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India trials investigational vaccine candidate designed to prevent HIV/AIDS

Announcing the trial, Union Minister of Health and Family Welfare Dr. Anbumani Ramadoss, said: "Developing a vaccine to prevent AIDS is one of the most difficult scientific challenges of our time. It is also one of the most urgent health needs. Perseverance is the way forward, and India has a long- term commitment."

7 Feb 2005

Study supports giving dehydrated children fluids by mouth, oral rehydration therapy

Oral rehydration therapy, or giving fluids by mouth, is equally effective as giving intravenous fluids to young children dehydrated by common stomach and intestinal inflammations, according to a new study by emergency medicine physicians.

7 Feb 2005

Solbec announces pre-clinical study to confirm findings into the effect of Coramsine combined with CpG in the treatment of murine mesothelioma

Solbec Pharmaceuticals Ltd has announced the commencement of a pre-clinical study to confirm and extend the findings of an earlier investigation into the effect of Coramsine™ combined with CpG in the treatment of murine mesothelioma.

3 Feb 2005

Nearly 10,000 preterm births could have been prevented in 2002

Nearly 10,000 preterm births could have been prevented in 2002 if all pregnant women at high risk for a premature baby and eligible for weekly injections of a derivative of the hormone progesterone had received them, according to a new study published in the February issue of Obstetrics & Gynecology.

31 Jan 2005

Study focuses on best treatment for older women with receptor negative early breast cancer

Older women with hormone receptor negative early breast cancer who may currently be missing out on effective post-operative anticancer drugs will be able to participate in a new clinical trial specifically aimed at this group of women.

27 Jan 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex

Adhesions – bands of scar tissue that bind together two internal body surfaces – develop in 55 percent to more than 90 percent of patients undergoing surgery, depending on the type of operation. They are part of normal healing, but when surfaces fuse together that shouldn't, serious pain and complications can result.

26 Jan 2005

Calcium boost to youths' bones could reduce osteoporosis risk

New research on calcium and bone development suggests that efforts to prevent osteoporosis, generally considered a geriatric disease among women, could actually start before puberty.

26 Jan 2005

Drug reviparin reduces the risk of death after heart attack

The drug reviparin (a low molecular weight heparin anticoagulant), when administered to patients with a heart attack, is effective in reducing the risk of death and the risk of a subsequent heart attack, according to a study in the January 26 issue of JAMA.

26 Jan 2005

Genzyme files Glucocerebrosidase patent infringement

Genzyme announced today that it has filed a lawsuit in the District Court of Tel Aviv alleging that Transkaryotic Therapies Inc. has infringed Genzyme's Israeli patent No. 100,715, which covers certain cell culture processes involved in the manufacture of glucocerebrosidase.

25 Jan 2005

Vioxx could have caused 140000 excess cases of coronary heart disease in the USA since 1999

The arthritis drug Vioxx could have caused an estimated 88 000–140 000 excess cases of serious coronary heart disease in the USA since its launch in 1999, concludes a study published online by The Lancet.

24 Jan 2005

Clinical trial planned for stem cell treatment for stress urinary incontinence

ITL Laboratories, L.L.C. ("ITL") is planning a clinical trial to determine the effectiveness of a stem cell treatment for stress urinary incontinence. A recent clinical trial by Austrian researchers has demonstrated the potential usefulness of expanded muscle stem cell injections in the treatment of urinary incontinence.

24 Jan 2005

Health authorities reviewing scientific data from trials evaluating Alzheimer's treatment, Reminyl

Johnson & Johnson Pharmaceutical Research & Development, LLC (J&JPRD) announced that health authorities are reviewing scientific data from two clinical trials evaluating an investigational use of the company's Alzheimer's treatment, Reminyl (galantamine hydrobromide), in individuals with mild cognitive impairment.

24 Jan 2005

Serono completes enrollment in phase III trial of Serostim

Serono has announced that it has completed enrollment in its second multi-center, phase III trial of Serostim (somatropin [rDNA origin] for injection) in the treatment of HIV-Associated Adipose Redistribution Syndrome (HARS).

24 Jan 2005

Antioxidants do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease

A review of recent studies suggests that antioxidant supplements, including vitamin E and selenium, do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease.

24 Jan 2005

NIH begins Phase 1 clinical trial of HIV vaccine candidate

GenVec announced today that the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has begun the second Phase 1 clinical trial in healthy adult volunteers of an HIV vaccine candidate jointly developed by the Dale and Betty Bumpers Vaccine Research Center (VRC), a part of NIAID, and GenVec.

19 Jan 2005

FDA knocks back anticancer drug Marqibo

Inex Pharmaceuticals announced today that United States Food and Drug Administration (FDA) provided an action letter detailing that the anticancer drug Marqibo (vincristine sulfate liposomes injection) is "not approvable" under the FDA's accelerated approval regulations based on the phase 2 clinical trial data submitted.

19 Jan 2005

Further evidence for the role of cyclooxygenases (COX) in heart-disease risk

In two articles, published in Circulation, researchers from the University of Pennsylvania School of Medicine provide further evidence for the role of cyclooxygenases (COX) in heart-disease risk.

17 Jan 2005

Researchers attack cervical cancer

As more and more promising results of clinical trials on vaccination against human papillomaviruses are published, the more likely it becomes that an HPV vaccine will be the first licensed immunization against a sexually transmitted disease.

17 Jan 2005

Clinical Trial News and Research

India trials investigational vaccine candidate designed to prevent HIV/AIDS

Study supports giving dehydrated children fluids by mouth, oral rehydration therapy

Solbec announces pre-clinical study to confirm findings into the effect of Coramsine combined with CpG in the treatment of murine mesothelioma

Nearly 10,000 preterm births could have been prevented in 2002

Study focuses on best treatment for older women with receptor negative early breast cancer

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex

Calcium boost to youths' bones could reduce osteoporosis risk

Drug reviparin reduces the risk of death after heart attack

Genzyme files Glucocerebrosidase patent infringement

Vioxx could have caused 140000 excess cases of coronary heart disease in the USA since 1999

Clinical trial planned for stem cell treatment for stress urinary incontinence

Health authorities reviewing scientific data from trials evaluating Alzheimer's treatment, Reminyl

Serono completes enrollment in phase III trial of Serostim

Antioxidants do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease

NIH begins Phase 1 clinical trial of HIV vaccine candidate

FDA knocks back anticancer drug Marqibo

Further evidence for the role of cyclooxygenases (COX) in heart-disease risk

Researchers attack cervical cancer

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Why use light scattering to analyze proteins and viral vectors?

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