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New target identified for treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine (Volume 244, Issue 9, June 2019) (https://journals.sagepub.com/doi/pdf/10.1177/1535370219843827) identifies a new target for the treatment of idiopathic pulmonary fibrosis.

29 Jun 2019

Researchers develop improved vaccine for meningitis and bloodstream infections

Researchers have now developed a new vaccine, a native outer membrane vesicle vaccine, for meningitis and bloodstream infections caused by "meningococcal group B" bacteria.

29 Jun 2019

New study links low social engagement to amyloid levels and cognitive decline

Social relationships are essential to aging well; research has shown an association between lack of social engagement and increased risk of dementia.

29 Jun 2019

Cutting-edge electron microscopy reveals first structures of a lipid-flippase

Using cutting-edge electron microscopy, researchers from Aarhus University have determined the first structures of a lipid-flippase.

29 Jun 2019

Protein linked to malignant melanoma

Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer.

28 Jun 2019

Mini MRI device could help diagnose knee injuries more quickly and accurately

Researchers at Imperial College London have developed a prototype mini MRI scanner that fits around a patient's leg.

28 Jun 2019

Extremely strenuous exercise can overload the heart without increasing cardiac risk

Researchers have found no evidence of elevated cardiac risk in runners who completed a 24-hour ultramarathon (24UM), despite the transient elevation of blood biomarkers that measure cardiac health.

28 Jun 2019

Anti-aging protein hormone Klotho shown to be neuroprotective in ALS model

Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis.

28 Jun 2019

Endogenous retrovirus type W found to be a major contributor to nerve damage in MS

Early disease stages of MS are primarily characterized by immune cell infiltration of the CNS. This causes inflammation that damages the so-called myelin sheaths.

28 Jun 2019

Scientists discover pathway that prevents buildup of Alzheimer's protein

St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. The report appeared online today in the journal Cell.

28 Jun 2019

Sleep quality could be indicator for later Alzheimer’s disease finds study

A new study from the researchers at the University of California, Berkeley has shown that progressively declining quality of sleep among those in their 50s and 60s could be indicative of protein tangles within their brains that could lead to later development of Alzheimer’s disease.

28 Jun 2019

Scientists reveal insights into how a common Alzheimer's risk gene disrupts brain cells

Insights into how a gene that increases the risk of Alzheimer's disease disrupts brain cells have been revealed by scientists.

27 Jun 2019

Sleep decline in one's 50s, 60s increases risk of Alzheimer's disease

People who report a declining quality of sleep as they age from their 50s to their 60s have more protein tangles in their brain, putting them at higher risk of developing Alzheimer's disease later in life, according to a new study by psychologists at the University of California, Berkeley.

27 Jun 2019

FDA approves first drug for treatment of neuromyelitis optica spectrum disorder

The U.S. Food and Drug Administration today approved Soliris (eculizumab) injection for intravenous use for the treatment of neuromyelitis optica spectrum disorder in adult patients who are anti-aquaporin-4 antibody positive.

27 Jun 2019

Disrupting ChIP Assay Technology with New Advancements

The Chromatrap ChIP technology is a bead-free method of performing ChIP. The potential of the technology emerged from our capabilities in manufacturing porous plastic filters for the filtration and separation of biological materials.

From Chromatrap® - Porvair Sciences Ltd 27 Jun 2019

Compelling New Evidence Further Suggests Parkinson’s Disease Begins in the Gut

A new mouse study has revealed more evidence that Parkinson’s disease originates in the gut before traveling to the brain via the body’s neurons.

27 Jun 2019

Scientists reveal mechanism of tumor metastasis and tumor-suppressive role of UDP-glucose

Scientists from Dalian Institute of Chemical Physics and Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences revealed that UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.

27 Jun 2019

Scientists suggest possible cell-based therapy for premature infants with rare lung condition

Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia, which in the most severe cases can lead to lifelong breathing problems and even death.

27 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019