year.

14 Jun 2021

Calcified Tissue International announces top 10 most impactful papers of 2019

Calcified Tissue International and Musculoskeletal Research is among the leading peer-reviewed journals publishing original preclinical, translational, and clinical research as well as expert reviews in the bone and musculoskeletal field.

13 Jun 2021

Are pre-existing Vitamin D deficiencies linked to COVID-19 severity and mortality?

Even as the COVID-19 pandemic continues to spread and new variants of SARS-CoV-2 emerge, much remains to be known about why severity varies so unpredictably between individuals. A new study, released as a preprint on the medRxiv* server, elucidates the relationship between Vitamin D and COVID-19 severity.

10 Jun 2021

Study reports on the immunogenicity of single-shot COVID-19 vaccine against SARS-CoV-2 variants

In the three months since Johnson & Johnson's COVID-19 vaccine received emergency use authorization from the U.S. Food and Drug Administration, more than 10 million Americans have received the vaccine, according to the Centers for Disease Control and Prevention.

9 Jun 2021

Novel COVID-19 vaccine is safe, generates immune response in healthy adults

The COVID-19 pandemic continues to disrupt and end lives around the world, and public health officials worldwide have recognized vaccines as the critical tools required for controlling the COVID-19 death toll and achieving a return to normal life.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

New drug shows promise against lung cancer caused by genetic mutation

The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial.

8 Jun 2021

ADHD medications may lower suicide risk in children with hyperactivity, behavioral disorders

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania.

7 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a rare form of kidney inflammation (glomerulonephritis) in which the glomeruli become increasingly scarred (sclerotic), leading to progressive loss of kidney function.

7 Jun 2021

Minimally-invasive procedure could offer hope to patients with high blood pressure

A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

7 Jun 2021

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Today, the U.S. Food and Drug Administration approved Aduhelm (aducanumab) for the treatment of Alzheimer's, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.

7 Jun 2021

Placebo News and Research

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Novavax COVID vaccine co-administered with flu vaccine appears safe and effective

Studies shed new light on disease processes in tuberculosis

SARS-CoV-2 oral vaccine booster shows promise in animal tests

UCLA clinical trial shows efficacy of varenicline on heavy-drinking smokers

Treatment-resistant depression relieved by laughing gas

REGEN-COV antibody cocktail shown to significantly lower SARS-CoV-2 viral load

Cell therapy improves outcomes for heart failure patients, clinical trial shows

Calcified Tissue International announces top 10 most impactful papers of 2019

Are pre-existing Vitamin D deficiencies linked to COVID-19 severity and mortality?

Study reports on the immunogenicity of single-shot COVID-19 vaccine against SARS-CoV-2 variants

Novel COVID-19 vaccine is safe, generates immune response in healthy adults

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

New drug shows promise against lung cancer caused by genetic mutation

ADHD medications may lower suicide risk in children with hyperactivity, behavioral disorders

Study reports safety, efficacy of targeted treatment for IgA nephropathy

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Minimally-invasive procedure could offer hope to patients with high blood pressure

FDA grants accelerated approval for first-of-its-kind Alzheimer's treatment

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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