Omicron News and Research

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Study explores protection against Omicron and Delta infections by COVID-19 vaccination and previous infection

A new study demonstrated that infection- and vaccine-induced protection induced by the primary COVID-19 vaccination was much reduced for the Omicron BA.1 infection compared to the Delta infection.

10 Feb 2022

Rapid generation and evaluation of an mRNA vaccine candidate specific to Omicron

A recent study demonstrated the development of a potential SARS-CoV-2 Omicron variant-specific mRNA vaccine candidate.

10 Feb 2022

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Researchers investigated the efficacy of two multi-kinase inhibitors, olverembatinib and ponatinib, in inhibiting SARS-CoV-2 omicron-mediated cytokine release in human peripheral blood mononuclear cells.

10 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

The effect of Omicron mutations at the fundamental atomic scale level

The present study provided interesting insights into the interactions of AAs at the interface between SARS-CoV-2 spike and human ACE2 receptors.

10 Feb 2022

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

In two recent studies, researchers at Washington University School of Medicine in St. Louis found evidence that the omicron variant of the virus that causes COVID-19 causes less severe disease than previous variants — at least in rodents — but that many antibody-based therapies may not be effective against it.

10 Feb 2022

First computational model simulates many variables affecting COVID-19 transmission

Researchers at the University of Waterloo created the first computational model that simulates many variables affecting the transmission of COVID-19 to slow the spread of variants.

10 Feb 2022

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

A study published on the bioRxiv* preprint server evaluates molnupiravir against a panel of relevant VOCs using three efficacy models: primary human airway epithelium organoids, a ferret model of upper respiratory disease, and a Roborovski dwarf hamster model for severe COVID-19.

9 Feb 2022

Machine learning highly effective at identifying SARS-CoV-2 variants

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9 Feb 2022

The serious risks COVID-19 may pose during pregnancy

Researchers report on the potential for serious maternal illness or death during or following a pregnancy complicated by COVID-19.

9 Feb 2022

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

Researchers describe the impact of changes in the Omicron variant on a uniquely immunodominant spike-encoded CD8+ T-cell epitope.

9 Feb 2022

University of Michigan expert discusses about COVID-19 vaccine for kids under 5

The FDA will consider authorizing two doses of a COVID-19 vaccine for kids under 5 on an emergency basis, with the possibility for a third.

9 Feb 2022

Exploring omicron infection in COVID-19 vaccinated and convalescent South African healthcare workers

In a new study, researchers evaluated healthcare workers in South Africa, presenting with SARS-CoV-2 symptoms, for infection by the Omicron variant.

9 Feb 2022

Study compares the neutralizing potential of antibodies against two Omicron variants

A new study investigates if the two SARS-CoV-2 Omicron variants BA.1 and BA.2 are comparable with respect to their ability to evade the host immunity induced by vaccination or prior infection.

9 Feb 2022

mRNA COVID-19 vaccines shown to provide high level of protection against severe SARS-CoV-2 omicron infection

Scientists have recently studied the duration of protection provided by mRNA-based COVID-19 vaccines against symptomatic omicron infection, and associated severity and mortality.

9 Feb 2022

Polio, chickenpox, measles, now covid. It’s time to consult history on school vaccine mandates

The rapid spread of omicron across the nation — and the finding that vaccines continue to provide strong protection against severe disease — brings covid-19 one step closer, perhaps, to truly earning its place on the list of diseases that have been tamed by vaccines.

9 Feb 2022

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

A study by researchers from the United Kingdom finds no difference in the protection offered by mRNA vaccine boosters against the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) when comparing those that have received BioNTech/Pfizer vaccine as a primary course to those that have received Oxford/AstraZeneca.

8 Feb 2022

Omicron News and Research

Study explores protection against Omicron and Delta infections by COVID-19 vaccination and previous infection

Rapid generation and evaluation of an mRNA vaccine candidate specific to Omicron

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The effect of Omicron mutations at the fundamental atomic scale level

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

First computational model simulates many variables affecting COVID-19 transmission

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

Machine learning highly effective at identifying SARS-CoV-2 variants

The serious risks COVID-19 may pose during pregnancy

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

University of Michigan expert discusses about COVID-19 vaccine for kids under 5

Exploring omicron infection in COVID-19 vaccinated and convalescent South African healthcare workers

Study compares the neutralizing potential of antibodies against two Omicron variants

mRNA COVID-19 vaccines shown to provide high level of protection against severe SARS-CoV-2 omicron infection

Polio, chickenpox, measles, now covid. It’s time to consult history on school vaccine mandates

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

Swedish study shows fully vaccinated are protected against severe COVID-19

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

Exploring the high incidence of croup in children during the SARS-CoV-2 Omicron wave

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