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BioInvent, ThromboGenics announce results from TB-402 Phase IIb trial on VTE

ThromboGenics NV and co-development partner BioInvent International announce today the results from a Phase IIb trial comparing TB-402, a long acting anticoagulant, against rivaroxaban, an oral anticoagulant.

5 Jun 2012

Preoperative breast cancer pain involves an inflammatory process

Researchers from the University of California San Francisco studied a sample of women scheduled for breast cancer surgery and sought to determine the occurrence rate for preoperative breast pain, describe characteristics of the pain, evaluate the demographic and clinical variation in the women with preoperative pain, and assess the role of in pro-and anti inflammatory cytokine genes.

5 Jun 2012

Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer

Celgene International Sàrl, a subsidiary of Celgene Corporation today announced results from a study of ABRAXANE(paclitaxel protein-bound particles for injectable suspension) (albumin-bound) in combination with gemcitabine in patients with resectable pancreatic cancer.

5 Jun 2012

Ipsen, Active Biotech present OS data from tasquinimod Phase II study on CRPC at ASCO 2012

Active Biotech and Ipsen today presented overall survival (OS) data from the tasquinimod Phase II study in chemotherapy-naïve metastatic castrate resistant prostate cancer (CRPC) at the scientific conference "2012 ASCO Annual Meeting" held in Chicago (USA).

5 Jun 2012

Positive results from BioSpecifics’ XIAFLEX Phase III clinical program on Peyronie's disease

BioSpecifics Technologies Corp., a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX in the U.S. and XIAPEX in Europe and Eurasia, today announced positive top-line results from the IMPRESS (The Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies) Phase III clinical program of XIAFLEX for the treatment of Peyronie's disease, which was conducted by BioSpecifics' partner Auxilium Pharmaceuticals, Inc.

5 Jun 2012

MitrAssist receives ISO certification for design and development of mitral valve prosthesis

MitrAssist Medical Ltd., a developer of minimally invasive products for treating heart disease, announced today that it received ISO 13485:2003 Certification for the design and development of implantable heart valve prostheses.

4 Jun 2012

Positive results from Auxilium’s XIAFLEX phase III studies on Peyronie's disease

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced positive top-line results from its IMPRESS (The Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies) trials, the phase III studies that assessed XIAFLEX (collagenase clostridium histolyticum or CCH), a novel, in-office, first-in-class biologic therapy for the potential treatment of Peyronie's disease (PD).

4 Jun 2012

Variation in microRNAs may explain survival differences in breast cancer

Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with African American and Caucasian patients.

4 Jun 2012

Study reveals why GBM is highly resistant to current chemotherapies

New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies.

2 Jun 2012

Researchers uncover fundamental properties of key molecular signaling system using optical tweezers

By using a laser microbeam technology called optical tweezers, UC Irvine and UCLA researchers have uncovered fundamental properties of a key molecular signaling system involved with development, cancer and cardiovascular disease.

2 Jun 2012

New molecular test panel to enhance reliability of thyroid biopsy testing

Quest Diagnostics, the world's leading provider of diagnostic testing, information and services, today announced a new molecular test panel designed to help physicians determine if a thyroid gland is cancerous and requires surgical removal.

From Quest Diagnostics 2 Jun 2012

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have shown promising early results in patients with advanced non-small cell lung cancer, melanoma, and kidney cancer.

2 Jun 2012

Akron General Medical Center to install Brainsuite iMRI and iCT integrated neurosurgical suites

Brainlab, a manufacturer of software-driven systems for targeted, less-invasive medical treatments, announced today that Akron General Medical Center will install both Brainsuite iMRI and iCT, making it one of only a handful of hospitals in the world to offer both solutions.

2 Jun 2012

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

Investigators at The Cancer Institute of New Jersey (CINJ) have partnered with the National Cancer Institute (NCI) and launched a clinical trial examining the effectiveness of a combined vaccine and hormone treatment for prostate cancer that is resistant to hormone therapy and not visible on imaging tests such as a CT scan and a bone scan.

2 Jun 2012

Majority of patients undergoing CTAP in ED are classified as clinically complex

The overwhelming majority (93.8 percent) of patients undergoing computed tomography (CT) of the abdomen and pelvis (CTAP) in the emergency department (ED) setting are classified as clinically complex, according to a study in the June issue of the Journal of the American College of Radiology. Clinically complex is used to describe patients who are, based on documentation of their ED physician, much sicker than others.

2 Jun 2012

Agendia launches ColoPrint microarray-based 18-gene expression signature for colon cancer

Agendia, an innovative molecular cancer diagnostics company and leader in personalized medicine, today announced the launch of its ColoPrint microarray-based 18-gene expression signature for predicting the risk of distant recurrence for stage II colon cancer patients who have undergone surgery.

2 Jun 2012

HNC patients may be at increased risk for post-treatment side effects

New data from an Internet-based study show that patients with head and neck cancers (HNC) may be at risk for significant late effects after their treatment, but they're unlikely to discuss these and other survivorship care issues with their doctors.

2 Jun 2012

Study identifies several proteins as new therapeutic targets and biomarkers for kidney cancer

Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up validation testing, inhibition of these proteins and several related pathways holds promise as a form of therapy to slow the growth of kidney tumors.

2 Jun 2012

European Multidisciplinary Meeting on Urological Cancers to be held in Barcelona

With the goal to deliver an in-depth review of the latest multi-modal management strategies for urological cancers, the 4th European Multidisciplinary Meeting on Urological Cancers (EMUC) will be held from 16 to 18 November 2012 in Barcelona, Spain.

2 Jun 2012

Skin transplants benefit vitiligo patients

Patients with the skin disease vitiligo may benefit from surgery in which skin cells from unaffected areas of the body are transplanted into damaged areas to restore color, say researchers.

1 Jun 2012

Surgery News and Research

BioInvent, ThromboGenics announce results from TB-402 Phase IIb trial on VTE

Preoperative breast cancer pain involves an inflammatory process

Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer

Ipsen, Active Biotech present OS data from tasquinimod Phase II study on CRPC at ASCO 2012

Positive results from BioSpecifics’ XIAFLEX Phase III clinical program on Peyronie's disease

MitrAssist receives ISO certification for design and development of mitral valve prosthesis

Positive results from Auxilium’s XIAFLEX phase III studies on Peyronie's disease

Variation in microRNAs may explain survival differences in breast cancer

Study reveals why GBM is highly resistant to current chemotherapies

Researchers uncover fundamental properties of key molecular signaling system using optical tweezers

New molecular test panel to enhance reliability of thyroid biopsy testing

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Akron General Medical Center to install Brainsuite iMRI and iCT integrated neurosurgical suites

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

Majority of patients undergoing CTAP in ED are classified as clinically complex

Agendia launches ColoPrint microarray-based 18-gene expression signature for colon cancer

HNC patients may be at increased risk for post-treatment side effects

Study identifies several proteins as new therapeutic targets and biomarkers for kidney cancer

European Multidisciplinary Meeting on Urological Cancers to be held in Barcelona

Skin transplants benefit vitiligo patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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