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Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Disrupting sleep-wake cycles from a predominantly daytime to a delayed eating lifestyle, -- i.e., skipping breakfast and making lunch the first meal of the day, plus eating late dinner, disrupts the body's natural circadian (24-hour) rhythm, the cycle that tells us when to sleep, wake up, eat, and influences hormones and other functions.

26 Oct 2017

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors - changes in gene expression versus an alteration in the genetic code -- play an important role.

26 Oct 2017

Healthy heart may protect older adults from disability

A healthy heart is important to the well-being of older adults. The American Heart Association (AHA) defines "ideal cardiovascular health" based on four health behaviors (current smoking, body mass index, physical activity, and healthy diet and three health factors (total cholesterol, blood pressure), and fasting blood glucose level).

26 Oct 2017

Survival of early stage lung cancer patients improves with advancement in surgery, radiation

With the advancement of surgical and radiation therapy strategies for stage 1 non-small-cell lung cancer (NSCLC), more patients are being treated, resulting in higher survival rates, according to a study published online today in The Annals of Thoracic Surgery.

26 Oct 2017

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

Scientists, nephrologists and cardiac surgeons from The Feinstein Institute for Medical Research and Northwell Health's Department of Internal Medicine, Cardiology and Cardio-Thoracic Surgery examined the impact of a popular pre-heart transplant therapy on the kidney in a study published today by The Clinical Journal of the American Society of Nephrology.

26 Oct 2017

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

It is well known that being physically active may lower risks of many diseases, such as heart disease and diabetes. In this study, the scientists studied the link between various measures of exercise and eight biomarkers that have previously related to several chronic diseases.

25 Oct 2017

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem - the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center describe how application of mature B lymphocytes - the immune cells best known for producing antibodies - greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice.

25 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

New study hopes to shed light on mechanism behind epileptic and non-epileptic seizures

Seizures are a common result of traumatic brain injury, especially in military veterans. A new study funded by the DOD, Congressionally Directed Medical Research Programs, and conducted in Providence RI and Birmingham AL hopes to shed new light on the mechanism behind seizures associated with post-traumatic epilepsy and psychogenic nonepileptic seizures.

25 Oct 2017

Study shows feasibility of home monitoring to detect heart arrhythmias in developing fetuses

As reported in the Journal of Perinatology, researchers from Children's Hospital Colorado (Children's Colorado) recently confirmed that it is feasible for at-risk pregnant women to use commercially-available Doppler fetal heart rate monitors for home monitoring to detect heart arrhythmias in their developing fetuses.

25 Oct 2017

Developmental abnormality discovered in babies linked to SIDS

International research involving the University of Adelaide has uncovered a developmental abnormality in babies - especially in premature babies and in boys - that for the first time has been directly linked to cases of sudden infant death syndrome (SIDS).

25 Oct 2017

Women have higher mortality risk than men in the first year after heart attack

Heart attacks pose a greater threat to women than to men. A team at the Technical University of Munich has determined that in the first year after a heart attack women are subject to a significantly higher mortality risk than men with similar case histories.

25 Oct 2017

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Skin plays a surprising role in helping regulate blood pressure and heart rate, according to scientists at the University of Cambridge and the Karolinska Institute, Sweden. While this discovery was made in mice, the researchers believe it is likely to be true also in humans.

25 Oct 2017

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

New assessment system shows which patients need to be examined for heart valve infection

A risk assessment system developed by researchers at Lund University in Sweden shows which patients, with a certain type of streptococcal bacteria in the blood, need to be examined for a heart valve infection - a serious condition requiring prolonged medical treatment.

25 Oct 2017

The painful side of positive health care marketing

Lori Wallace sits on a couch with her 11-year-old son and his new pet snake. It burrows under his armpit, as if afraid. Wallace is sure it’s not.

25 Oct 2017

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

A study led by Mayo Clinic researchers has found that proton beam therapy, in combination with chemotherapy, prior to surgery, may be a better option than a combination using traditional radiation therapy techniques with chemotherapy when treating elderly patients with esophageal cancer.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Weight loss following bariatric operation leads to improvements in heart health

In overweight and obese people, fat often gets deposited in the midsection of the body. Large amounts of this belly fat can lead to unhealthy changes in a heart's function and size.

25 Oct 2017

Heart News and Research

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Healthy heart may protect older adults from disability

Survival of early stage lung cancer patients improves with advancement in surgery, radiation

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

Researchers find rare genetic variants that may help explain longevity in some CF patients

New study hopes to shed light on mechanism behind epileptic and non-epileptic seizures

Study shows feasibility of home monitoring to detect heart arrhythmias in developing fetuses

Developmental abnormality discovered in babies linked to SIDS

Women have higher mortality risk than men in the first year after heart attack

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

New assessment system shows which patients need to be examined for heart valve infection

The painful side of positive health care marketing

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

Researchers mine blood-based epigenetic data to gain insights into autism biology

Weight loss following bariatric operation leads to improvements in heart health

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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