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Biopsies of donated kidneys may not be useful for assessing organ quality prior to transplantation

A new study indicates that biopsies of donated kidneys are likely not useful for assessing organ quality prior to transplantation unless standards are set for how they should be performed and interpreted. The findings appear in an upcoming issue of CJASN.

24 Jan 2020

Structural features of donated kidneys may influence their longevity in recipients

New research indicates that subtle structural features of donated kidneys from living donors may predict the risk of kidney transplant failure in recipients.

24 Jan 2020

Scientists use human stem cells to make pain-killing neurons

Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

23 Jan 2020

Study casts doubt on the reliability of donated kidney assessment for transplant

A study led by researchers at Columbia University Irving Medical Center have made an important discovery about the way donated kidneys are assessed before transplantation, that could call into question current decision-making processes about whether an organ can be used or not.

23 Jan 2020

Study demonstrates striking improvements in bone marrow transplants since mid-2000s

A bone marrow transplant can be a lifesaving treatment, but it can come with life-threatening risks.

20 Jan 2020

Liver mesenchymal stromal cells could be a better option for many therapeutic applications

Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value.

20 Jan 2020

Harmful genetic mutations in healthy donors' stem cells may create problems in AML patients

A stem cell transplant - also called a bone marrow transplant - is a common treatment for blood cancers, such as acute myeloid leukemia.

16 Jan 2020

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina, has taken a vital step toward commercializing an innovative diagnostic technique that could better predict kidney transplant success in patients with focal segmental glomerulosclerosis (FSGS), a kidney disease that often leads to end-stage renal failure.

14 Jan 2020

Biomaterial-based vaccine has potential to completely eliminate AML cells

Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients.

14 Jan 2020

Researchers uncover genetic anomaly linked with poor response to common asthma treatment

A new Cleveland Clinic study has uncovered a genetic anomaly associated with poor response to a common asthma treatment.

13 Jan 2020

Human liver manages to stay alive outside the body for a week

Scientists from University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have managed to keep human livers alive for a week outside the body using machines. If successful on large scale trials, this could be a breakthrough for organ transplants and donor organs could be stored outside the body for longer, speculate researchers.

13 Jan 2020

Researchers provide first robust cell culture model for hepatitis E virus

Even though hepatitis E causes over three million infections and about 70,000 deaths each year, the virus has been little studied as yet.

13 Jan 2020

MGH surgeons perform first-of-its-kind heart transplant in New England

A team of surgeons and specialists at Massachusetts General Hospital is announcing an achievement in transplant surgery today, having recently performed the largest number of adult heart transplants in the country using what are known as Donation after Circulatory Death donor hearts.

11 Jan 2020

FDA clears patient-specific airway stents developed by Cleveland Clinic physician

The U.S. Food and Drug Administration (FDA) has cleared patient-specific airway stents developed by Cleveland Clinic physician Tom Gildea, M.D.

9 Jan 2020

Scientists identify 'modifier gene' that determines severity of inherited kidney disease

Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments.

9 Jan 2020

House Energy and Commerce Committee scheduled to hold hearing on immunosuppressive drug coverage

The House Energy and Commerce Committee is scheduled to hold a hearing on Wednesday, January 8, on the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act of 2019, advancing a long-standing legislative priority of the American Society of Nephrology.

9 Jan 2020

Study: Hundreds of discarded kidneys can be transplanted safely and effectively

A new Johns Hopkins Medicine-led study provides the strongest evidence to date that hundreds of deceased donor kidneys, discarded each year after being deemed not suitable under current medical criteria, can be transplanted safely and effectively.

8 Jan 2020

Heart transplants from hepatitis C–positive donors could help overcome organ shortage

One-year survival was similar for adults with severe heart failure who received a heart transplant from a donor with hepatitis C compared to those who received hearts from donors who did not have hepatitis C, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.

8 Jan 2020

Clinical trial tests experimental stem cell treatment against best available drugs for MS

A clinical trial has begun testing an experimental stem cell treatment against the best available biologic therapies for severe forms of relapsing multiple sclerosis.

7 Jan 2020

Can FDA-approved flu shots be repurposed as treatments for cancer?

Changing the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and clinical studies including the most recent use of checkpoint inhibitory antibodies.

7 Jan 2020

Transplant News and Research

Biopsies of donated kidneys may not be useful for assessing organ quality prior to transplantation

Structural features of donated kidneys may influence their longevity in recipients

Scientists use human stem cells to make pain-killing neurons

Study casts doubt on the reliability of donated kidney assessment for transplant

Study demonstrates striking improvements in bone marrow transplants since mid-2000s

Liver mesenchymal stromal cells could be a better option for many therapeutic applications

Harmful genetic mutations in healthy donors' stem cells may create problems in AML patients

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

Biomaterial-based vaccine has potential to completely eliminate AML cells

Researchers uncover genetic anomaly linked with poor response to common asthma treatment

Human liver manages to stay alive outside the body for a week

Researchers provide first robust cell culture model for hepatitis E virus

MGH surgeons perform first-of-its-kind heart transplant in New England

FDA clears patient-specific airway stents developed by Cleveland Clinic physician

Scientists identify 'modifier gene' that determines severity of inherited kidney disease

House Energy and Commerce Committee scheduled to hold hearing on immunosuppressive drug coverage

Study: Hundreds of discarded kidneys can be transplanted safely and effectively

Heart transplants from hepatitis C–positive donors could help overcome organ shortage

Clinical trial tests experimental stem cell treatment against best available drugs for MS

Can FDA-approved flu shots be repurposed as treatments for cancer?

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